Drugs / Dimethyltryptamine
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Dimethyltryptamine

also known as DMT · N,N-dimethyltryptamine · VLS-01
Developed for
alcohol-related disorders · major depressive disorder
Investigated by
Johns Hopkins University · University Hospital, Basel, Switzerland · atai Therapeutics, Inc.

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT06772753 Feb 2025 → Jun 2027 expected Johns Hopkins University Recruiting No outcome recorded
Phase 1 NCT04353024 Jun 2021 → Aug 2022 University Hospital, Basel, Switzerland Completed No outcome recorded
Phase 21 trial
Phase 2 NCT06524830 Dec 2024 → Aug 2026 overdue atai Therapeutics, Inc. Recruiting No outcome recorded
Also used as a comparator or background therapy in 2 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT06070649 Comparator Aug 2025 → Aug 2026 overdue alcohol-related disorders Yale University Recruiting No outcome recorded
Phase 1 NCT04711915 Comparator Mar 2021 → Jul 2026 overdue major depressive disorder Yale University Active not recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as Dimethyltryptamine ClinicalTrials.gov intervention name — accepted as the source's own label NCT06070649
3

NCT04711915

NCT06772753

NCT04353024

Known as DMT “N,N-dimethyltryptamine (DMT) is a naturally-occurring psychedelic substance widely used in recreational and spiritual settings.” NCT04353024
3

“the psychedelic dimethyltryptamine (DMT), in addition to a short course of psychotherapy, on Alcohol Use Disorder (AUD).” NCT06070649

“0.1 mg/kg Dimethyltryptamine (DMT)” NCT04711915

“Drug: Dimethyltryptamine (DMT)” NCT06772753

Known as N,N-dimethyltryptamine N,N-dimethyltryptamine (DMT) is a naturally-occurring psychedelic substance widely used in recreational and spiritual settings.” NCT04353024
Known as VLS-01 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06524830
Route Intravenous Intravenous DMT bolus and/or DMT maintenance perfusion over 90 min” NCT04353024