Drugs / MK-0893
last change Nov 2009 re-read 9 days ago

MK-0893

Small molecule targets GCGR via inhibition

Developed for
type 2 diabetes mellitus
Investigated by
Merck Sharp & Dohme LLC

Trials 5

20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials · 1 met primary
Phase 1 NCT00902161 May → Oct 2009 type 2 diabetes mellitus Merck Sharp & Dohme LLC Completed Met primary
Phase 1 NCT02012166 Jul → Dec 2005 type 2 diabetes mellitus Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 23 trials · 2 met primary
Phase 2 NCT00631488 Feb 2008 → Jan 2009 type 2 diabetes mellitus Merck Sharp & Dohme LLC Completed Mixed
Phase 2 NCT00479466 Jul 2007 → May 2008 type 2 diabetes mellitus Merck Sharp & Dohme LLC Terminated Met primary
Phase 2 NCT02004886 Aug 2006 → Feb 2007 type 2 diabetes mellitus Merck Sharp & Dohme LLC Completed Met primary

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as MK-0893 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02004886 ↗
4

NCT02012166 ↗

NCT00631488 ↗

NCT00479466 ↗

NCT00902161 ↗

Action Inhibit “Glucagon receptor antagonist” CHEMBL1933349 ↗
Modality Small molecule — CHEMBL1933349 ↗
Route Oral “MK0893 taken orally once daily” NCT00479466 ↗
Target GCGR “Glucagon receptor antagonist” CHEMBL1933349 ↗