Drugs / Trimethaphan
Trimethaphan
also known as
Camsilate de trimetaphan · Cansilato de trimetafan · Trimetaphan · Trimethaphan cation · Trimethaphan ion
Trials 9 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 18 trials | ||||||
| Phase 1 | NCT03028571 | Apr 2017 → Dec 2022 | — | Vanderbilt University Medical Center | Withdrawn | No outcome recorded |
| Phase 1 | NCT02726711 | Apr 2016 → Dec 2026 expected | multiple system atrophy, orthostatic hypotension | Vanderbilt University | Active not recruiting | No outcome recorded |
| Phase 1 | NCT02425566 | Apr 2015 → Jul 2026 overdue | hypertensive disorder | Vanderbilt University | Active not recruiting | No outcome recorded |
| Phase 1 | NCT02245230 | Jan 2015 → Dec 2023 | essential hypertension | Vanderbilt University | Terminated | No outcome recorded |
| Phase 1 | NCT01137253 | Jun 2010 → Jan 2017 | — | Vanderbilt University | Completed | No outcome recorded |
| Phase 1 | NCT01122407 | Jan 2010 → Nov 2016 | hypertensive disorder, obesity disorder | Vanderbilt University Medical Center | Completed | No outcome recorded |
| Phase 1 | NCT00580619 | Apr 2007 → Jan 2017 | myalgic encephalomeyelitis/chronic fatigue syndrome, orthostatic hypotension, postural orthostatic tachycardia syndrome | Vanderbilt University | Completed | No outcome recorded |
| Phase 1 | NCT00179023 | Apr 2003 → Jan 2017 | hypertensive disorder, obesity disorder, pure autonomic failure | Vanderbilt University | Completed | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT00580957 | Aug 2008 → May 2015 | obesity disorder | Vanderbilt University | Completed | No outcome recorded |
Also used as a comparator or background therapy in 1 trial
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| — | NCT00178919 Background | Aug 2002 → Aug 2008 | hypertensive disorder, pure autonomic failure | Vanderbilt University | Completed | No outcome recorded |
Evidence & citations 9 cited values
Every value below carries the sentence it was read from. 11 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Trimethaphan | “Trimethaphan 4 mg/min IV will be infused for the duration of the study.” NCT00580957 ↗ |
| Known as | Camsilate de trimetaphan | ChEMBL registry synonym — accepted as the source's own label CHEMBL1201329 ↗ |
| Known as | Cansilato de trimetafan | ChEMBL registry synonym — accepted as the source's own label CHEMBL1201329 ↗ |
| Known as | Trimetaphan | ChEMBL registry synonym — accepted as the source's own label CHEMBL1201329 ↗ |
| Known as | Trimethaphan cation | ChEMBL registry synonym — accepted as the source's own label CHEMBL1201329 ↗ |
| Known as | Trimethaphan ion | ChEMBL registry synonym — accepted as the source's own label CHEMBL1201329 ↗ |
| Action | Inhibit | “ganglionic blocker trimethaphan” NCT00179023 ↗ |
| Modality | Small molecule | — CHEMBL1201329 ↗ |
| Route | Intravenous | “IV infusion for the duration of the study at 4-6 mg/min depending on autonomic blockade” NCT00178919 ↗ |