drugset / Trial / NCT06351020

LM-302 for the Treatment of Subjects With Claudin18.2-Positive Gastric and Gastroesophageal Junction Adenocarcinoma.

NCT06351020

Phase 3 Active not recruiting 387 enrolled LaNova Medicines Zhejiang Co., Ltd.
RandomizedParallel-groupOpen-labelTreatment

Summary

This study will assess the efficacy and safety of LM-302 Versus Treatment of Physician's Choice (TPC) in Subjects With locally advanced or metastatic, Claudin (CLDN) 18.2-positive, Gastric or Gastroesophageal Junction Adenocarcinoma who have progressed on or after 2 lines of systemic therapy

Timeline

Start
2024-06-24
Primary completion
2026-11-10
Completion
2026-12-15

Drugs

EvaluationDrugModalityDoseRoute
Comparator Irinotecan Small molecule Intravenous
Comparator Rivoceranib Small molecule Oral
Subject TPX4589 Other / unclassified Intravenous