Drugs / YL-17231
last change Apr 2026 re-read 3 minutes ago

YL-17231

targets KRAS via inhibition

Developed for
cancer · neoplasm
Investigated by
Shanghai YingLi Pharmaceutical Co. Ltd.

Trials 2

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT06096974 Oct 2023 → Oct 2025 overdue cancer Shanghai YingLi Pharmaceutical Co. Ltd. Recruiting No outcome recorded
Phase 1 NCT06078800 Sep 2023 → Mar 2025 neoplasm Shanghai YingLi Pharmaceutical Co. Ltd. Unknown No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2023-07-07 280Bio, Inc. Regulatory 280Bio receives IND approval from the FDA for YL-17231 280bio.com ↗
280Bio, Inc. a clinical stage biotechnology company focused on the development of precision oncology medicines, today announced that the U.S. Food and Drug Administration (FDA) has granted the company’s Investigational New Drug (IND) application for the investigational drug YL-17231, a small molecule inhibitor of RAS signaling.

All press releases naming this drug 1 release

DateIssuerRelease

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as YL-17231 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06096974 ↗
1

NCT06078800 ↗

Action Inhibit “Pan-KRAS Inhibitor YL-17231” NCT06078800 ↗
Route Oral “eligible patients will receive oral YL-17231 once or twice daily” NCT06078800 ↗
Target KRAS “Pan-KRAS Inhibitor YL-17231” NCT06078800 ↗