Drugs / streptozocin

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved US (FDA) ZANOSAR — 1982-05-07 fda.gov ↗

Trials 8

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 27 trials
Phase 2 NCT03351296 Jun 2018 → Dec 2028 expected malignant pancreatic neoplasm Gustave Roussy, Cancer Campus, Grand Paris Active not recruiting No outcome recorded
Phase 2 NCT02788201 Mar 2017 → Oct 2019 urinary bladder cancer, urothelial carcinoma National Cancer Institute (NCI) Completed No outcome recorded
Phase 2 NCT00609765 Aug 2007 → Mar 2008 malignant pancreatic neoplasm H. Lee Moffitt Cancer Center and Research Institute Terminated No outcome recorded
Phase 2 NCT00448136 Jul 2007 → Nov 2011 neoplasm Hoffmann-La Roche Completed No outcome recorded
Phase 2 NCT00602082 Aug 2005 → Dec 2009 carcinoid tumor, pancreatic neuroendocrine tumor Cambridge University Hospitals NHS Foundation Trust Completed No outcome recorded
Phase 2 NCT00004688 Aug 1996 → Jul 1998 anaplastic astrocytoma, anaplastic oligodendroglioma, glioblastoma, mixed glioma +1 Emory University Completed No outcome recorded
Phase 2 NCT00001165 Sep 1978 → Aug 2003 Zollinger-Ellison syndrome, adenoma of pancreas, metastatic neoplasm National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Completed No outcome recorded
Phase 31 trial · 1 missed
Phase 3 NCT02246127 Oct 2014 → Nov 2020 neuroendocrine neoplasm Spanish Group for Research in Neuroendocrine Tumors Completed Missed primary
Comparator or background therapy3 trials
Phase 1 NCT00003543 Background Jun 1998 → Aug 2002 colorectal cancer Memorial Sloan Kettering Cancer Center Completed No outcome recorded
Phase 3 NCT00094497 Comparator Jun 2004 → Dec 2010 adrenal cortex carcinoma Collaborative Group for Adrenocortical Carcinoma Treatment Completed No outcome recorded
Phase 4 NCT07083232 Background Oct 2024 diabetes mellitus, myocardial infarction Al-Azhar University Completed No outcome recorded

Evidence & citations 10 cited values

Every value below carries the sentence it was read from. 13 sources stand behind the page.

FieldValueCited text
Known as streptozocin “or streptozocin (streptozotocin) (1 g on days 1 to 5 in cycle 1; 2 g on day 1 in subsequent cycles) every 3 weeks” PMID 22551107 ↗ May 2012
6

“Sorafenib, Streptozocin, Sunitinib” NCT02788201 ↗

“Streptozocin” NCT03351296 ↗

NCT00609765 ↗

NCT00602082 ↗

NCT00003543 ↗

NCT00004688 ↗

Known as Estreptozocina ChEMBL registry synonym — accepted as the source's own label CHEMBL1977579 ↗
Known as NSC-37917 ChEMBL registry synonym — accepted as the source's own label CHEMBL1977579 ↗
Known as NSC-85998 ChEMBL registry synonym — accepted as the source's own label CHEMBL1977579 ↗
Known as Streptozocine ChEMBL registry synonym — accepted as the source's own label CHEMBL1977579 ↗
Known as streptozotocin “Randomized Open Label Study to Compare the Efficacy and Safety of Everolimus Followed by Chemotherapy With Streptozotocin- Fluorouracilo (STZ-5FU) Upon Progression or the...” NCT02246127 ↗
4

NCT00001165 ↗

NCT00094497 ↗

NCT07083232 ↗

NCT00448136 ↗

Known as U-9889 ChEMBL registry synonym — accepted as the source's own label CHEMBL1977579 ↗
Known as Zanosar ChEMBL registry synonym — accepted as the source's own label CHEMBL1977579 ↗
Modality Small molecule — CHEMBL1977579 ↗
Route Intravenous “streptozocin IV every 7 days, beginning on day 29, for 10 doses” NCT00003543 ↗