Drugs / MK-8266
last change Mar 2011 re-read 3 minutes ago

MK-8266

Developed for
hypertensive disorder
Investigated by
Merck Sharp & Dohme LLC

Trials 4

201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT01263314 Nov 2010 → Feb 2011 hypertensive disorder Merck Sharp & Dohme LLC Completed Mixed
Phase 1 NCT01244035 Aug → Dec 2010 hypertensive disorder Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 1 NCT01096160 Mar → Nov 2010 hypertensive disorder Merck Sharp & Dohme LLC Completed Mixed
Phase 1 NCT01025791 Nov 2009 → May 2010 hypertensive disorder Merck Sharp & Dohme LLC Completed Met primary

Evidence & citations 2 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as MK8266 “MK-8266 1.3 mg orally twice daily (BID, 1 mg in the morning and 0.3 mg 8 hours later) plus placebo to match Treatment B on Days 1 through 3. On Day 4, single dose of 1 mg MK-8266.” NCT01244035 ↗
4

“A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MK8266 in Hypertensive Men (MK-8266-002)” NCT01096160 ↗

NCT01025791 ↗

NCT01263314 ↗

NCT01096160 ↗

Route Oral “Single oral doses of 0.1 to 1.2 mg of MK-8266 in 0.1 capsule form.” NCT01025791 ↗