drugset / Trial / NCT04255277
To Study the Effect of Cenerimod on the Electrical Activity of the Heart, in Men and Women. To Study the Effect of Cenerimod on the Use of Oral Contraceptives in Women. To Study the Effect That Charcoal Has on the Elimination of Cenerimod From the Body, in Women and Men.
RandomizedParallel-groupQuadruple-blindOther
Summary
This is a single-center, randomized, double-blind for cenerimod, open-label for moxifloxacin, placebo- and moxifloxacin-controlled, parallel-group study to investigate the effect of cenerimod on the duration of the QT interval in healthy male and female participants. Participants will be randomly assigned to one of the 4 treatments: placebo, cenerimod 0.5 mg, cenerimod 4 mg or moxifloxacin.
Timeline
- Start
- 2020-01-31
- Primary completion
- 2021-09-14
- Completion
- 2021-10-18
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cenerimod | Small molecule | 0.5 mg | Oral |
| Subject | Cenerimod | Small molecule | 4 mg | Oral |
| Subject | Levonorgestrel | Small molecule | 0.1 mg | Oral |
| Subject | Moxifloxacin | Small molecule | 400 mg | Oral |
| Subject | ethinyl estradiol | Small molecule | 0.02 mg | Oral |
Indications
No indication recorded.