Drugs / MUC1 Peptide-Poly-ICLC Vaccine
last change Sep 2021 re-read 3 minutes ago

MUC1 Peptide-Poly-ICLC Vaccine

Vaccine targets MUC1 via depletion

Developed for
colorectal carcinoma · colorectal tubulovillous adenoma · lung carcinoma
Investigated by
National Cancer Institute (NCI)

Trials 2

2015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT03300817 Dec 2017 → Sep 2021 overdue lung carcinoma National Cancer Institute (NCI) Active not recruiting No outcome recorded
Phase 21 trial · 1 met primary
Phase 2 NCT02134925 Jun 2014 → Jan 2017 overdue colorectal carcinoma, colorectal tubulovillous adenoma National Cancer Institute (NCI) Active not recruiting Met primary

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as MUC1 Peptide-Poly-ICLC Vaccine ClinicalTrials.gov intervention name — accepted as the source's own label NCT03300817 ↗
1

NCT02134925 ↗

Known as MUC1 peptide vaccine with adjuvant “To compare the immunogenicity at week 12 of a MUC1 peptide vaccine with adjuvant (MUC1 peptide-poly-ICLC adjuvant vaccine) (administered at 0, 2, and 10 weeks)” NCT02134925 ↗
Known as MUC1 peptide-poly-ICLC adjuvant vaccine “This randomized phase II clinical trial studies how well MUC1 peptide-poly-ICLC adjuvant vaccine works in treating patients with newly diagnosed advanced colon polyps...” NCT02134925 ↗
Action Deplete “Vaccines made from peptides may help the body build an effective immune response to kill polyp cells.” NCT02134925 ↗
Modality Vaccine “MUC1 peptide-poly-ICLC adjuvant vaccine” NCT02134925 ↗
Route Subcutaneous “Given SC” NCT02134925 ↗
Target MUC1 “anti-MUC1 antibody response” NCT02134925 ↗