Drugs / Milk Thistle
Milk Thistle
also known as
Carduus marianus · Milk Thistle Extract · Milk Thistle Extract: Siliphos · silibin · Silymarin
Trials 6 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT01239095 | Jul 2011 → Feb 2023 | colon carcinoma | Richard Whelan | Terminated | No outcome recorded |
| Phase 24 trials | ||||||
| Phase 2 | NCT06477146 | Dec 2024 → Jan 2029 expected | NAFLD1 | University Hospitals Cleveland Medical Center | Recruiting | No outcome recorded |
| Phase 2 | NCT05343780 | May 2019 → Feb 2022 | metabolic dysfunction-associated steatohepatitis | Natural Wellness Egypt | Completed | No outcome recorded |
| Phase 2 | NCT02843451 | Oct 2016 → Oct 2023 | body dysmorphic disorder | University of Chicago | Withdrawn | No outcome recorded |
| Phase 2 | NCT02775448 | Feb 2016 → Aug 2017 | hyperlipidemia, obesity disorder | Hospital Nacional Homeopático, Mexico | Terminated | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT00160901 | Aug 2003 → Dec 2005 | breast cancer | Heidelberg University | Completed | No outcome recorded |
Evidence & citations 8 cited values
Every value below carries the sentence it was read from. 6 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Milk Thistle | “hepatoprotective effect of Heptex® capsules containing 200 mg of Dukung Anak (a powdered extract from aerial parts of Phyllanthus niruri) and 100 mg of Milk Thistle (a powdered...” PMID 39789561 ↗ Jan 2025 |
| Known as | Carduus marianus | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02775448 ↗ |
| Known as | Milk Thistle Extract | “Milk Thistle Extract: Siliphos” NCT01239095 ↗ |
| Known as | Milk Thistle Extract: Siliphos | “Milk Thistle Extract: Siliphos” NCT01239095 ↗ |
| Known as | silibin | “milk thistle (silibin 280 mg/d)” NCT00160901 ↗ |
| Known as | Silymarin | “silymarin (milk thistle)” NCT02843451 ↗ |
| Modality | Traditional medicine (herbal / TCM) | “a herbal medicinal product of Phyllanthus niruri and Silybum marianum powdered extracts (Heptex®)” PMID 39789561 ↗ Jan 2025 |
| Route | Oral | “daily oral medication consisting of selenium (sodium-selenit 100 microg/d), milk thistle” NCT00160901 ↗ |