Drugs / Cenerimod
last change Mar 2026 re-read 2 minutes ago

Cenerimod

also known as ACT-334441

Small molecule targets S1PR1

Developed for
systemic lupus erythematosus · lupus nephritis
Investigated by
Viatris Innovation GmbH · Viatris Pharmaceuticals Co., Ltd.

Trials 14 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 17 trials
Phase 1 NCT07301723 Dec 2025 → Mar 2026 Viatris Innovation GmbH Completed No outcome recorded
Phase 1 NCT05004311 Sep 2021 → Jul 2023 impaired renal function disease Viatris Innovation GmbH Completed No outcome recorded
Phase 1 NCT04819464 Aug 2021 → Aug 2024 Viatris Innovation GmbH Completed No outcome recorded
Phase 1 NCT04255277 Jan 2020 → Sep 2021 Viatris Innovation GmbH Completed No outcome recorded
Phase 1 NCT04052360 Aug → Oct 2019 Viatris Innovation GmbH Completed No outcome recorded
Phase 1 NCT02914223 Sep → Dec 2016 Viatris Innovation GmbH Completed No outcome recorded
Phase 1 NCT02479204 Apr 2015 → May 2016 Viatris Innovation GmbH Terminated No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT02472795 Jun 2015 → Jan 2017 systemic lupus erythematosus Viatris Innovation GmbH Completed No outcome recorded
Phase 22 trials
Phase 2 NCT07266090 Jan 2026 → Oct 2027 expected systemic lupus erythematosus Viatris Pharmaceuticals Co., Ltd. Active not recruiting No outcome recorded
Phase 2 NCT03742037 Dec 2018 → Aug 2021 systemic lupus erythematosus Viatris Innovation GmbH Completed No outcome recorded
Phase 34 trials
Phase 3 NCT07201129 Feb 2026 → Aug 2029 expected lupus nephritis, systemic lupus erythematosus Viatris Innovation GmbH Recruiting No outcome recorded
Phase 3 NCT06475742 Jul 2024 → May 2028 expected systemic lupus erythematosus Viatris Innovation GmbH Enrolling by invitation No outcome recorded
Phase 3 NCT05672576 Jun 2023 → Oct 2026 expected systemic lupus erythematosus Viatris Innovation GmbH Active not recruiting No outcome recorded
Phase 3 NCT05648500 Dec 2022 → Oct 2026 expected systemic lupus erythematosus Viatris Innovation GmbH Active not recruiting No outcome recorded

Press releases naming this drug 1 release

DateIssuerRelease
2024-12-18 Pfizer's Upjohn has merged with Mylan to form Viatris Inc. Viatris Announces Publication of Phase 2b CARE Study Data for Cenerimod in Lancet Rheumatology viatris.com

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 15 sources stand behind the page.

FieldValueCited text
Known as Cenerimod ClinicalTrials.gov intervention name — accepted as the source's own label NCT07301723
12

NCT05672576

NCT06475742

NCT02914223

NCT05648500

NCT03742037

NCT04819464

NCT02472795

NCT07201129

NCT05004311

NCT04255277

NCT04052360

NCT07266090

Known as ACT-334441 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02479204
Modality Small molecule CHEMBL4297505
Route Oral “Participants will receive cenerimod 0.5 mg capsules orally once daily for 12 weeks.” NCT02472795
Target S1PR1 “Sphingosine 1-phosphate receptor Edg-1 modulator” CHEMBL4297505