Drugs / TPX4589

Trials 11 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT05001516 Dec 2021 → Jan 2024 neoplasm Turning Point Therapeutics, Inc. Completed No outcome recorded
Phase 1/23 trials
Phase 1/2 NCT05994001 Aug 2023 → May 2026 overdue biliary tract cancer Shanghai Zhongshan Hospital Active not recruiting No outcome recorded
Phase 1/2 NCT05188664 May 2022 → Nov 2023 neoplasm LaNova Medicines Limited Completed No outcome recorded
Phase 1/2 NCT05161390 Nov 2021 → Jan 2025 neoplasm LaNova Medicines Zhejiang Co., Ltd. Completed No outcome recorded
Phase 25 trials
Phase 2 NCT07569068 Apr 2026 → Apr 2028 expected gastroesophageal adenocarcinoma Ruijin Hospital Recruiting No outcome recorded
Phase 2 NCT07108504 Aug 2025 → Aug 2026 overdue chemotherapy-induced toxicity, malignant pancreatic neoplasm Shanghai Zhongshan Hospital Not yet recruiting No outcome recorded
Phase 2 NCT06519591 Feb 2025 → May 2026 overdue gastric cancer, peritoneal carcinomatosis Ruijin Hospital Recruiting No outcome recorded
Phase 2 NCT06587425 Jul 2024 → Jul 2025 overdue adenocarcinoma Shanghai Zhongshan Hospital Recruiting No outcome recorded
Phase 2 NCT05934331 Jul 2023 → Jul 2026 overdue digestive system cancer LaNova Medicines Zhejiang Co., Ltd. Recruiting No outcome recorded
Phase 32 trials
Phase 3 NCT07385703 Apr 2026 → Oct 2028 expected adenocarcinoma Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd. Recruiting No outcome recorded
Phase 3 NCT06351020 Jun 2024 → Nov 2026 expected gastric adenocarcinoma LaNova Medicines Zhejiang Co., Ltd. Active not recruiting No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT07556640 Background Apr 2026 → Apr 2028 expected gastric cancer, gastroesophageal adenocarcinoma, peritoneal carcinomatosis Ruijin Hospital Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 12 sources stand behind the page.

FieldValueCited text
Known as TPX4589 “LM-302 (TPX4589)” NCT05001516
Known as LM-302 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05188664
11

NCT06351020

NCT05001516

NCT05161390

NCT07108504

NCT07556640

NCT07569068

NCT06519591

NCT06587425

NCT05994001

NCT05934331

NCT07385703

Modality Other / unclassified “LM-302 :ClAUDIN 18.2-ADC” NCT05994001
Route Intravenous “dose of LM-302 intravenous infusion on day 1” NCT05001516
Target CLDN18 “LM-302, an ADC specifically targeting CLDN18.2 and comprising a monoclonal antibody conjugated to MMAE” NCT06587425