Drugs / Regulatory T cells

Trials 9 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT04691232 Feb 2021 → Apr 2023 autoimmune disease, ulcerative colitis University of Erlangen-Nürnberg Medical School Completed No outcome recorded
Phase 1 NCT01624077 Dec 2014 → Dec 2015 chronic transplant rejection Nanjing Medical University Unknown No outcome recorded
Phase 1 NCT01911039 Jul 2013 → Dec 2017 graft versus host disease Laura Johnston Completed No outcome recorded
Phase 1/25 trials
Phase 1/2 NCT03865017 Dec 2019 → Dec 2020 Alzheimer disease VTBIO Co. LTD Unknown No outcome recorded
Phase 1/2 NCT02704338 Apr 2016 → Mar 2018 autoimmune disease Nanjing Medical University Unknown No outcome recorded
Phase 1/2 NCT01163201 Jan 2014 → Jan 2015 Burkitt lymphoma, acute myeloid leukemia, blast phase chronic myelogenous leukemia, BCR-ABL1 positive, chronic lymphocytic leukemia/small lymphocytic lymphoma +8 Masonic Cancer Center, University of Minnesota Withdrawn No outcome recorded
Phase 1/2 NCT01660607 Feb 2012 → Dec 2023 acute lymphoblastic leukemia, acute myeloid leukemia, chronic myeloid leukemia, myelodysplastic syndrome Stanford University Completed No outcome recorded
Phase 1/2 NCT01050764 Jun 2009 → Aug 2012 B-cell chronic lymphocytic leukemia, acute myeloid leukemia, chronic myeloid leukemia, myelodysplastic syndrome Everett Meyer Terminated No outcome recorded
Phase 21 trial
Phase 2 NCT03977103 Feb 2014 → Feb 2023 acute lymphoblastic leukemia, acute myeloid leukemia, plasma cell myeloma University Of Perugia Unknown No outcome recorded

Press releases naming this drug 2 releases

DateIssuerRelease
2020-10-22 Daiichi Sankyo Daiichi Sankyo Initiates Phase 1 Trial with Immuno-Oncology Therapy DS-1055 Targeting GARP on Activated Regulatory T Cells daiichisankyo.com
2015-04-14 Pfizer REGiMMUNE Announces Collaboration with JDRF and Pfizer Inc. for Type 1 Diabetes Prevention and Treatment Promoting Regulatory T-Cells pfizer.com

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 10 sources stand behind the page.

FieldValueCited text
Known as Regulatory T cells “Patients received an infusion of 2 × 106/kg donor regulatory T cells on day -4 followed by 1 × 106/kg donor conventional T cells on day -1 and a mean of 10.7 × 106 ± 3.4 ×...” PMID 33646302 Mar 2021
7

NCT01624077

NCT01050764

NCT03865017

NCT01660607

NCT02704338

NCT01911039

NCT04691232

Known as Treg “Regulatory T-Cells (Treg)” NCT01660607
Known as Treg cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT01163201
Known as Tregs “The patient received a single infusion of 1×106 autologous, ex vivo expanded, polyclonal Tregs per kilogram of body weight, and the clinical, biochemical, endoscopic and...” PMID 35428657 Apr 2022
Modality Cell therapy “These are the enriched but naturally-occurring regulatory T cells.” NCT01050764
Route Other “Given by infusion on Day 0 after transplantation” NCT01163201