drugset / Trial / NCT00343161
Symptom Adapted Therapy in GERD Patients
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of the study is to determine whether a maintenance treatment over 12 weeks with esomeprazole 20 mg daily will sufficiently give control over GERD symptoms and how it compares either with an on-demand therapy with esomeprazole 20 mg or an as needed therapy (wait and see regimen) with rescue medication only (antacid), following a 4-weeks acute treatment phase with either esomeprazole 20 mg or esomeprazole 40 mg.
Timeline
- Start
- 2006-08
- Primary completion
- 2007-08
- Completion
- 2007-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Esomeprazole | Small molecule | 20 mg | — |
| Subject | Esomeprazole | Small molecule | 40 mg | — |
| Background | Aluminum hydroxide gel | Unknown | — | — |
| Background | TRISILICATE | Small molecule | — | — |