drugset / Trial / NCT02008123
Effect of Primidone on Platelet Responsiveness in Patients Determined to be Clopidogrel Resistant
NaSingle-groupOpen-labelTreatment
Summary
The purpose of this study is to determine whether adding primidone will improve the metabolism of clopidogrel thereby increasing metabolite levels within the blood stream and platelet response to clopidogrel in patients who were previously found to lack adequate response to clopidogrel. This information could help overcome clopidogrel resistance in patients who are at risk for stroke or transient ischemic attack (TIA).
Timeline
- Start
- 2013-08
- Primary completion
- 2017-12
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Primidone | Small molecule | 250 mg | — |
Indications
No indication recorded.