Drugs / LY2510924
last change Jul 2019 re-read 9 days ago

LY2510924

Peptide targets CXCR4 via inhibition

Developed for
cancer · clear cell renal carcinoma · leukemia · small cell lung carcinoma
Investigated by
Eli Lilly and Company · AstraZeneca · High Impact Clinical Research Support Program · M.D. Anderson Cancer Center

Trials 4

2012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT02737072 Sep 2016 → Sep 2017 cancer Eli Lilly and Company Terminated No outcome recorded
Phase 1 NCT02652871 May 2016 → Jul 2019 leukemia M.D. Anderson Cancer Center Completed No outcome recorded
Phase 22 trials · 2 missed
Phase 2 NCT01439568 Sep 2011 → Jan 2014 small cell lung carcinoma Eli Lilly and Company Completed Missed primary
Phase 2 NCT01391130 Aug 2011 → Sep 2014 clear cell renal carcinoma Eli Lilly and Company Terminated Missed primary

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as LY2510924 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01439568 ↗
3

NCT01391130 ↗

NCT02737072 ↗

NCT02652871 ↗

Action Inhibit “antagonist of CXCR4” PMID 27154357 ↗ Oct 2016
Modality Peptide “a peptide antagonist of CXCR4” PMID 27154357 ↗ Oct 2016
Route Subcutaneous “Administered subcutaneously” NCT01391130 ↗
Target CXCR4 “antagonist of CXCR4” PMID 27154357 ↗ Oct 2016