To Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Doses AZD8848 in Healthy Subjects

Phase 1 Completed 8 enrolled AstraZeneca

RandomizedParallel-groupDouble-blindBasic science

Summary

This study will investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of multiple ascending doses of AZD8848 in healthy subjects.

Timeline

Start: 2014-01
Primary completion: 2014-02
Completion: 2014-02

Publications

Delaney S, Biffen M, Maltby J, Bell J, Asimus S, Aggarwal A, Kraan M, Keeling D. Tolerability in man following inhalation dosing of the selective TLR7 agonist, AZD8848. BMJ Open Respir Res. 2016 Feb 23;3(1):e000113. doi: 10.1136/bmjresp-2015-000113. eCollection 2016.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	AZD8848	Small molecule	—	Inhaled

Indications

No indication recorded.