Drugs / Cyclizine
Cyclizine
also known as
Ciclizina · Cyclizine hcl · CYCLIZINE HYDROCHLORIDE · Marzine · NSC-169102 · NSC-26608
Small molecule targets HRH1 via inhibition
Trials 0
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Comparator or background therapy3 trials | ||||||
| Phase 4 | NCT02009306 Background | Jan 2017 → Feb 2018 | — | Gloucestershire Hospitals NHS Foundation Trust | Completed | No outcome recorded |
| — | NCT03931135 Comparator | Sep 2019 → Oct 2020 | — | Assiut University | Unknown | No outcome recorded |
| — | NCT02288923 Comparator | Mar 2015 → Jul 2018 | osteoarthritis, knee | Royal Devon and Exeter NHS Foundation Trust | Completed | No outcome recorded |
Evidence & citations 11 cited values
Every value below carries the sentence it was read from. 4 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Cyclizine | “They will be prescribed 50mg cyclizine as an addition to this if needed.” NCT02288923 ↗ |
| Known as | Ciclizina | ChEMBL registry synonym — accepted as the source's own label CHEMBL648 ↗ |
| Known as | Cyclizine hcl | ChEMBL registry synonym — accepted as the source's own label CHEMBL648 ↗ |
| Known as | CYCLIZINE HYDROCHLORIDE | ChEMBL registry synonym — accepted as the source's own label CHEMBL648 ↗ |
| Known as | Marzine | ChEMBL registry synonym — accepted as the source's own label CHEMBL648 ↗ |
| Known as | NSC-169102 | ChEMBL registry synonym — accepted as the source's own label CHEMBL648 ↗ |
| Known as | NSC-26608 | ChEMBL registry synonym — accepted as the source's own label CHEMBL648 ↗ |
| Action | Inhibit | “Cyclizine: a histamine H1 antagonist given by mouth or parenterally for control of postoperative and drug-induced nausea and vomiting and in motion sickness.” NCT03931135 ↗1“Histamine H1 receptor antagonist” CHEMBL648 ↗ |
| Modality | Small molecule | — CHEMBL648 ↗ |
| Route | Intravenous | “IV Cyclizine versus IV Dexamethasone” NCT03931135 ↗ |
| Target | HRH1 | “Histamine H1 receptor antagonist” CHEMBL648 ↗ |