Drugs / Bethanechol
Bethanechol
also known as
bethanechol chloride · Duvoid · Myocholine · Myotonachol · Myotonine · NSC-30783 · Ucholine · Urecholine
Small molecule targets CHRM2, CHRM3 via activation
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | URECHOLINE | — | 1948-10-12 | fda.gov ↗ |
Trials 6
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| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 01 trial | ||||||
| Phase 0 | NCT03572283 | Apr 2018 → Jul 2023 | malignant pancreatic neoplasm | Columbia University | Completed | No outcome recorded |
| Phase 12 trials | ||||||
| Phase 1 | NCT01434901 | Aug 2011 → Jul 2014 | type 2 diabetes mellitus | Washington University School of Medicine | Completed | No outcome recorded |
| Phase 1 | NCT01031043 | Nov 2009 → Apr 2012 | dyskinesia of esophagus | Augusta University | Completed | No outcome recorded |
| Phase 22 trials | ||||||
| Phase 2 | NCT05241249 | Feb 2022 → Jan 2026 overdue | malignant pancreatic neoplasm | Susan E. Bates | Recruiting | No outcome recorded |
| Phase 2 | NCT02058537 | Feb → Jul 2014 | eosinophilic esophagitis | University of Iowa | Terminated | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT02910596 | Oct 2016 → Mar 2017 | urinary bladder disorder | Department of Medical Services Ministry of Public Health of Thailand | Completed | No outcome recorded |
Press releases naming this drug 1 release
| Date | Issuer | Release |
|---|---|---|
| 2006-11-03 | Impax Laboratories, LLC | IMPAX Receives FDA Approval for Generic Versions of Urecholine(R) Tablets amneal.com ↗ |
Evidence & citations 14 cited values
Every value below carries the sentence it was read from. 7 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Bethanechol | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02058537 ↗ |
| Known as | bethanechol chloride | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02910596 ↗ |
| Known as | Duvoid | ChEMBL registry synonym — accepted as the source's own label CHEMBL1482 ↗ |
| Known as | Myocholine | ChEMBL registry synonym — accepted as the source's own label CHEMBL1482 ↗ |
| Known as | Myotonachol | ChEMBL registry synonym — accepted as the source's own label CHEMBL1482 ↗ |
| Known as | Myotonine | ChEMBL registry synonym — accepted as the source's own label CHEMBL1482 ↗ |
| Known as | NSC-30783 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1482 ↗ |
| Known as | Ucholine | “Ucholine(Bethanechol chloride, 10 mg) 2 tablets oral tid, ac Start on 3rd - 5th postoperative day” NCT02910596 ↗ |
| Known as | Urecholine | ChEMBL registry synonym — accepted as the source's own label CHEMBL1482 ↗ |
| Action | Activate | “Muscarinic acetylcholine receptor M2 agonist” CHEMBL1482 ↗2“Muscarinic acetylcholine receptor M3 agonist” CHEMBL1482 ↗ “Bethanechol, a Muscarinic Agonist” NCT01434901 ↗ |
| Modality | Small molecule | — CHEMBL1482 ↗ |
| Route | Other | “Administration will be performed by throat spray device” NCT01031043 ↗ |
| Target | CHRM2 | “Muscarinic acetylcholine receptor M2 agonist” CHEMBL1482 ↗ |
| Target | CHRM3 | “Muscarinic acetylcholine receptor M3 agonist” CHEMBL1482 ↗ |