Drugs / Cortisone acetate
Cortisone acetate
also known as
cortisone · Cortate · Cortelan · Cortisona · Cortisone 21-acetate · Cortisone aceticum · Cortistab · Cortisyl · +2 more
Other / unclassified targets NR3C1 via activation
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | CORTONE | — | 1950-06-13 | fda.gov ↗ |
Trials 3
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| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 31 trial | ||||||
| Phase 3 | NCT06260462 | Jan 2012 → Sep 2022 | adrenocortical insufficiency | University of Palermo | Completed | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT03760835 | Aug 2016 → Dec 2026 expected | classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency | Federico II University | Recruiting | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT05086926 | Oct → Dec 2021 | pes anserinus tendinitis or bursitis, tendinitis | Aalborg University | Unknown | No outcome recorded |
| Comparator or background therapy10 trials | ||||||
| Phase 2 | NCT01771328 Comparator | Feb 2013 → Jan 2017 | congenital adrenal hyperplasia | Haukeland University Hospital | Unknown | No outcome recorded |
| Phase 2 | NCT01154361 Comparator | — | angioedema | Technical University of Munich | Completed | Met primary |
| Phase 2/3 | NCT03580148 Comparator | Oct 2015 → Jul 2020 | osteoarthritis | Women's College Hospital | Completed | No outcome recorded |
| Phase 3 | NCT01843530 Background | Nov 2013 → Oct 2018 | renin-angiotensin-aldosterone system-blocker-induced angioedema | Technical University of Munich | Completed | No outcome recorded |
| Phase 4 | NCT06178146 Background | Sep 2023 → Nov 2024 | — | Jun Wang | Unknown | No outcome recorded |
| Phase 4 | NCT02277587 Comparator | Mar 2014 → Jun 2016 | primary adrenal insufficiency, secondary adrenal insufficiency | University of Roma La Sapienza | Completed | No outcome recorded |
| Phase 4 | NCT02639039 Comparator | Feb 2013 → Jul 2015 | — | Scott and White Hospital & Clinic | Completed | No outcome recorded |
| — | NCT02918136 Comparator | Dec 2016 → Jul 2018 | rotator cuff syndrome | InGeneron, Inc. | Completed | No outcome recorded |
| — | NCT02196155 Comparator | Jul 2016 → Dec 2026 expected | plantar fasciitis | Insel Gruppe AG, University Hospital Bern | Recruiting | No outcome recorded |
| — | NCT00951236 Comparator | May 2009 → ? | tenosynovitis, trigger thumb | Rothman Institute Orthopaedics | Unknown | No outcome recorded |
Evidence & citations 16 cited values
Every value below carries the sentence it was read from. 15 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | cortisone acetate | “Cortisone Acetate (dose 25 to 37.5 mg) will be continued as before entering the study.” NCT02277587 ↗4“conventional GCs (cortisone acetate or hydrocortisone)” PMID 39171906 ↗ Aug 2024 |
| Known as | Cortate | ChEMBL registry synonym — accepted as the source's own label CHEMBL1650 ↗ |
| Known as | Cortelan | ChEMBL registry synonym — accepted as the source's own label CHEMBL1650 ↗ |
| Known as | Cortisona | ChEMBL registry synonym — accepted as the source's own label CHEMBL1650 ↗ |
| Known as | cortisone | “The project manager will give the participants one injection with cortisone and lidocaine in the lateral hip at baseline.” NCT05086926 ↗ |
| Known as | Cortisone 21-acetate | ChEMBL registry synonym — accepted as the source's own label CHEMBL1650 ↗ |
| Known as | Cortisone aceticum | ChEMBL registry synonym — accepted as the source's own label CHEMBL1650 ↗ |
| Known as | Cortistab | ChEMBL registry synonym — accepted as the source's own label CHEMBL1650 ↗ |
| Known as | Cortisyl | ChEMBL registry synonym — accepted as the source's own label CHEMBL1650 ↗ |
| Known as | Cortone | ChEMBL registry synonym — accepted as the source's own label CHEMBL1650 ↗ |
| Known as | NSC-49420 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1650 ↗ |
| Action | Activate | “Glucocorticoid receptor agonist” CHEMBL1650 ↗ |
| Action | Restore | “glucocorticoid and mineralocorticoid replacement” NCT01771328 ↗ |
| Modality | Other / unclassified | “Cortisone (corticosteroid) injection into the lateral hip” PMID 28257614 ↗ Mar 2017 |
| Route | Intravenous | “Cortisone + Clemastin (intravenous) and plazebo (subcutaneous)” NCT01154361 ↗ |
| Target | NR3C1 | “Glucocorticoid receptor agonist” CHEMBL1650 ↗ |