Drugs / Taurine
last change 11 days ago re-read 9 days ago

Taurine

also known as VIZILOTON

Other / unclassified

Developed for
diabetes mellitus · long COVID-19 · mucositis · bipolar I disorder · cataract · cognitive disorder · homocystinuria · ischemic stroke
+11 more · peripartum cardiomyopathy · peripheral arterial disease · psychotic disorder · radiodermatitis · relapsing-remitting multiple sclerosis · bipolar depression · chronic periodontitis · hyperglycemia · hypertensive disorder · manic bipolar affective disorder · type 2 diabetes mellitus
Investigated by
Canadian Institutes of Health Research (CIHR) · Stanley Medical Research Institute · Third Military Medical University · University of Alberta · Affiliated Hospital of North Sichuan Medical College · Ain Shams University
+23 more · Beijing Tiantan Hospital · Cambridge Health Alliance · Daewoong Pharmaceutical Co. LTD. · Daping Hospital of Army Medical University · First Affiliated Hospital of Chongqing Medical University · First Affiliated Hospital of Kunming Medical University · Lanzhou University Second Hospital · Mclean Hospital · Melbourne Health · Nanjing Yoko Biomedical Co., Ltd. · Riyadh Colleges of Dentistry and Pharmacy · Shandong Provincial Hospital · Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University · Sichuan Academy of Medical Sciences · Southern Health · Sun Yat-sen University · Tang-Du Hospital · The Affiliated Hospital of Inner Mongolia Medical University · The First Affiliated Hospital of Hainan Medical University · The People's Hospital of Leshan · University Health Network, Toronto · University Of Anbar · University of Colorado, Denver

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved EU (EMA) Maapliv — 2025-07-28 europa.eu ↗

Trials 15

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00391001 Feb 2006 → Aug 2007 bipolar I disorder Cambridge Health Alliance Terminated No outcome recorded
Phase 1/23 trials
Phase 1/2 NCT07682402 Sep 2026 → Mar 2028 expected long COVID-19 University of Alberta Not yet recruiting No outcome recorded
Phase 1/2 NCT06639711 Jul 2023 → Dec 2024 overdue cataract University Of Anbar Active not recruiting No outcome recorded
Phase 1/2 NCT01192828 Jan 2010 → Dec 2017 homocystinuria University of Colorado, Denver Completed No outcome recorded
Phase 24 trials
Phase 2 NCT07567742 May 2026 → Mar 2027 expected mucositis, nasopharyngeal carcinoma Sun Yat-sen University Not yet recruiting No outcome recorded
Phase 2 NCT07263607 Jan 2026 → Jul 2029 expected relapsing-remitting multiple sclerosis Sichuan Academy of Medical Sciences Not yet recruiting No outcome recorded
Phase 2 NCT07029178 Nov 2025 → Nov 2027 expected mucositis, radiodermatitis Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University Recruiting No outcome recorded
Phase 2 NCT04984577 Nov 2021 → Dec 2026 ischemic stroke Nanjing Yoko Biomedical Co., Ltd. Suspended No outcome recorded Stop: Business
Phase 2/33 trials
Phase 2/3 NCT06721949 Nov 2025 → Feb 2028 expected long COVID-19 University of Alberta Recruiting No outcome recorded
Phase 2/3 NCT03907267 Jan 2015 → Dec 2019 peripartum cardiomyopathy Ain Shams University Completed No outcome recorded
Phase 2/3 NCT00420823 Jan 2007 → Dec 2009 psychotic disorder Melbourne Health Completed No outcome recorded
Phase 42 trials
Phase 4 NCT02418130 Oct 2014 → Mar 2015 — Daewoong Pharmaceutical Co. LTD. Completed No outcome recorded
Phase 4 NCT02535143 Sep → Dec 2014 — Riyadh Colleges of Dentistry and Pharmacy Completed No outcome recorded
Phase not applicable2 trials
— NCT03410537 Jan 2017 → Jun 2018 diabetes mellitus, peripheral arterial disease Third Military Medical University Unknown No outcome recorded
— NCT03410173 Jan 2017 → Jun 2018 cognitive disorder, diabetes mellitus Third Military Medical University Unknown No outcome recorded
Comparator or background therapy5 trials
Phase 1/2 NCT01226537 Comparator Nov 2012 → Nov 2013 hyperglycemia Hamad Medical Corporation Unknown No outcome recorded
Phase 2 NCT04874012 Comparator Jun 2021 → Dec 2025 overdue type 2 diabetes mellitus Hospital de Clinicas de Porto Alegre Recruiting No outcome recorded
Phase 2 NCT00217165 Comparator Apr 2005 → Jan 2010 bipolar depression, manic bipolar affective disorder Mclean Hospital Completed No outcome recorded
Phase 3 NCT01816698 Comparator Dec 2012 → Mar 2015 hypertensive disorder Zhiming Zhu Completed No outcome recorded
— NCT04772508 Comparator Dec 2020 → Mar 2021 chronic periodontitis Maharishi Markendeswar University (Deemed to be University) Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 21 sources stand behind the page.

FieldValueCited text
Known as Taurine “Compound Edaravone Injection 30mg/dose (Edaravone 30mg, Taurine 600 mg), one dose every 12 hours, continue for 14 days” NCT04984577 ↗
19

NCT03907267 ↗

NCT07029178 ↗

NCT07682402 ↗

NCT07263607 ↗

NCT01816698 ↗

NCT00420823 ↗

NCT02418130 ↗

NCT04772508 ↗

NCT06721949 ↗

NCT01192828 ↗

Show 9 more sources

Known as VIZILOTON “available under brand name VIZILOTON” NCT06639711 ↗
Action Inhibit “inhibits the N-methyl-D-aspartate receptor” PMID 27835719 ↗ Dec 2016
Modality Other / unclassified “Taurine is an amino acid” NCT00217165 ↗
Route Oral “taurine 2mg BID po” NCT00217165 ↗