Drugs / Taurine
last change May 2026 re-read 2 minutes ago

Taurine

also known as VIZILOTON

Other / unclassified

Developed for
diabetes mellitus · long COVID-19 · mucositis · bipolar I disorder · cataract · cognitive disorder · homocystinuria · ischemic stroke
+11 more · peripartum cardiomyopathy · peripheral arterial disease · psychotic disorder · radiodermatitis · relapsing-remitting multiple sclerosis · bipolar depression · chronic periodontitis · hyperglycemia · hypertensive disorder · manic bipolar affective disorder · type 2 diabetes mellitus
Investigated by
Canadian Institutes of Health Research (CIHR) · Stanley Medical Research Institute · Third Military Medical University · University of Alberta · Affiliated Hospital of North Sichuan Medical College · Ain Shams University
+23 more · Beijing Tiantan Hospital · Cambridge Health Alliance · Daewoong Pharmaceutical Co. LTD. · Daping Hospital of Army Medical University · First Affiliated Hospital of Chongqing Medical University · First Affiliated Hospital of Kunming Medical University · Lanzhou University Second Hospital · Mclean Hospital · Melbourne Health · Nanjing Yoko Biomedical Co., Ltd. · Riyadh Colleges of Dentistry and Pharmacy · Shandong Provincial Hospital · Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University · Sichuan Academy of Medical Sciences · Southern Health · Sun Yat-sen University · Tang-Du Hospital · The Affiliated Hospital of Inner Mongolia Medical University · The First Affiliated Hospital of Hainan Medical University · The People's Hospital of Leshan · University Health Network, Toronto · University Of Anbar · University of Colorado, Denver

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved EU (EMA) Maapliv 2025-07-28 europa.eu

Trials 15 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00391001 Feb 2006 → Aug 2007 bipolar I disorder Cambridge Health Alliance Terminated No outcome recorded
Phase 1/23 trials
Phase 1/2 NCT07682402 Sep 2026 → Mar 2028 expected long COVID-19 University of Alberta Not yet recruiting No outcome recorded
Phase 1/2 NCT06639711 Jul 2023 → Dec 2024 overdue cataract University Of Anbar Active not recruiting No outcome recorded
Phase 1/2 NCT01192828 Jan 2010 → Dec 2017 homocystinuria University of Colorado, Denver Completed No outcome recorded
Phase 24 trials
Phase 2 NCT07567742 May 2026 → Mar 2027 expected mucositis, nasopharyngeal carcinoma Sun Yat-sen University Not yet recruiting No outcome recorded
Phase 2 NCT07263607 Jan 2026 → Jul 2029 expected relapsing-remitting multiple sclerosis Sichuan Academy of Medical Sciences Not yet recruiting No outcome recorded
Phase 2 NCT07029178 Nov 2025 → Nov 2027 expected mucositis, radiodermatitis Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University Recruiting No outcome recorded
Phase 2 NCT04984577 Nov 2021 → Dec 2026 ischemic stroke Nanjing Yoko Biomedical Co., Ltd. Suspended No outcome recorded
Phase 2/33 trials
Phase 2/3 NCT06721949 Nov 2025 → Feb 2028 expected long COVID-19 University of Alberta Recruiting No outcome recorded
Phase 2/3 NCT03907267 Jan 2015 → Dec 2019 peripartum cardiomyopathy Ain Shams University Completed No outcome recorded
Phase 2/3 NCT00420823 Jan 2007 → Dec 2009 psychotic disorder Melbourne Health Completed No outcome recorded
Phase 42 trials
Phase 4 NCT02418130 Oct 2014 → Mar 2015 Daewoong Pharmaceutical Co. LTD. Completed No outcome recorded
Phase 4 NCT02535143 Sep → Dec 2014 Riyadh Colleges of Dentistry and Pharmacy Completed No outcome recorded
Phase not applicable2 trials
NCT03410173 Jan 2017 → Jun 2018 cognitive disorder, diabetes mellitus Third Military Medical University Unknown No outcome recorded
NCT03410537 Jan 2017 → Jun 2018 diabetes mellitus, peripheral arterial disease Third Military Medical University Unknown No outcome recorded
Also used as a comparator or background therapy in 5 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT01226537 Comparator Nov 2012 → Nov 2013 hyperglycemia Hamad Medical Corporation Unknown No outcome recorded
Phase 22 trials
Phase 2 NCT04874012 Comparator Jun 2021 → Oct 2025 overdue type 2 diabetes mellitus Hospital de Clinicas de Porto Alegre Recruiting No outcome recorded
Phase 2 NCT00217165 Comparator Apr 2005 → Jan 2010 bipolar depression, manic bipolar affective disorder Mclean Hospital Completed No outcome recorded
Phase 31 trial
Phase 3 NCT01816698 Comparator Dec 2012 → Mar 2015 hypertensive disorder Zhiming Zhu Completed No outcome recorded
Phase not applicable1 trial
NCT04772508 Comparator Dec 2020 → Mar 2021 chronic periodontitis Maharishi Markendeswar University (Deemed to be University) Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 21 sources stand behind the page.

FieldValueCited text
Known as taurine “Compound Edaravone Injection 30mg/dose (Edaravone 30mg, Taurine 600 mg), one dose every 12 hours, continue for 14 days” NCT04984577
19

NCT01192828

NCT04772508

NCT02535143

NCT07682402

NCT03907267

NCT04874012

NCT00217165

NCT01226537

NCT01816698

NCT00391001

NCT03410537

NCT07029178

NCT03410173

NCT00420823

NCT06721949

NCT07567742

NCT02418130

NCT07263607

NCT06639711

Known as VIZILOTON “available under brand name VIZILOTONNCT06639711
Action Inhibit inhibits the N-methyl-D-aspartate receptor” PMID 27835719 Dec 2016
Modality Other / unclassified “Taurine is an amino acid” NCT00217165
Route Oral “taurine 2mg BID po” NCT00217165