drugset / Trial / NCT06070649
The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)
Phase 1
Recruiting
63 enrolled
Yale University
National Institute on Alcohol Abuse and Alcoholism (NIAAA) · collab
RandomizedParallel-groupDouble-blindOther
Summary
This proposed study is a double-blind, randomized, placebo-controlled, parallel-group, laboratory study to determine the effects of DMT, plus psychotherapy, on Alcohol Use Disorder.
Timeline
- Start
- 2025-08-04
- Primary completion
- 2026-08-01
- Completion
- 2026-08-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dimethyltryptamine | Unknown | 0.01 mg/kg | Other |
| Comparator | Dimethyltryptamine | Unknown | 0.3 mg/kg | Other |
| Comparator | Diphenhydramine | Unknown | 25 mg | Other |