Drugs / streptozocin
streptozocin
also known as
streptozotocin · Estreptozocina · NSC-37917 · NSC-85998 · Streptozocine · U-9889 · Zanosar
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | ZANOSAR | — | 1982-05-07 | fda.gov ↗ |
Trials 8 · a red edge is where a trial was stopped
Also used as a comparator or background therapy in 3 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT00003543 Background | Jun 1998 → Aug 2002 | colorectal cancer | Memorial Sloan Kettering Cancer Center | Completed | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT00094497 Comparator | Jun 2004 → Dec 2010 | adrenal cortex carcinoma | Collaborative Group for Adrenocortical Carcinoma Treatment | Completed | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT07083232 Background | Oct 2024 | diabetes mellitus, myocardial infarction | Al-Azhar University | Completed | No outcome recorded |
Evidence & citations 10 cited values
Every value below carries the sentence it was read from. 13 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | streptozocin | “or streptozocin (streptozotocin) (1 g on days 1 to 5 in cycle 1; 2 g on day 1 in subsequent cycles) every 3 weeks” PMID 22551107 ↗ May 2012 |
| Known as | Estreptozocina | ChEMBL registry synonym — accepted as the source's own label CHEMBL1977579 ↗ |
| Known as | NSC-37917 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1977579 ↗ |
| Known as | NSC-85998 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1977579 ↗ |
| Known as | Streptozocine | ChEMBL registry synonym — accepted as the source's own label CHEMBL1977579 ↗ |
| Known as | streptozotocin | “Randomized Open Label Study to Compare the Efficacy and Safety of Everolimus Followed by Chemotherapy With Streptozotocin- Fluorouracilo (STZ-5FU) Upon Progression or the...” NCT02246127 ↗ |
| Known as | U-9889 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1977579 ↗ |
| Known as | Zanosar | ChEMBL registry synonym — accepted as the source's own label CHEMBL1977579 ↗ |
| Modality | Small molecule | — CHEMBL1977579 ↗ |
| Route | Intravenous | “streptozocin IV every 7 days, beginning on day 29, for 10 doses” NCT00003543 ↗ |