Drugs / ALN-ANG3
last change Jan 2026 re-read 3 minutes ago

ALN-ANG3

Small interfering RNA (siRNA) targets ANGPTL3 via inhibition

Developed for
diabetic kidney disease
Investigated by
Regeneron Pharmaceuticals

Trials 2

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT06452771 Jun 2024 → Dec 2026 expected hypertriglyceridemia 2 Regeneron Pharmaceuticals Active not recruiting No outcome recorded
Phase 21 trial
Phase 2 NCT07271186 Jan 2026 → Sep 2027 expected diabetic kidney disease Regeneron Pharmaceuticals Recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as ALN-ANG3 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06452771 ↗
1

NCT07271186 ↗

Action Inhibit “ANGPTL3 inhibition” NCT07271186 ↗
Modality Small interfering RNA (siRNA) “Small-Interfering RNA” NCT07271186 ↗
Target ANGPTL3 “ANGPTL3 inhibition” NCT07271186 ↗