drugset / Trial / NCT03760835
Congenital Adrenal Hyperplasia Once Daily Hydrocortisone Treatment
RandomizedParallel-groupOpen-labelTreatment
Summary
This is a controlled, open study designed to compare the effects of dual-release hydrocortisone preparations versus conventional glucocorticoid therapy on clinical, anthropometric parameters, metabolic syndrome, hormonal profile, bone status, quality of life, reproductive, sexual and psychological functions and treatment compliance in patients affected by congenital adrenal hyperplasia due to 21 OH deficiency.
Timeline
- Start
- 2016-08-11
- Primary completion
- 2026-12-31
- Completion
- 2027-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cortisone acetate | Other / unclassified | — | — |
| Subject | Dexamethasone | Small molecule | — | — |
| Subject | Hydrocortisone | Other / unclassified | — | — |
| Subject | Hydrocortisone | Other / unclassified | — | Oral |
| Subject | Prednisolone | Other / unclassified | — | — |
| Subject | Prednisone | Other / unclassified | — | — |