Effect of Primidone on Platelet Responsiveness in Patients Determined to be Clopidogrel Resistant

Summary

The purpose of this study is to determine whether adding primidone will improve the metabolism of clopidogrel thereby increasing metabolite levels within the blood stream and platelet response to clopidogrel in patients who were previously found to lack adequate response to clopidogrel. This information could help overcome clopidogrel resistance in patients who are at risk for stroke or transient ischemic attack (TIA).

Timeline

Start

2013-08

Primary completion

2017-12

Completion

—

Outcome

Outcome not reported

Stopped (Enrollment): “Inclusion/Exclusion criteria was too stringent to enroll patients at this site.”

Drugs

Indications

No indication recorded.