Drugs / AZD8848
Trials 9
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 17 trials | ||||||
| Phase 1 | NCT01818869 | Jan → Feb 2014 | — | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT01560234 | May 2012 → Jul 2014 | — | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT01203124 | Nov 2010 → Mar 2011 | — | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT01205867 | Sep 2010 → Feb 2011 | butyrylcholinesterase deficiency | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT00925678 | Jun 2009 → ? | allergic rhinitis | Sumitomo Pharma Co., Ltd. | Completed | No outcome recorded |
| Phase 1 | NCT00770003 | Sep 2008 → Mar 2009 | allergic rhinitis | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT00688779 | Jan → May 2008 | allergic rhinitis | AstraZeneca | Completed | No outcome recorded |
| Phase 22 trials · 1 met primary | ||||||
| Phase 2 | NCT01185080 | Sep → Dec 2010 | allergic rhinitis | AstraZeneca | Completed | No outcome recorded |
| Phase 2 | NCT00999466 | Oct 2009 → Feb 2011 | allergic asthma | AstraZeneca | Completed | Met primary |
Evidence & citations 6 cited values
Every value below carries the sentence it was read from. 11 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | AZD8848 | “A Toll-like receptor 7 (TLR7) agonist (AZD8848)” PMID 26342289 ↗ Sep 2015 |
| Known as | DSP-3025 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00925678 ↗ |
| Action | Activate | “A Toll-like receptor 7 agonist such as AZD8848 may have potential as a treatment for allergic airway disease by skewing the immune system away from a Th2 profile.” PMID 22726593 ↗ Jun 2012 |
| Modality | Small molecule | — CHEMBL4297356 ↗ |
| Route | Intranasal | “single dose intranasal administration of AZD8848” NCT00688779 ↗ |
| Target | TLR7 | “Plasma interleukin-1 receptor antagonist was elevated after administration of AZD8848, reflecting interferon production secondary to TLR7 stimulation.” PMID 22726593 ↗ Jun 2012 |