drugset / Trial / NCT01244035

Safety, Pharmacodynamics, and Pharmacokinetics of Different Dosing Regimens of MK-8266 in Participants With Hypertension (MK-8266-008)

NCT01244035 ↗

Phase 1 Completed 31 enrolled Merck Sharp & Dohme LLC
RandomizedCrossoverDouble-blindTreatment

Summary

This was designed as a two part study comprising sequential double-dummy, placebo controlled 3-period randomized crossover studies. The study will evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of different doses and dose regimens of MK-8266. Only Part I of the study was completed.

Timeline

Start
2010-08-19
Primary completion
2010-12-23
Completion
2010-12-23

Drugs

EvaluationDrugModalityDoseRoute
Subject MK-8266 Unknown 0.9 mg Oral
Subject MK-8266 Unknown 1.3 mg Oral
Subject MK-8266 Unknown 1.4 mg Oral

Indications