drugset / Trial / NCT03300817

MUC1 Vaccine in Preventing Lung Cancer in Current and Former Smokers at High Risk for Lung Cancer

NCT03300817 ↗

Phase 1 Active not recruiting 50 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelPrevention

Summary

This pilot phase I trial studies the side effects and how well MUC1 peptide-Poly-ICLC vaccine works in preventing lung cancer in current and former smokers at high risk for lung cancer. Vaccines made from peptides may help the body build an effective immune response to kill cells. MUC1 peptide-Poly-ICLC vaccine may stimulate the body's immune system and slow or stop the changes from normal to pre-cancer to cancer.

Timeline

Start
2017-12-27
Primary completion
2021-09-23
Completion
2026-12-01

Drugs

EvaluationDrugModalityDoseRoute
Subject MUC1 Peptide-Poly-ICLC Vaccine Vaccine — Subcutaneous

Indications