Drugs / V116
last change Mar 2025 re-read 2 minutes ago

V116

Vaccine

Developed for
pneumococcal infection · streptococcal pneumonia
Investigated by
Merck Sharp & Dohme LLC

Trials 11 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT04665050 Feb → Apr 2021 pneumococcal infection Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT04168190 Dec 2019 → Jul 2021 streptococcal pneumonia Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 39 trials
Phase 3 NCT06177912 Jan 2024 → Feb 2025 pneumococcal infection Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 3 NCT05696080 Feb 2023 → Feb 2024 pneumococcal infection Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 3 NCT05633992 Jan → May 2023 pneumococcal infection Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 3 NCT05569954 Nov 2022 → Oct 2023 pneumococcal infection Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 3 NCT05526716 Sep 2022 → Jun 2023 streptococcal pneumonia Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 3 NCT05464420 Aug 2022 → May 2023 pneumococcal infection Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 3 NCT05425732 Jul 2022 → May 2023 pneumococcal infection Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 3 NCT05393037 Jul 2022 → Jul 2023 pneumococcal infection Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 3 NCT05420961 Jul 2022 → May 2023 streptococcal pneumonia Merck Sharp & Dohme LLC Completed No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 11 sources stand behind the page.

FieldValueCited text
Known as V116 “Background: V116 is a 21-valent pneumococcal conjugate vaccine (PCV) designed for adults.” PMID 40333240 Mar 2025
10

NCT06177912

NCT05633992

NCT05393037

NCT04168190

NCT05425732

NCT05420961

NCT04665050

NCT05464420

NCT05696080

NCT05526716

Modality Vaccine “Pneumococcal 21-valent conjugate vaccine with 2 μg of each of the following pneumococcal polysaccharides (PnPs) antigen” NCT04665050
Route Intramuscular “a single intramuscular (IM) dose of V116 on Day 1” NCT05393037