drugset / Trial / NCT06477146

Milk Thistle Clinical Trial in Pediatric NAFLD

NCT06477146

Phase 2 Recruiting 20 enrolled University Hospitals Cleveland Medical Center
RandomizedParallel-groupDouble-blindTreatment

Summary

Pediatric Fatty Liver disease is a growing problem in the United States and is expected to be the leading cause of Liver Transplantation in Adults in 20 years. Following lifestyle changes such as diet restrictions and exercise may be difficult to consistently maintain. The purpose of this study is to investigate alternative medical therapy with an herbal supplement called Milk Thistle (MT) which may improve fatty liver disease and would be easier to follow than diet and exercise.

Timeline

Start
2024-12-19
Primary completion
2029-01-31
Completion
2029-01-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Milk Thistle Traditional medicine (herbal / TCM) 300 mg Oral
Subject Milk Thistle Traditional medicine (herbal / TCM) 600 mg Oral

Indications