Drugs / Dimethyltryptamine
last change Aug 2026 re-read 9 days ago

Dimethyltryptamine

also known as DMT · N,N-dimethyltryptamine · VLS-01
Developed for
alcohol-related disorders · major depressive disorder
Investigated by
Johns Hopkins University · University Hospital, Basel, Switzerland · atai Therapeutics, Inc.

Trials 3

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT06772753 Feb 2025 → Jun 2027 expected — Johns Hopkins University Recruiting No outcome recorded
Phase 1 NCT04353024 Jun 2021 → Aug 2022 — University Hospital, Basel, Switzerland Completed No outcome recorded
Phase 21 trial
Phase 2 NCT06524830 Dec 2024 → Aug 2026 overdue — atai Therapeutics, Inc. Recruiting No outcome recorded
Comparator or background therapy2 trials
Phase 1 NCT06070649 Comparator Aug 2025 → Aug 2027 expected alcohol-related disorders Yale University Recruiting No outcome recorded
Phase 1 NCT04711915 Comparator Mar 2021 → Jul 2026 overdue major depressive disorder Yale University Active not recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as Dimethyltryptamine ClinicalTrials.gov intervention name — accepted as the source's own label NCT04711915 ↗
3

NCT04353024 ↗

NCT06070649 ↗

NCT06772753 ↗

Known as DMT “N,N-dimethyltryptamine (DMT) is a naturally-occurring psychedelic substance widely used in recreational and spiritual settings.” NCT04353024 ↗
3

“the psychedelic dimethyltryptamine (DMT), in addition to a short course of psychotherapy, on Alcohol Use Disorder (AUD).” NCT06070649 ↗

“0.1 mg/kg Dimethyltryptamine (DMT)” NCT04711915 ↗

“Drug: Dimethyltryptamine (DMT)” NCT06772753 ↗

Known as N,N-dimethyltryptamine “N,N-dimethyltryptamine (DMT) is a naturally-occurring psychedelic substance widely used in recreational and spiritual settings.” NCT04353024 ↗
Known as VLS-01 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06524830 ↗
Route Intravenous “Intravenous DMT bolus and/or DMT maintenance perfusion over 90 min” NCT04353024 ↗