Drugs / AZD5312
last change Jan 2023 re-read 2 minutes ago

AZD5312

also known as ARRx · ISIS-ARRX · ISIS-AZ1RX

targets AR via inhibition

Developed for
prostate cancer
Investigated by
AstraZeneca · National Cancer Institute (NCI) · University of Michigan Rogel Cancer Center

Trials 2 · a red edge is where a trial was stopped

2015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT03300505 May 2019 → Jan 2023 prostate cancer University of Michigan Rogel Cancer Center Terminated No outcome recorded
Phase 1 NCT02144051 May 2014 → Mar 2016 AstraZeneca Completed No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as AZD5312 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02144051
Known as ARRx ClinicalTrials.gov intervention name — accepted as the source's own label NCT03300505
Known as ISIS-ARRX ChEMBL registry synonym — accepted as the source's own label CHEMBL4297901
Known as ISIS-AZ1RX ChEMBL registry synonym — accepted as the source's own label CHEMBL4297901
Action Inhibit “specifically suppressing human Androgen Receptor (AR) expression” NCT02144051
Modality Antisense oligonucleotide “generation 2.5 antisense oligonucleotide (ASO)” NCT02144051
Route Intravenous “AZD5312 will be given intravenously (IV) as an infusion” NCT02144051
Target AR “suppressing human Androgen Receptor (AR) expression” NCT02144051