drugset / Trial / NCT06096974

Pan-RAS Inhibitor YL-17231 in Patients With Advanced Solid Tumors Harboring Mutations in KRAS, HRAS, or NRAS

NCT06096974 ↗

Phase 1 Recruiting 60 enrolled Shanghai YingLi Pharmaceutical Co. Ltd.
NaSequentialOpen-labelTreatment

Summary

This study will evaluate the safety, tolerability, drug levels, pharmacodynamic effects, and clinical activity of YL 17231 in patients with advanced solid tumors harboring mutations in KRAS, HRAS, or NRAS.

Timeline

Start
2023-10-24
Primary completion
2025-10
Completion
2026-04

Drugs

EvaluationDrugModalityDoseRoute
Subject YL-17231 Unknown 0.25 mg Oral

Indications