drugset / Trial / NCT01624077

Safety Study of Using Regulatory T Cells Induce Liver Transplantation Tolerance

NCT01624077

NaSingle-groupOpen-labelTreatment

Summary

The first trial will involve the generation of donor alloantigen-specific CD4+CD25+ Tregs from peripheral blood of pre-transplant patients, the administration of the CD4+CD25+ Tregs (1 x 106 cells/kg) at several intervals (for graft specific tolerance induction).

Timeline

Start
2014-12
Primary completion
2015-12
Completion
2015-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Regulatory T cells Cell therapy 1e+06 cells/kg