Drugs / AB-205
last change Jan 2025 re-read 3 minutes ago

AB-205

Cell therapy

Developed for
Hodgkins lymphoma · non-Hodgkin lymphoma
Investigated by
Angiocrine Bioscience · California Institute for Regenerative Medicine (CIRM)

Trials 2

2020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT03925935 May 2019 → Nov 2020 Hodgkins lymphoma, non-Hodgkin lymphoma Angiocrine Bioscience Completed No outcome recorded
Phase 31 trial
Phase 3 NCT05181540 Feb 2022 → Dec 2023 Hodgkins lymphoma, non-Hodgkin lymphoma Angiocrine Bioscience Terminated No outcome recorded

News releases announcing trial results or a regulatory action · 2

DateIssuerRelease
2021-02-08 Angiocrine Bioscience Results Results of an Open Label Dose Escalation Trial of AB-205 (E-CEL® cells) in Adults with Lymphoma Undergoing High-Dose Therapy and Autologous Hematopoietic Cell Transplantation (HDT-AHCT) angiocrinebioscience.com ↗
AB-205 is an experimental engineered-cell therapy designed to accelerate regeneration of organs and eliminate or reduce SRRT.
2020-12-05 Angiocrine Bioscience Results Results of a Phase 1 Open Label Dose Escalation Trial of AB-205 (Allogeneic Engineered Endothelial Cell Therapy) in Adults with Lymphoma Undergoing High-Dose Therapy and Autologous Hematopoietic Cell Transplantation (HDT-AHCT) angiocrinebioscience.com ↗
Here we report results of a Phase I study of AB-205 in adults with lymphoma undergoing HDT-AHCT.

All press releases naming this drug 5 releases

DateIssuerRelease

Evidence & citations 2 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as AB-205 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03925935 ↗
1

NCT05181540 ↗

Modality Cell therapy “Engineered human umbilical vein endothelial cells” NCT03925935 ↗