Drugs / Primidone
Primidone
also known as
Lepimidin · Lepsiral · Liskantin · Mysoline · NSC-41701 · Primaclone · Primidona · Resimatil
Small molecule targets CYP1A2
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | MYSOLINE | — | 1954-03-08 | fda.gov ↗ |
Trials 1 · a red edge is where a trial was stopped
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| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 2 | NCT02008123 | Aug 2013 → Dec 2017 | — | Dent Neuroscience Research Center | Withdrawn | No outcome recorded |
Also used as a comparator or background therapy in 1 trial
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1 | NCT00734864 Background | Jun 2009 → Jun 2010 | anaplastic astrocytoma, anaplastic oligodendroglioma, gliosarcoma | Annick Desjardins | Withdrawn | No outcome recorded |
Evidence & citations 11 cited values
Every value below carries the sentence it was read from. 3 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Primidone | “Primidone/Mysoline” NCT00734864 ↗ |
| Known as | Lepimidin | ChEMBL registry synonym — accepted as the source's own label CHEMBL856 ↗ |
| Known as | Lepsiral | ChEMBL registry synonym — accepted as the source's own label CHEMBL856 ↗ |
| Known as | Liskantin | ChEMBL registry synonym — accepted as the source's own label CHEMBL856 ↗ |
| Known as | Mysoline | “Primidone/Mysoline” NCT00734864 ↗ |
| Known as | NSC-41701 | ChEMBL registry synonym — accepted as the source's own label CHEMBL856 ↗ |
| Known as | Primaclone | ChEMBL registry synonym — accepted as the source's own label CHEMBL856 ↗ |
| Known as | Primidona | ChEMBL registry synonym — accepted as the source's own label CHEMBL856 ↗ |
| Known as | Resimatil | ChEMBL registry synonym — accepted as the source's own label CHEMBL856 ↗ |
| Modality | Small molecule | — CHEMBL856 ↗ |
| Target | CYP1A2 | “primidone will be used to induce CYP 1A2” NCT02008123 ↗ |