drugset / Trial / NCT06351020
LM-302 for the Treatment of Subjects With Claudin18.2-Positive Gastric and Gastroesophageal Junction Adenocarcinoma.
RandomizedParallel-groupOpen-labelTreatment
Summary
This study will assess the efficacy and safety of LM-302 Versus Treatment of Physician's Choice (TPC) in Subjects With locally advanced or metastatic, Claudin (CLDN) 18.2-positive, Gastric or Gastroesophageal Junction Adenocarcinoma who have progressed on or after 2 lines of systemic therapy
Timeline
- Start
- 2024-06-24
- Primary completion
- 2026-11-10
- Completion
- 2026-12-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Irinotecan | Small molecule | — | Intravenous |
| Comparator | Rivoceranib | Small molecule | — | Oral |
| Subject | TPX4589 | Other / unclassified | — | Intravenous |