Drugs / PACAP38
PACAP38
Trials 4 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| — | NCT07342296 | Feb → Dec 2026 expected | migraine with aura | Danish Headache Center | Not yet recruiting | No outcome recorded |
| — | NCT05378061 | Jun 2022 → Dec 2023 | — | Danish Headache Center | Unknown | No outcome recorded |
| — | NCT02364453 | Feb 2015 → Apr 2016 | migraine without aura | Song Guo | Completed | No outcome recorded |
| — | NCT00380263 | Nov 2006 → Nov 2007 | migraine without aura | Danish Headache Center | Completed | No outcome recorded |
Also used as a comparator or background therapy in 3 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| — | NCT05635604 Comparator | Mar → Aug 2023 | migraine disorder | Danish Headache Center | Completed | No outcome recorded |
| — | NCT04960657 Comparator | Oct 2020 → Mar 2021 | migraine disorder | Danish Headache Center | Completed | No outcome recorded |
| — | NCT01471990 Comparator | May 2011 → Jun 2012 | migraine without aura | Glostrup University Hospital, Copenhagen | Completed | No outcome recorded |
Evidence & citations 5 cited values
Every value below carries the sentence it was read from. 8 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | PACAP-38 | “The purpose of this study is to examine and compare the effect of pituitary adenylate cyclase-activating polypeptide-38 (PACAP38) and vasoactive intestinal polypeptide (VIP) on...” NCT01471990 ↗6“Calcitonin gene-related peptide (CGRP) and pituitary adenylate cyclase-activating polypeptide-38 (PACAP38) are key pathogenic drivers of migraine.” PMID 40229719 ↗ Apr 2025 “Pituitary Adenylate Cyclase Activating Polypeptide-38 (PACAP-38)” NCT07342296 ↗ |
| Known as | Pituitary Adenylate Cyclase-Activating Polypeptide | “PACAP38´s (Pituitary Adenylate Cyclase-Activating Polypeptide) Headache Inducing Characteristics and Effects on the Cerebral Blood Flow” NCT00380263 ↗ |
| Known as | Pituitary Adenylate Cyclase-Activating Polypeptide-38 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01471990 ↗ |
| Modality | Peptide | “pituitary adenylate cyclase-activating polypeptide-38 (PACAP38)” NCT01471990 ↗ |
| Route | Other | “after infusion of PACAP38” NCT02364453 ↗ |