drugset / Trial / NCT02008123

Effect of Primidone on Platelet Responsiveness in Patients Determined to be Clopidogrel Resistant

NCT02008123

NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to determine whether adding primidone will improve the metabolism of clopidogrel thereby increasing metabolite levels within the blood stream and platelet response to clopidogrel in patients who were previously found to lack adequate response to clopidogrel. This information could help overcome clopidogrel resistance in patients who are at risk for stroke or transient ischemic attack (TIA).

Timeline

Start
2013-08
Primary completion
2017-12
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Primidone Small molecule 250 mg

Indications

No indication recorded.