Drugs / MK-0893
last change Nov 2009 re-read 2 minutes ago

MK-0893

Small molecule targets GCGR via inhibition

Developed for
type 2 diabetes mellitus
Investigated by
Merck Sharp & Dohme LLC

Trials 5 · a red edge is where a trial was stopped

20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT00902161 May → Oct 2009 type 2 diabetes mellitus Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 1 NCT02012166 Jul → Dec 2005 type 2 diabetes mellitus Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 23 trials
Phase 2 NCT00631488 Feb 2008 → Jan 2009 type 2 diabetes mellitus Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 2 NCT00479466 Jul 2007 → May 2008 type 2 diabetes mellitus Merck Sharp & Dohme LLC Terminated No outcome recorded
Phase 2 NCT02004886 Aug 2006 → Feb 2007 type 2 diabetes mellitus Merck Sharp & Dohme LLC Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as MK0893 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00902161
4

NCT00631488

NCT02004886

NCT00479466

NCT02012166

Action Inhibit “Glucagon receptor antagonist” CHEMBL1933349
Modality Small molecule CHEMBL1933349
Route Oral “MK0893 taken orally once daily” NCT00479466
Target GCGR “Glucagon receptor antagonist” CHEMBL1933349