Drugs / PF-03715455
last change May 2015 re-read 2 minutes ago

PF-03715455

also known as Pf-3715455

Small molecule targets MAPK14 via inhibition

Developed for
chronic obstructive pulmonary disease · asthma
Investigated by
Pfizer

Trials 3 · a red edge is where a trial was stopped

20112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT01314885 Jan → Dec 2011 chronic obstructive pulmonary disease Pfizer Completed No outcome recorded
Phase 22 trials
Phase 2 NCT02366637 Jan → May 2015 chronic obstructive pulmonary disease Pfizer Terminated No outcome recorded
Phase 2 NCT02219048 Nov 2014 → May 2015 asthma Pfizer Terminated No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT01186757 Comparator Aug 2010 → Jan 2011 Pfizer Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as PF-03715455 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02366637
3

NCT01186757

NCT02219048

NCT01314885

Known as Pf-3715455 ChEMBL registry synonym — accepted as the source's own label CHEMBL1938400
Action Inhibit “MAP kinase p38 alpha inhibitor” CHEMBL1938400
Modality Small molecule CHEMBL1938400
Route Inhaled “Multiple Inhaled Doses of PF-03715455” NCT01186757
Target MAPK14 “MAP kinase p38 alpha inhibitor” CHEMBL1938400