drugset / Trial / NCT02737072

A Study of LY2510924 and Durvalumab in Participants With Solid Tumors

NCT02737072

Phase 1 Terminated 9 enrolled Eli Lilly and Company AstraZeneca · collab
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The main purpose of this study is to evaluate the safety and tolerability of chemokine (C-X-C Motif) receptor 4 (CXCR4) peptide antagonist LY2510924 and durvalumab for phase 1a and 1b in participants with advanced refractory solid tumors.

Timeline

Start
2016-09
Primary completion
2017-09-25
Completion
2017-09-25

Drugs

EvaluationDrugModalityDoseRoute
Subject Durvalumab Monoclonal antibody 1500 mg Intravenous
Subject LY2510924 Peptide 20 mg Subcutaneous
Subject LY2510924 Peptide 30 mg Subcutaneous
Subject LY2510924 Peptide 40 mg Subcutaneous

Indications