TRISILICATE

also known as Magnesium tri-silicate · Mag trisil co · Magnesium silicates magnesium trisilicate · Magnesium trisilicate component of foamcoat · Magnesium trisilicate component of foamicon · Magnesium trisilicate component of gaviscon · Magnesium trisilicate hydrate · Trimax

Small molecule

Developed for: gastroesophageal reflux disease
Investigated by: Universiti Sains Malaysia

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

Milestone	Jurisdiction	Brand	Indication	Date	Sentence it was read from
Approved	US (FDA)	GAVISCON	—	1983-12-09	fda.gov ↗

Trials 1 · a red edge is where a trial was stopped

today

US approved 1983

NCT03516188 · Ph 2/3

198319841985198619871988198919901991199219931994199519961997199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027

Phase	Registry id	Dates	Indication	Sponsor	Status	Outcome
Phase 2/3	NCT03516188	Jul 2016 → Jun 2017	gastroesophageal reflux disease, obesity disorder	Universiti Sains Malaysia	Completed	No outcome recorded

Also used as a comparator or background therapy in 1 trial

Phase	Registry id	Dates	Indication	Sponsor	Status	Outcome
Phase 4	NCT00343161 Background	Aug 2006 → Aug 2007	gastroesophageal reflux disease	AstraZeneca	Completed	No outcome recorded

Evidence & citations 10 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

Field	Value	Cited text
Known as	TRISILICATE	ChEMBL registry synonym — accepted as the source's own label CHEMBL2109882 ↗
Known as	Mag trisil co	ChEMBL registry synonym — accepted as the source's own label CHEMBL2109882 ↗
Known as	Magnesium silicates magnesium trisilicate	ChEMBL registry synonym — accepted as the source's own label CHEMBL2109882 ↗
Known as	Magnesium tri-silicate	“4 mL of magnesium tri-silicate which has equivalent strength and component with Gaviscon-Advance® except it is alginate-free” NCT03516188 ↗ 1 NCT00343161 ↗
Known as	Magnesium trisilicate component of foamcoat	ChEMBL registry synonym — accepted as the source's own label CHEMBL2109882 ↗
Known as	Magnesium trisilicate component of foamicon	ChEMBL registry synonym — accepted as the source's own label CHEMBL2109882 ↗
Known as	Magnesium trisilicate component of gaviscon	ChEMBL registry synonym — accepted as the source's own label CHEMBL2109882 ↗
Known as	Magnesium trisilicate hydrate	ChEMBL registry synonym — accepted as the source's own label CHEMBL2109882 ↗
Known as	Trimax	ChEMBL registry synonym — accepted as the source's own label CHEMBL2109882 ↗
Modality	Small molecule	— CHEMBL2109882 ↗