drugset / Trial / NCT07083232
The Effect of Sitagliptin, Pioglitazone and Dapagliflozine on Myocardial Infarction in Diabetic Rats
RandomizedParallel-groupOpen-labelPrevention
Summary
The aim of the present study is to evaluate the prophylactic effect of Sitagliptin, Pioglitazone and Dapagliflozine on Isoprenaline induced myocardial infarction in type II diabetic rats.
Timeline
- Start
- 2024-10-30
- Primary completion
- 2024-10-30
- Completion
- 2024-11-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dapagliflozin | Small molecule | 1 mg/kg | Oral |
| Subject | Pioglitazone | Small molecule | 10 mg/kg | Oral |
| Subject | Sitagliptin | Small molecule | 10 mg/kg | Oral |
| Background | streptozocin | Small molecule | 40 mg/kg | Other |