drugset / Trial / NCT06177912

A Clinical Study of the V116 Vaccine for Children and Teenagers (V116-013)

NCT06177912

Phase 3 Completed 882 enrolled Merck Sharp & Dohme LLC
RandomizedParallel-groupTriple-blindPrevention

Summary

The purpose of this study is to evaluate the safety, tolerability, and immunogenicity of V116 compared to PPSV23 in children and teenagers 2 through 17 years of age, who had completed routine pneumococcal vaccine as infants/toddlers. Researchers want to learn if V116 is as good as, or is better than the PPSV23 vaccine in terms of the antibody immune response. V116 and PPSV23 will be studied in children and teenagers who have a higher risk of getting pneumococcal disease (PD).

Timeline

Start
2024-01-18
Primary completion
2025-02-26
Completion
2025-02-26

Drugs

EvaluationDrugModalityDoseRoute
Comparator Pneumovax 23 Vaccine 0.5 ml Intramuscular
Subject V116 Vaccine 0.5 ml Intramuscular