Dapagliflozin
Small molecule targets OTUD1, SLC5A2 via inhibition
Regulatory milestones approvals, filings & regulatory actions · 10 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Label expansions (8) | US (FDA) | FARXIGA | — | 2015-03-11 – 2024-06-12 | fda.gov ↗ |
| Approved | US (FDA) | FARXIGA | — | 2014-01-08 | fda.gov ↗ |
| Approved | EU (EMA) | Forxiga | — | 2012-11-11 | europa.eu ↗ |
Trials 426 · started per year
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 04 trials | ||||||
| Phase 0 | NCT07235280 | Dec 2025 → Jun 2028 expected | lung adenocarcinoma | Jonsson Comprehensive Cancer Center | Recruiting | No outcome recorded |
| Phase 0 | NCT06373523 | Sep 2024 → Jun 2025 overdue | NAFLD1, fibrotic liver disease | Post Graduate Institute of Medical Education and Research, Chandigarh | Not yet recruiting | No outcome recorded |
| Phase 0 | NCT06812429 | May 2024 → Apr 2025 | — | Washington University School of Medicine | Completed | No outcome recorded |
| Phase 0 | NCT05262257 | Apr 2022 → Dec 2023 | type 2 diabetes mellitus | The First Affiliated Hospital with Nanjing Medical University | Unknown | No outcome recorded |
| Phase 163 trials | ||||||
| Phase 1 | NCT07396844 | Jul 2026 overdue | — | LG Chem | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT07590466 | May → Jul 2026 overdue | hypertensive disorder, type 2 diabetes mellitus | Autotelicbio | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT07404137 | Feb → Apr 2026 | — | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT07399470 | Jan → Feb 2026 overdue | — | LG Chem | Active not recruiting | No outcome recorded |
| Phase 1 | NCT07333742 | Sep → Nov 2025 | — | LG Chem | Completed | No outcome recorded |
| Phase 1 | NCT07044765 | Aug → Nov 2025 overdue | type 2 diabetes mellitus | AJU Pharm Co., Ltd. | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT07034781 | Aug → Nov 2025 overdue | type 2 diabetes mellitus | AJU Pharm Co., Ltd. | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT07083401 | Jul 2025 → Jul 2026 overdue | diabetes mellitus | Boryung Pharmaceutical Co., Ltd | Recruiting | No outcome recorded |
| Phase 1 | NCT07083388 | Jul 2025 → Jul 2026 overdue | diabetes mellitus | Boryung Pharmaceutical Co., Ltd | Recruiting | No outcome recorded |
| Phase 1 | NCT06979388 | May → Jul 2025 | — | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT06831864 | Feb → May 2025 | symptomatic heart failure | Washington University School of Medicine | Completed | No outcome recorded |
| Phase 1 | NCT06612086 | Oct 2024 → Sep 2025 overdue | pulmonary hypertension | Assiut University | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT06651021 | Oct 2024 | — | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT05989347 | Oct 2024 → Dec 2027 expected | Her2-receptor negative breast cancer, hyperinsulinism | Yale University | Recruiting | No outcome recorded |
| Phase 1 | NCT06233045 | Jul → Aug 2024 | — | Bio-innova Co., Ltd | Unknown | No outcome recorded |
| Phase 1 | NCT04887935 | Jun 2024 → Nov 2025 | prostate carcinoma | Washington University School of Medicine | Terminated | No outcome recorded |
| Phase 1 | NCT06063109 | Oct → Nov 2023 | hypertensive disorder, type 2 diabetes mellitus | THPharm Corp. | Completed | No outcome recorded |
| Phase 1 | NCT05762952 | Jun 2023 → Aug 2025 overdue | myocardial ischemia | University of Virginia | Recruiting | No outcome recorded |
| Phase 1 | NCT05521984 | Apr 2023 → Mar 2031 expected | brain cancer, childhood malignant neoplasm | Washington University School of Medicine | Recruiting | No outcome recorded |
| Phase 1 | NCT05453786 | Jun → Aug 2022 | — | SK Chemicals Co., Ltd. | Completed | No outcome recorded |
| Phase 1 | NCT05429593 | Jun 2022 → Mar 2023 | — | Novo Nordisk A/S | Completed | No outcome recorded |
| Phase 1 | NCT04234867 | May → Aug 2022 | diabetic ketoacidosis, type 1 diabetes mellitus | Kinderkrankenhaus auf der Bult | Terminated | No outcome recorded |
| Phase 1 | NCT06165965 | May → Jun 2022 | — | Jeil Pharmaceutical Co., Ltd. | Completed | No outcome recorded |
| Phase 1 | NCT05411965 | Apr → Jul 2022 | type 2 diabetes mellitus | Boryung Pharmaceutical Co., Ltd | Completed | No outcome recorded |
| Phase 1 | NCT05105698 | Jan → Feb 2022 | — | LG Chem | Unknown | No outcome recorded |
| Phase 1 | NCT05403281 | Nov → Dec 2021 | — | Dong Wha Pharmaceutical Co. Ltd. | Completed | No outcome recorded |
| Phase 1 | NCT05236998 | Nov → Dec 2021 | — | SK Chemicals Co., Ltd. | Completed | No outcome recorded |
| Phase 1 | NCT04991571 | Jul → Oct 2021 | chronic kidney disease | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT04798222 | Jun → Sep 2021 | heart failure | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT04542291 | Feb → Dec 2021 | malignant pancreatic neoplasm | Washington University School of Medicine | Completed | No outcome recorded |
| Phase 1 | NCT04544319 | Oct 2020 → Mar 2021 | type 2 diabetes mellitus | LG Chem | Unknown | No outcome recorded |
| Phase 1 | NCT04972539 | Aug → Nov 2020 | type 2 diabetes mellitus | AJU Pharm Co., Ltd. | Completed | No outcome recorded |
| Phase 1 | NCT05066516 | Jun → Aug 2020 | diabetes mellitus | Korea University Anam Hospital | Completed | No outcome recorded |
| Phase 1 | NCT04084184 | Mar 2019 | — | Hanmi Pharmaceutical Company Limited | Completed | No outcome recorded |
| Phase 1 | NCT03826641 | Feb → Mar 2019 | — | Hanmi Pharmaceutical Company Limited | Completed | No outcome recorded |
| Phase 1 | NCT03766724 | Nov 2018 → Jan 2019 | type 2 diabetes mellitus | Dong-A ST Co., Ltd. | Completed | No outcome recorded |
| Phase 1 | NCT03704818 | Oct 2018 → Jun 2021 | type 1 diabetes mellitus | University of California, San Diego | Completed | No outcome recorded |
| Phase 1 | NCT03616392 | Jul → Sep 2018 | type 2 diabetes mellitus | Chong Kun Dang Pharmaceutical | Completed | No outcome recorded |
| Phase 1 | NCT03601910 | Jul → Sep 2018 | type 2 diabetes mellitus | Chong Kun Dang Pharmaceutical | Unknown | No outcome recorded |
| Phase 1 | NCT03565458 | Apr → Aug 2018 | type 2 diabetes mellitus | LG Chem | Unknown | No outcome recorded |
| Phase 1 | NCT03364985 | Dec 2017 → May 2019 | — | Daewoong Pharmaceutical Co. LTD. | Completed | No outcome recorded |
| Phase 1 | NCT03169959 | May → Aug 2017 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT02987738 | Feb → Dec 2017 | type 1 diabetes mellitus | Kinderkrankenhaus auf der Bult | Completed | No outcome recorded |
| Phase 1 | NCT02696941 | Feb 2016 → Apr 2018 | NAFLD1 | University of Oxford | Completed | No outcome recorded |
| Phase 1 | NCT02582840 | Oct 2015 → Jun 2016 | type 1 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT02325206 | Dec 2014 → Dec 2015 | type 1 diabetes mellitus | Kinderkrankenhaus auf der Bult | Completed | No outcome recorded |
| Phase 1 | NCT01877889 | Jul 2013 → Mar 2014 | — | Janssen-Cilag International NV | Completed | No outcome recorded |
| Phase 1 | NCT01535677 | Apr → Jul 2013 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT01662999 | Aug → Nov 2012 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT01525238 | Jul 2012 → Sep 2014 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT01156246 | Jun → Aug 2010 | — | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT01135446 | May → Jun 2010 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT01068756 | Mar → Apr 2010 | type 2 diabetes mellitus | AstraZeneca | Terminated | No outcome recorded |
| Phase 1 | NCT01072578 | Feb → Apr 2010 | — | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT01055652 | Jan → Apr 2010 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT01055691 | Jan → Apr 2010 | — | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT01002807 | Nov → Dec 2009 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT00908271 | Jul → Aug 2009 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT00562250 | May → Aug 2008 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT00546741 | Nov 2007 → Feb 2008 | — | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT00538174 | Nov 2007 → May 2008 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT00688493 | Jul 2007 → Apr 2008 | — | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT00554450 | Mar 2006 → Oct 2008 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 1/25 trials | ||||||
| Phase 1/2 | NCT07678203 | May 2026 → Jan 2027 expected | chronic kidney disease, lupus nephritis, systemic lupus erythematosus | Hospital Civil Juan I. Menchaca | Active not recruiting | No outcome recorded |
| Phase 1/2 | NCT05719714 | Jan 2024 → Sep 2026 expected | chronic kidney disease, diastolic heart failure | Northwestern University | Recruiting | No outcome recorded |
| Phase 1/2 | NCT06113900 | Dec 2023 → Dec 2024 | lupus nephritis | Ain Shams University | Unknown | No outcome recorded |
| Phase 1/2 | NCT04401904 | Jun 2020 → Sep 2022 | — | The University of Texas Health Science Center at San Antonio | Completed | No outcome recorded |
| Phase 1/2 | NCT03801642 | Jan 2019 → Jul 2022 | Alzheimer disease | Jeff Burns, MD | Completed | No outcome recorded |
| Phase 265 trials | ||||||
| Phase 2 | NCT07682350 | Sep 2026 → Sep 2029 expected | diabetes mellitus | Odense University Hospital | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT07516847 | Sep 2026 → Jan 2029 expected | anemia, myelodysplastic syndrome | Seug yun Yoon, MD | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT07310433 | Jun 2026 → Oct 2029 expected | metastatic prostate carcinoma | Yung NA | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT07273838 | Mar 2026 → Aug 2028 expected | acute kidney injury, heart failure | Yale University | Recruiting | No outcome recorded |
| Phase 2 | NCT06072326 | Jan 2026 → Dec 2027 expected | diabetic kidney disease | University Medical Center Groningen | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT07222917 | Dec 2025 → May 2027 expected | chronic kidney disease | AstraZeneca | Recruiting | No outcome recorded |
| Phase 2 | NCT07174687 | Dec 2025 → Dec 2027 expected | diffuse secondary choroid atrophy, retinal degeneration | Washington University School of Medicine | Recruiting | No outcome recorded |
| Phase 2 | NCT06762964 | May 2025 → Feb 2027 expected | congenital cardiovascular shunt, diastolic heart failure, univentricular cardiopathy | Mayo Clinic | Recruiting | No outcome recorded |
| Phase 2 | NCT07018622 | May 2025 → Sep 2026 expected | cancer, cisplatin toxicity | National Institute of Medical Sciences and Nutrition Salvador Zubiran | Recruiting | No outcome recorded |
| Phase 2 | NCT06929169 | May 2025 → Jul 2026 overdue | end stage renal failure | Maximo Agustin Schiavone | Recruiting | No outcome recorded |
| Phase 2 | NCT06626737 | Apr → Dec 2025 overdue | acute graft versus host disease | The First Affiliated Hospital of Soochow University | Recruiting | No outcome recorded |
| Phase 2 | NCT06919523 | Apr → Aug 2025 overdue | — | Mansoura University | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT06897605 | Apr → Oct 2025 overdue | anemia due to chronic disorder, chronic kidney disease | Mansoura University | Recruiting | No outcome recorded |
| Phase 2 | NCT06887062 | Mar 2025 → Jul 2027 expected | Takayasu arteritis, temporal arteritis | University of Edinburgh | Recruiting | No outcome recorded |
| Phase 2 | NCT06845163 | Feb 2025 → Mar 2026 overdue | diabetic macular edema | Alexandria University | Recruiting | No outcome recorded |
| Phase 2 | NCT07245069 | Feb 2025 → Nov 2028 expected | breast cancer, chemotherapy-induced toxicity, heart failure | University Medical Centre Ljubljana | Recruiting | No outcome recorded |
| Phase 2 | NCT06748105 | Dec 2024 → Dec 2025 overdue | hyperglycemia | Lauro Fabián Amador Medina | Active not recruiting | No outcome recorded |
| Phase 2 | NCT06528405 | Nov 2024 → Jul 2027 expected | acute kidney injury | National Taiwan University Hospital | Recruiting | No outcome recorded |
| Phase 2 | NCT07555106 | Sep 2024 → Sep 2026 expected | — | University of Guadalajara | Active not recruiting | No outcome recorded |
| Phase 2 | NCT05833958 | Sep 2024 → Sep 2025 | type 2 diabetes mellitus | George Medicines PTY Limited | Withdrawn | No outcome recorded |
| Phase 2 | NCT06420167 | Jul 2024 → Apr 2027 expected | AL amyloidosis | Barbara Ann Karmanos Cancer Institute | Recruiting | No outcome recorded |
| Phase 2 | NCT06111768 | May 2024 → May 2026 overdue | cardio-renal syndrome | Yale University | Active not recruiting | No outcome recorded |
| Phase 2 | NCT06350123 | May 2024 → May 2025 | chronic kidney disease | AstraZeneca | Completed | No outcome recorded |
| Phase 2 | NCT06269484 | Feb → Dec 2024 | cirrhosis of liver | AstraZeneca | Completed | No outcome recorded |
| Phase 2 | NCT05914857 | Dec 2023 → Jun 2025 | glucose intolerance, prediabetes syndrome | Yangjin | Unknown | No outcome recorded |
| Phase 2 | NCT04640493 | Dec 2023 → Aug 2025 | heart failure, sleep apnea syndrome | Columbia University | Withdrawn | No outcome recorded |
| Phase 2 | NCT05938712 | Oct 2023 → Oct 2027 expected | disease related to solid organ transplantation | University Health Network, Toronto | Recruiting | No outcome recorded |
| Phase 2 | NCT06341842 | Oct 2023 → Apr 2025 | breast cancer | Fondazione IRCCS Policlinico San Matteo di Pavia | Unknown | No outcome recorded |
| Phase 2 | NCT05058859 | Sep 2023 → Oct 2024 | cystinuria | University of California, San Francisco | Withdrawn | No outcome recorded |
| Phase 2 | NCT05710367 | Aug 2023 → Aug 2024 | Fabry disease | Albina Nowak, MD | Unknown | No outcome recorded |
| Phase 2 | NCT05884866 | Jul 2023 → Dec 2025 | chronic renal failure syndrome, disorder of acid-base balance | Klinikum Nürnberg | Completed | No outcome recorded |
| Phase 2 | NCT06155604 | Jan 2023 → Dec 2026 expected | chronic kidney disease, lupus nephritis | The University of Hong Kong | Recruiting | No outcome recorded |
| Phase 2 | NCT05516498 | Oct 2022 → May 2025 | cirrhosis of liver | AstraZeneca | Terminated | No outcome recorded |
| Phase 2 | NCT04930549 | Oct 2022 → Sep 2024 | chronic kidney disease | University Hospital, Rouen | Completed | No outcome recorded |
| Phase 2 | NCT05570305 | Oct 2022 → Mar 2025 | chronic kidney disease | University Medical Center Groningen | Completed | No outcome recorded |
| Phase 2 | NCT05179668 | Oct 2022 → Jul 2025 | chronic kidney disease, heart disorder, kidney failure, type 2 diabetes mellitus | Medical University of Vienna | Completed | No outcome recorded |
| Phase 2 | NCT04782245 | Sep 2022 → Apr 2024 | advanced heart failure | Hospices Civils de Lyon | Withdrawn | No outcome recorded |
| Phase 2 | NCT05254626 | Aug 2022 → Jan 2024 | metabolic dysfunction-associated steatohepatitis | Cairo University | Completed | No outcome recorded |
| Phase 2 | NCT05420285 | Jun 2022 → Sep 2023 | heart failure | Assistance Publique - Hôpitaux de Paris | Unknown | No outcome recorded |
| Phase 2 | NCT05330013 | Jun 2022 | heart failure, myocardial disorder | National Heart, Lung, and Blood Institute (NHLBI) | Withdrawn | No outcome recorded |
| Phase 2 | NCT05359263 | Jun 2022 → Feb 2025 overdue | chronic kidney disease | Tor Biering-Sørensen | Recruiting | No outcome recorded |
| Phase 2 | NCT04899349 | Apr 2022 → May 2023 | breast cancer | Novartis Pharmaceuticals | Terminated | No outcome recorded |
| Phase 2 | NCT05250752 | Nov 2021 → Feb 2022 | end stage renal failure | Holbaek Sygehus | Unknown | No outcome recorded |
| Phase 2 | NCT04794517 | Nov 2021 → May 2024 | chronic kidney disease | Mario Negri Institute for Pharmacological Research | Completed | No outcome recorded |
| Phase 2 | NCT04818034 | Aug → Dec 2021 | cystinuria | University of California, San Francisco | Completed | No outcome recorded |
| Phase 2 | NCT05025735 | Aug 2021 → Dec 2022 | Her2-receptor negative breast cancer | Saint Luke's Health System | Unknown | No outcome recorded |
| Phase 2 | NCT04724837 | Apr 2021 → Jun 2023 | chronic kidney disease | AstraZeneca | Completed | No outcome recorded |
| Phase 2 | NCT04730947 | Feb 2021 → Nov 2022 | diastolic heart failure | Mayo Clinic | Completed | No outcome recorded |
| Phase 2 | NCT04595370 | Jan 2021 → Sep 2023 | chronic kidney disease, heart failure | AstraZeneca | Completed | No outcome recorded |
| Phase 2 | NCT04304560 | Mar 2020 → Mar 2021 | cardiomyopathy, systolic heart failure, type 2 diabetes mellitus | Damanhour University | Unknown | No outcome recorded |
| Phase 2 | NCT04258371 | Feb 2020 → Dec 2023 | — | University Health Network, Toronto | Unknown | No outcome recorded |
| Phase 2 | NCT04419337 | Sep 2019 → Jul 2023 | diabetes mellitus, stroke disorder | Chang Gung Memorial Hospital | Unknown | No outcome recorded |
| Phase 2 | NCT03190694 | Nov 2017 → Nov 2019 | chronic kidney disease, proteinuria | Hiddo Lambers Heerspink | Completed | No outcome recorded |
| Phase 2 | NCT03316131 | Oct 2017 → Jul 2018 | — | AstraZeneca | Completed | No outcome recorded |
| Phase 2 | NCT03180489 | May 2017 → Dec 2018 | — | Christopher Bell | Completed | No outcome recorded |
| Phase 2 | NCT02695810 | Feb 2016 → Sep 2018 | obesity disorder, prediabetes syndrome | Steno Diabetes Center Copenhagen | Completed | No outcome recorded |
| Phase 2 | NCT02520518 | Aug 2015 → May 2017 | — | Christopher Bell | Terminated | No outcome recorded |
| Phase 2 | NCT02371187 | Jun 2015 → Jan 2018 | — | Christopher Bell | Completed | No outcome recorded |
| Phase 2 | NCT02279407 | Jan → Dec 2015 | NAFLD1 | AstraZeneca | Completed | No outcome recorded |
| Phase 2 | NCT02313220 | Dec 2014 → Mar 2016 | obesity disorder | Uppsala University | Completed | No outcome recorded |
| Phase 2 | NCT01498185 | Feb → Oct 2012 | type 1 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 2 | NCT00976495 | Oct 2009 → Nov 2010 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 2 | NCT00972244 | Aug 2009 → May 2010 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 2 | NCT00831779 | Apr 2009 → Aug 2010 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 2 | NCT00263276 | Dec 2005 → Feb 2007 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 2/318 trials | ||||||
| Phase 2/3 | NCT07684326 | Jul 2026 → Jul 2027 expected | — | Beni-Suef University | Recruiting | No outcome recorded |
| Phase 2/3 | NCT07214818 | Nov 2025 → Jul 2026 overdue | nephrotic syndrome | Mansoura University | Recruiting | No outcome recorded |
| Phase 2/3 | NCT07033585 | Jun 2025 → Oct 2026 expected | type 2 diabetes mellitus | Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator, IRB Chair | Active not recruiting | No outcome recorded |
| Phase 2/3 | NCT06783166 | Aug 2024 → Jul 2025 overdue | heart failure | Mansoura University | Recruiting | No outcome recorded |
| Phase 2/3 | NCT06111443 | Dec 2023 → Nov 2026 expected | atrial fibrillation | Chang Gung Memorial Hospital | Active not recruiting | No outcome recorded |
| Phase 2/3 | NCT05713851 | Jan 2023 → Dec 2024 | acute kidney injury, chronic kidney disease | National Institute of Medical Sciences and Nutrition Salvador Zubiran | Unknown | No outcome recorded |
| Phase 2/3 | NCT05676684 | Sep 2022 → Nov 2024 | diastolic heart failure | University of Porto | Completed | No outcome recorded |
| Phase 2/3 | NCT05406505 | Apr 2022 → May 2023 | heart failure | Mansoura University | Completed | No outcome recorded |
| Phase 2/3 | NCT06286878 | Dec 2021 → Jul 2025 overdue | acute coronary syndrome, cardiac ventricle disorder, diabetes mellitus, myocardial infarction | University of Sao Paulo | Recruiting | No outcome recorded |
| Phase 2/3 | NCT04764097 | Jun 2021 → Jun 2025 | cardiovascular disorder, end stage renal failure | Tan Tock Seng Hospital | Withdrawn | No outcome recorded |
| Phase 2/3 | NCT05565976 | Aug 2020 → Dec 2024 | cognitive impairment with or without cerebellar ataxia, ischemic stroke, metabolic syndrome X, vascular dementia | Jaime Daniel Mondragon | Unknown | No outcome recorded |
| Phase 2/3 | NCT04393246 | Jul 2020 → Jun 2022 | COVID-19 | Cambridge University Hospitals NHS Foundation Trust | Completed | No outcome recorded |
| Phase 2/3 | NCT04400760 | May 2020 → Jun 2022 | platelet disorder, undefined | The University of The West Indies | Completed | No outcome recorded |
| Phase 2/3 | NCT03899402 | May 2019 → Jan 2026 overdue | type 1 diabetes mellitus | State University of New York at Buffalo | Active not recruiting | No outcome recorded |
| Phase 2/3 | NCT03968224 | Aug 2018 → Jul 2024 | morbid obesity, prediabetes syndrome, type 2 diabetes mellitus | Centro Medico Nacional Siglo XXI IMSS | Completed | No outcome recorded |
| Phase 2/3 | NCT02547935 | Sep 2015 → May 2018 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 2/3 | NCT02113241 | Apr 2014 → May 2015 | metabolic syndrome X | University of Guadalajara | Completed | No outcome recorded |
| Phase 2/3 | NCT00357370 | Oct 2006 → Mar 2008 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3104 trials | ||||||
| Phase 3 | NCT06907251 | Sep 2026 → Jun 2028 expected | COVID-19, long COVID-19 | Ottawa Heart Institute Research Corporation | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07662109 | Jul 2026 → Jul 2028 expected | type 2 diabetes mellitus | AstraZeneca | Recruiting | No outcome recorded |
| Phase 3 | NCT07662044 | Jul 2026 → Jul 2028 expected | type 2 diabetes mellitus | AstraZeneca | Recruiting | No outcome recorded |
| Phase 3 | NCT07056699 | Jul 2026 → Jun 2027 expected | type 1 diabetes mellitus | The University of Texas Health Science Center at San Antonio | Recruiting | No outcome recorded |
| Phase 3 | NCT07488689 | Jul 2026 → Aug 2029 expected | infectious disease with sepsis | University Hospital, Strasbourg, France | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07569640 | Jun 2026 → Dec 2028 expected | symptomatic heart failure | Washington University School of Medicine | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07598864 | May 2026 → May 2027 expected | diabetic kidney disease | Chittagong Medical College | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT06405178 | Mar 2026 | polycystic ovary syndrome | Beni-Suef University | Completed | No outcome recorded |
| Phase 3 | NCT07297589 | Dec 2025 → Jan 2027 expected | ST-elevation myocardial infarction | Mexican Social Security Institute | Recruiting | No outcome recorded |
| Phase 3 | NCT07295223 | Dec 2025 → Aug 2026 overdue | ST-elevation myocardial infarction | Mexican Social Security Institute | Recruiting | No outcome recorded |
| Phase 3 | NCT07280585 | Dec 2025 → May 2030 expected | autosomal dominant polycystic kidney disease | University of Cologne | Recruiting | No outcome recorded |
| Phase 3 | NCT06750458 | Aug 2025 → Oct 2026 expected | glioma | Tanta University | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07105917 | Aug 2025 → Aug 2026 overdue | ischemic stroke | Second Affiliated Hospital, School of Medicine, Zhejiang University | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07026968 | Jun 2025 → Oct 2026 expected | type 2 diabetes mellitus | CSPC Ouyi Pharmaceutical Co., Ltd. | Active not recruiting | No outcome recorded |
| Phase 3 | NCT07187570 | Jun 2025 → Dec 2027 expected | atrial fibrillation | Region Stockholm | Recruiting | No outcome recorded |
| Phase 3 | NCT06982079 | May 2025 → Jun 2026 overdue | end stage renal failure | Ain Shams University | Recruiting | No outcome recorded |
| Phase 3 | NCT06647745 | Apr 2025 → Jun 2026 overdue | hypertensive disorder, type 2 diabetes mellitus | THPharm Corp. | Recruiting | No outcome recorded |
| Phase 3 | NCT06890143 | Mar 2025 → Dec 2026 expected | inherited kidney disorder | Children's Hospital of Fudan University | Recruiting | No outcome recorded |
| Phase 3 | NCT07356388 | Jan 2025 → Oct 2027 expected | disease related to solid organ transplantation, proteinuria | kewen Chen,MD | Active not recruiting | No outcome recorded |
| Phase 3 | NCT06174753 | Jan 2025 → Jun 2027 expected | ST-elevation myocardial infarction | Ottawa Heart Institute Research Corporation | Recruiting | No outcome recorded |
| Phase 3 | NCT06759077 | Dec 2024 overdue | kidney disorder | Al-Azhar University | Active not recruiting | No outcome recorded |
| Phase 3 | NCT06434025 | May 2024 → May 2026 overdue | iron metabolism disease, systolic heart failure | Hospital de Clinicas de Porto Alegre | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT06772168 | Apr 2024 → Nov 2026 expected | hyperlipidemia, type 2 diabetes mellitus | CMG Pharmaceutical Co. Ltd | Recruiting | No outcome recorded |
| Phase 3 | NCT06304857 | Apr 2024 → Dec 2026 expected | breast cancer, heart failure | 4th Military Clinical Hospital with Polyclinic, Poland | Recruiting | No outcome recorded |
| Phase 3 | NCT06307652 | Apr 2024 → Jun 2027 expected | heart failure | AstraZeneca | Recruiting | No outcome recorded |
| Phase 3 | NCT05944016 | Mar 2024 → Sep 2026 expected | chronic renal failure syndrome | University Hospital Goettingen | Recruiting | No outcome recorded |
| Phase 3 | NCT06711185 | Jan 2024 → Jan 2026 overdue | breast cancer | University of Campinas, Brazil | Recruiting | No outcome recorded |
| Phase 3 | NCT05468203 | Nov 2023 → Jul 2025 | acute kidney injury | The George Institute | Terminated | No outcome recorded |
| Phase 3 | NCT06117137 | Nov 2023 → Jan 2025 | NAFLD1 | Sohag University | Completed | No outcome recorded |
| Phase 3 | NCT05764057 | Jun 2023 → Oct 2026 expected | ST-elevation myocardial infarction | Assistance Publique - Hôpitaux de Paris | Recruiting | No outcome recorded |
| Phase 3 | NCT05849766 | Apr 2023 → May 2024 | dilated cardiomyopathy | October 6 University | Completed | No outcome recorded |
| Phase 3 | NCT05345327 | Jan 2023 → Jun 2026 overdue | type 2 diabetes mellitus | The George Institute | Recruiting | No outcome recorded |
| Phase 3 | NCT05618223 | Dec 2022 → May 2023 | heart failure, mitral valve stenosis, rheumatic heart disease | Universitas Sebelas Maret | Unknown | No outcome recorded |
| Phase 3 | NCT05374291 | Nov 2022 → Jul 2027 expected | chronic kidney disease, heart failure, kidney failure | University Medical Center Groningen | Enrolling by invitation | No outcome recorded |
| Phase 3 | NCT06142474 | Oct 2022 → Oct 2030 expected | heart failure, ventilation pneumonitis | National Taiwan University Hospital | Recruiting | No outcome recorded |
| Phase 3 | NCT05505994 | Sep 2022 → Feb 2024 | type 2 diabetes mellitus | Daewoong Pharmaceutical Co. LTD. | Unknown | No outcome recorded |
| Phase 3 | NCT07344922 | Sep 2022 → Nov 2023 | anemia, calcinosis, chronic kidney disease | Mansoura University | Completed | No outcome recorded |
| Phase 3 | NCT05310916 | Jun 2022 → May 2023 | diabetic retinopathy | Nidae Alaa | Unknown | No outcome recorded |
| Phase 3 | NCT05196347 | May 2022 → Aug 2024 | chronic kidney disease | Kaohsiung Medical University | Completed | No outcome recorded |
| Phase 3 | NCT04965935 | Jul 2021 → Aug 2024 | disease related to solid organ transplantation, type 2 diabetes mellitus | University Health Network, Toronto | Completed | No outcome recorded |
| Phase 3 | NCT05998525 | Jun 2021 → Dec 2022 | intermediate coronary syndrome, myocardial infarction, type 2 diabetes mellitus | Hilda Elizabeth Macías Cervantes | Completed | No outcome recorded |
| Phase 3 | NCT06619600 | May 2021 → Mar 2025 overdue | ST-elevation myocardial infarction, diabetes mellitus, heart failure | Hospital Clinic of Barcelona | Active not recruiting | No outcome recorded |
| Phase 3 | NCT04860011 | Apr 2021 → Oct 2022 | heart failure | NHS Greater Glasgow and Clyde | Unknown | No outcome recorded |
| Phase 3 | NCT06329674 | Apr 2021 → Dec 2022 | type 2 diabetes mellitus | AJU Pharm Co., Ltd. | Completed | No outcome recorded |
| Phase 3 | NCT04707352 | Feb 2021 → Mar 2023 | heart failure | Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia | Completed | No outcome recorded |
| Phase 3 | NCT04564742 | Dec 2020 → Jul 2023 | acute myocardial infarction, heart failure | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT04333823 | Dec 2020 → May 2024 overdue | type 1 diabetes mellitus | The Hospital for Sick Children | Active not recruiting | No outcome recorded |
| Phase 3 | NCT04255238 | Jun 2020 → May 2022 | type 2 diabetes mellitus | LG Chem | Unknown | No outcome recorded |
| Phase 3 | NCT04356742 | May 2020 → Feb 2022 | type 2 diabetes mellitus | Dong-A ST Co., Ltd. | Completed | No outcome recorded |
| Phase 3 | NCT04298229 | Apr 2020 → May 2023 | heart failure, type 2 diabetes mellitus | Vanderbilt University Medical Center | Completed | No outcome recorded |
| Phase 3 | NCT05109949 | Mar 2020 → Jun 2022 | type 2 diabetes mellitus | Centro Universitario de Ciencias de la Salud, Mexico | Unknown | No outcome recorded |
| Phase 3 | NCT04213677 | Mar 2020 → Oct 2022 | polycystic ovary syndrome | Nanfang Hospital, Southern Medical University | Completed | No outcome recorded |
| Phase 3 | NCT04035031 | Jan → Nov 2020 | type 1 diabetes mellitus | Insel Gruppe AG, University Hospital Bern | Completed | No outcome recorded |
| Phase 3 | NCT04195243 | Dec 2019 → Jun 2020 | type 2 diabetes mellitus | Centro Universitario de Ciencias de la Salud, Mexico | Unknown | No outcome recorded |
| Phase 3 | NCT03877237 | Apr 2019 → Mar 2020 | systolic heart failure | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT03877224 | Apr 2019 → Jul 2020 | diastolic heart failure | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT03723252 | Mar 2019 → Mar 2024 | metabolic dysfunction-associated steatohepatitis | Nanfang Hospital, Southern Medical University | Completed | No outcome recorded |
| Phase 3 | NCT03658031 | Mar 2019 → Dec 2020 | myocardial infarction, prediabetes syndrome, type 2 diabetes mellitus | Hamad Medical Corporation | Unknown | No outcome recorded |
| Phase 3 | NCT03794518 | Mar 2019 → Sep 2021 | — | Hamad Medical Corporation | Unknown | No outcome recorded |
| Phase 3 | NCT03608358 | Feb 2019 → Aug 2020 | type 2 diabetes mellitus | AstraZeneca | Terminated | No outcome recorded |
| Phase 3 | NCT03762850 | Dec 2018 → Aug 2023 overdue | IgA glomerulonephritis | Travere Therapeutics, Inc. | Active not recruiting | No outcome recorded |
| Phase 3 | NCT03619213 | Aug 2018 → Mar 2022 | diastolic heart failure | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT03419624 | Feb 2018 → Apr 2019 | obesity disorder, type 2 diabetes mellitus | University Medical Center Hamburg-Eppendorf | Terminated | No outcome recorded |
| Phase 3 | NCT03313752 | Dec 2017 → Oct 2022 | coronary artery disorder, type 2 diabetes mellitus | Giaccari Andrea | Completed | No outcome recorded |
| Phase 3 | NCT03199053 | Oct 2017 → Feb 2023 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT03036124 | Feb 2017 → Jul 2019 | heart failure | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT03036150 | Feb 2017 → Jun 2020 | chronic kidney disease | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT02946632 | Dec 2016 → Dec 2019 | type 2 diabetes mellitus | Korea University Anam Hospital | Unknown | No outcome recorded |
| Phase 3 | NCT02725593 | Jun 2016 → Apr 2020 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT02635386 | Mar 2016 → Jul 2020 | obesity disorder, polycystic ovary syndrome | Woman's | Completed | No outcome recorded |
| Phase 3 | NCT02582814 | Oct 2015 → Jun 2017 | type 1 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT02532855 | Oct 2015 → Oct 2017 | type 2 diabetes mellitus | Merck Sharp & Dohme LLC | Completed | No outcome recorded |
| Phase 3 | NCT02551874 | Oct 2015 → May 2017 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT02419612 | Aug 2015 → Aug 2017 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT02460978 | Jul 2015 → Sep 2017 | type 1 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT02413398 | Jun 2015 → Nov 2017 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT02268214 | Nov 2014 → Jan 2017 | type 1 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT02284893 | Sep 2014 → Sep 2016 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT02229396 | Sep 2014 → Apr 2016 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT02096705 | Mar 2014 → Jan 2016 | diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT01730534 | Apr 2013 → Sep 2018 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT01646320 | Sep 2012 → Aug 2014 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT01606007 | Jul 2012 → Jan 2014 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT01257412 | Jan 2012 → Jun 2013 | type 2 diabetes mellitus | AstraZeneca | Suspended | No outcome recorded |
| Phase 3 | NCT01392677 | Oct 2011 → Jan 2013 | hyperglycemia, type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT01294436 | Feb 2011 → Sep 2012 | hyperglycemia, type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT01294423 | Feb 2011 → Mar 2012 | hyperglycemia, type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT01217892 | Nov 2010 → Aug 2011 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT01195662 | Oct 2010 → Feb 2013 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT01137474 | Jul 2010 → Feb 2013 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT01095666 | Jun 2010 → Mar 2013 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT01095653 | Jun 2010 → Mar 2012 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT01042977 | Mar 2010 → May 2011 | cardiovascular disorder, type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT01031680 | Feb 2010 → May 2011 | hypertensive disorder, type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT00859898 | Apr 2009 → May 2010 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT00855166 | Feb 2009 → Jun 2010 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT00736879 | Sep 2008 → Dec 2009 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT00683878 | Jul 2008 → Jan 2010 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT00643851 | Jun 2008 → Aug 2009 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT00680745 | Apr 2008 → Nov 2009 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT00673231 | Apr 2008 → May 2009 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT00660907 | Mar 2008 → Dec 2009 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT00528879 | Sep 2007 → Nov 2008 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT00528372 | Sep 2007 → Feb 2009 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 4136 trials | ||||||
| Phase 4 | NCT07342764 | Sep 2026 → Nov 2028 expected | — | Sultan Qaboos University | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07631156 | Jun 2026 → Jun 2029 expected | left ventricular failure, symptomatic heart failure | Kyungsub Song | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07572032 | May 2026 → May 2028 expected | cardiac valvular defect, coronary artery disorder, heart failure | Kyungsub Song | Recruiting | No outcome recorded |
| Phase 4 | NCT07405216 | Apr 2026 → May 2027 expected | chronic kidney disease, proteinuria | Centenario Hospital Miguel Hidalgo | Recruiting | No outcome recorded |
| Phase 4 | NCT07482943 | Apr 2026 → Apr 2028 expected | heart failure | The University of Hong Kong | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07513883 | Mar 2026 → Sep 2028 expected | heart failure | Ziekenhuis Oost-Limburg | Recruiting | No outcome recorded |
| Phase 4 | NCT07351643 | Feb → Oct 2026 expected | acute coronary syndrome | Shenyang Northern Hospital | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07614230 | Jan 2026 → Jun 2027 expected | atherosclerosis, coronary artery disorder, type 2 diabetes mellitus | Junjie Yang | Recruiting | No outcome recorded |
| Phase 4 | NCT07311551 | Dec 2025 → Dec 2026 expected | type 2 diabetes mellitus | Bhavya Bhavya, MD | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07108985 | Sep 2025 → Sep 2029 expected | hyperglycemia, type 2 diabetes mellitus | Yonsei University | Not yet recruiting | No outcome recorded |
| Show all 136 trials opens the full record — a long page | ||||||
| Phase not applicable31 trials | ||||||
| — | NCT07595289 | Aug → Dec 2026 expected | type 2 diabetes mellitus | The Third Xiangya Hospital of Central South University | Not yet recruiting | No outcome recorded |
| — | NCT07679828 | Jul 2026 → Dec 2029 expected | diabetes mellitus, hyperlipidemia, hypertensive disorder | China Medical University, China | Not yet recruiting | No outcome recorded |
| — | NCT07491042 | Apr → Sep 2026 expected | end stage renal failure | Oman Ministry of Health | Recruiting | No outcome recorded |
| — | NCT07392788 | Apr 2026 → Dec 2027 expected | symptomatic heart failure | Centre Hospitalier Universitaire de Besancon | Not yet recruiting | No outcome recorded |
| — | NCT07403955 | Feb 2026 → Dec 2027 expected | congestive heart failure | Qilu Hospital of Shandong University | Not yet recruiting | No outcome recorded |
| — | NCT07331727 | Jan → Sep 2026 expected | atrial fibrillation | Shanghai Chest Hospital | Not yet recruiting | No outcome recorded |
| — | NCT07272057 | Dec 2025 → Oct 2026 expected | lung cancer | Shanghai Chest Hospital | Not yet recruiting | No outcome recorded |
| — | NCT07204743 | Aug 2025 → Jun 2026 overdue | proteinuria | Al-Quds University | Active not recruiting | No outcome recorded |
| — | NCT06740786 | Dec 2024 → May 2026 overdue | atrial fibrillation | Xu Liu | Not yet recruiting | No outcome recorded |
| — | NCT06719661 | Dec 2024 → May 2025 | type 2 diabetes mellitus | University of Sulaimani | Completed | No outcome recorded |
| — | NCT06433479 | Jul 2024 → Jul 2025 | atrial fibrillation | Beijing Anzhen Hospital | Completed | No outcome recorded |
| — | NCT06915870 | Jul 2024 → Jan 2025 | diabetes mellitus, heart failure | Fatima Maqsood | Completed | No outcome recorded |
| — | NCT06187493 | Jan 2024 → Jan 2025 | diabetic kidney disease | Assiut University | Unknown | No outcome recorded |
| — | NCT06147518 | Dec 2023 → Dec 2024 | cirrhosis of liver | Institute of Liver and Biliary Sciences, India | Unknown | No outcome recorded |
| — | NCT06091475 | Dec 2023 → Aug 2026 overdue | dilated cardiomyopathy, heart failure | Imperial College London | Recruiting | No outcome recorded |
| — | NCT05965440 | Nov 2023 → Feb 2026 | chronic kidney disease | Hospices Civils de Lyon | Completed | No outcome recorded |
| — | NCT06344247 | Sep 2023 → Sep 2025 | chronic kidney disease, obesity disorder | RenJi Hospital | Unknown | No outcome recorded |
| — | NCT05849220 | May 2023 → Mar 2024 | cirrhosis of liver | Institute of Liver and Biliary Sciences, India | Unknown | No outcome recorded |
| — | NCT07338331 | Apr 2023 → Apr 2025 | NAFLD1, type 2 diabetes mellitus | Galala University | Completed | No outcome recorded |
| — | NCT05390307 | Apr 2023 → Jan 2024 | type 1 diabetes mellitus | Dasman Diabetes Institute | Completed | No outcome recorded |
| — | NCT06065280 | Nov 2022 → Dec 2024 | heart failure | Damanhour University | Completed | No outcome recorded |
| — | NCT05795400 | Jun 2022 → May 2025 | amyloidosis, diastolic heart failure, mild heart failure | National Medical Research Center for Cardiology, Ministry of Health of Russian Federation | Completed | No outcome recorded |
| — | NCT07539584 | Mar 2022 → Apr 2024 | metabolic dysfunction-associated steatotic liver disease, type 2 diabetes mellitus | Moscow Regional Research and Clinical Institute (MONIKI) | Completed | No outcome recorded |
| — | NCT05141552 | Jan → Jul 2022 | — | RenJi Hospital | Unknown | No outcome recorded |
| — | NCT04923295 | Jun → Jul 2021 | — | An-Najah National University | Completed | No outcome recorded |
| — | NCT04882358 | May 2021 → Aug 2022 | heart failure | Sequana Medical N.V. | Unknown | No outcome recorded |
| — | NCT04717986 | Jan 2021 → Jun 2022 | acute myocardial infarction, heart failure, intermediate coronary syndrome | Mexican Social Security Institute | Completed | No outcome recorded |
| — | NCT04591639 | Aug 2020 → Jul 2028 expected | cardiomyopathy, heart failure | University of Edinburgh | Recruiting | No outcome recorded |
| — | NCT03917758 | Oct 2018 → Jul 2020 | hypertensive disorder, type 2 diabetes mellitus | University of Turin, Italy | Unknown | No outcome recorded |
| — | NCT02420392 | Feb 2015 → Apr 2016 | type 2 diabetes mellitus | Seoul National University Hospital | Completed | No outcome recorded |
| — | NCT01439854 | Mar 2011 → Jun 2018 | — | The University of Texas Health Science Center at San Antonio | Completed | No outcome recorded |
Also used as a comparator or background therapy in 184 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 02 trials | ||||||
| Phase 0 | NCT04780438 Comparator | Sep 2021 → Sep 2023 | atrial fibrillation | G.Gennimatas General Hospital | Unknown | No outcome recorded |
| Phase 0 | NCT04806633 Comparator | Apr 2021 → Sep 2023 | acute kidney injury | G.Gennimatas General Hospital | Unknown | No outcome recorded |
| Phase 111 trials | ||||||
| Phase 1 | NCT06759909 Comparator | Jan 2025 → Dec 2026 expected | atrial fibrillation | Assiut University | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT06639087 Comparator | Sep 2024 → May 2025 | heart failure, impaired renal function disease | AstraZeneca | Terminated | No outcome recorded |
| Phase 1 | NCT05217654 Comparator | Feb 2022 → Feb 2023 | vascular insufficiency disorder | Medical University of Vienna | Unknown | No outcome recorded |
| Phase 1 | NCT04856969 Comparator | Mar → May 2021 | — | Autotelicbio | Completed | No outcome recorded |
| Phase 1 | NCT03216278 Comparator | Sep 2017 → May 2018 | — | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT01165268 Comparator | Aug → Dec 2010 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT00930865 Comparator | Jul → Sep 2009 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT00904176 Comparator | Jun → Aug 2009 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT00726505 Comparator | Jun → Aug 2009 | diabetes mellitus | AstraZeneca | Terminated | No outcome recorded |
| Phase 1 | NCT00842556 Comparator | Mar → May 2009 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 1 | NCT00839683 Comparator | Feb → Mar 2009 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 1/24 trials | ||||||
| Phase 1/2 | NCT07239011 Comparator | Nov 2025 → Nov 2026 expected | depressive disorder | Tanta University | Recruiting | No outcome recorded |
| Phase 1/2 | NCT07020377 Comparator | Jan 2024 → Dec 2025 overdue | NAFLD1, type 2 diabetes mellitus | Amira Bisher,PhD | Active not recruiting | No outcome recorded |
| Phase 1/2 | NCT05965934 Background | Jul 2023 → Dec 2024 | heart failure | Sequana Medical N.V. | Unknown | No outcome recorded |
| Phase 1/2 | NCT04545411 Comparator | Feb 2021 → Feb 2022 | type 1 diabetes mellitus | University of California, San Diego | Completed | No outcome recorded |
| Phase 225 trials | ||||||
| Phase 2 | NCT07539259 Comparator | Dec 2026 → Aug 2029 expected | aortic valve stenosis | University College, London | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT07610174 Background | Jun 2025 → Apr 2026 | cardiac valvular defect, heart failure | Kafrelsheikh University | Completed | No outcome recorded |
| Phase 2 | NCT06942910 Comparator | May 2025 → Jul 2026 overdue | chronic kidney disease | AstraZeneca | Recruiting | No outcome recorded |
| Phase 2 | NCT06427226 Comparator | Oct 2024 → Oct 2026 expected | breast cancer, doxorubicin induced cardiomyopathy | Tanta University | Recruiting | No outcome recorded |
| Phase 2 | NCT06888505 Comparator | Sep 2024 → Sep 2025 | cardiomyopathy due to anthracyclines, chemotherapy-induced toxicity | Hawler Medical University | Completed | No outcome recorded |
| Phase 2 | NCT06012266 Comparator | Aug 2024 → Aug 2025 | heart failure | Centre Hospitalier Universitaire Vaudois | Unknown | No outcome recorded |
| Phase 2 | NCT06150924 Background | Dec 2023 → Feb 2025 | chronic kidney disease | Mineralys Therapeutics Inc. | Completed | No outcome recorded |
| Phase 2 | NCT06147271 Comparator | Nov 2023 → Feb 2025 | heart failure, transplant rejection | Federal University of Ceará | Unknown | No outcome recorded |
| Phase 2 | NCT05792540 Comparator | Jun 2023 → Nov 2024 | depressive disorder | Tanta University | Completed | No outcome recorded |
| Phase 2 | NCT05179356 Comparator | Jan 2023 → Jan 2026 | chronic thromboembolic pulmonary hypertension, pulmonary arterial hypertension | Mads Ersbøll | Completed | No outcome recorded |
| Phase 2 | NCT05268926 Comparator | Feb 2022 → Feb 2023 | proteinuria | University Medical Center Groningen | Terminated | No outcome recorded |
| Phase 2 | NCT04956809 Comparator | Oct 2021 → Jun 2023 | symptomatic heart failure | University of Pennsylvania | Completed | No outcome recorded |
| Phase 2 | NCT05014594 Comparator | Sep 2021 → May 2022 | cirrhosis of liver | Post Graduate Institute of Medical Education and Research, Chandigarh | Unknown | No outcome recorded |
| Phase 2 | NCT04956263 Comparator | Jun 2021 → Feb 2022 | type 1 diabetes mellitus | Youngene Therapeutics Inc., Ltd. | Completed | No outcome recorded |
| Phase 2 | NCT04492722 Background | Oct 2020 → Sep 2022 | chronic kidney disease | AstraZeneca | Terminated | No outcome recorded |
| Phase 2 | NCT04451837 Comparator | Sep 2020 → Dec 2021 overdue | type 2 diabetes mellitus | Region Skane | Active not recruiting | No outcome recorded |
| Phase 2 | NCT04475042 Comparator | Jul 2020 → Nov 2021 | diastolic heart failure | Mariëlle Scheffer | Unknown | No outcome recorded |
| Phase 2 | NCT04170543 Background | Nov 2019 → May 2023 | diabetic kidney disease | AstraZeneca | Completed | No outcome recorded |
| Phase 2 | NCT07515391 Comparator | Oct 2019 → May 2021 overdue | type 2 diabetes mellitus | Dasman Diabetes Institute | Enrolling by invitation | No outcome recorded |
| Phase 2 | NCT03556033 Comparator | Nov 2018 → Dec 2019 | hypoglycemia, type 1 diabetes mellitus | Radboud University Medical Center | Completed | No outcome recorded |
| Phase 2 | NCT03714594 Comparator | Jul 2018 → Aug 2022 | type 2 diabetes mellitus | University of Pisa | Completed | No outcome recorded |
| Phase 2 | NCT03537131 Comparator | Jun 2018 → Jul 2021 | type 1 diabetes mellitus | University of Oxford | Terminated | No outcome recorded |
| Phase 2 | NCT03444584 Background | May → Dec 2018 | type 2 diabetes mellitus | MedImmune LLC | Completed | No outcome recorded |
| Phase 2 | NCT02558270 Comparator | Jun 2016 → Dec 2017 | type 2 diabetes mellitus | Medical University of Vienna | Unknown | No outcome recorded |
| Phase 2 | NCT00162305 Comparator | Apr → Aug 2005 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 2/37 trials | ||||||
| Phase 2/3 | NCT07469722 Background | Mar 2026 → Jan 2028 expected | congestive heart failure | Hospital de Clinicas de Porto Alegre | Not yet recruiting | No outcome recorded |
| Phase 2/3 | NCT05986136 Comparator | Aug 2023 → Aug 2027 expected | inflammatory bowel disease | Mostafa Bahaa | Recruiting | No outcome recorded |
| Phase 2/3 | NCT05162690 Comparator | May 2022 → Dec 2023 | diabetic polyneuropathy | Post Graduate Institute of Medical Education and Research, Chandigarh | Unknown | No outcome recorded |
| Phase 2/3 | NCT05241431 Comparator | Feb 2022 → Mar 2024 | aortic valve stenosis, intrinsic cardiomyopathy | University of Aarhus | Unknown | No outcome recorded |
| Phase 2/3 | NCT05424315 Comparator | Oct 2021 → Apr 2022 | myocardial infarction | Omar Younis | Completed | No outcome recorded |
| Phase 2/3 | NCT05998837 Comparator | Apr 2021 → Sep 2024 | chronic kidney disease, hypertensive disorder, type 2 diabetes mellitus | IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy | Completed | No outcome recorded |
| Phase 2/3 | NCT00663260 Comparator | Jun 2008 → Dec 2009 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 341 trials | ||||||
| Phase 3 | NCT07624305 Comparator | Sep 2026 → Jul 2030 expected | chronic kidney disease | AstraZeneca | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07392151 Background | Feb 2026 → Oct 2029 expected | coronary atherosclerosis, prediabetes syndrome | Michael Mæng | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07025629 Comparator | Dec 2025 → Jan 2029 expected | chronic kidney disease | Assistance Publique - Hôpitaux de Paris | Recruiting | No outcome recorded |
| Phase 3 | NCT07082114 Comparator | Jul 2025 → Feb 2027 expected | type 2 diabetes mellitus | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | Recruiting | No outcome recorded |
| Phase 3 | NCT06677060 Background | Mar 2025 → Dec 2029 expected | heart failure | AstraZeneca | Recruiting | No outcome recorded |
| Phase 3 | NCT06742723 Background | Mar 2025 → Dec 2029 expected | chronic kidney disease | AstraZeneca | Recruiting | No outcome recorded |
| Phase 3 | NCT06820567 Comparator | Mar 2025 → Mar 2026 overdue | chronic kidney disease, type 2 diabetes mellitus | Assiut University | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT06317051 Comparator | Dec 2024 → Jul 2026 overdue | HIV infectious disease | Kirby Institute | Active not recruiting | No outcome recorded |
| Phase 3 | NCT06589765 Comparator | Sep 2024 → May 2026 | type 2 diabetes mellitus | Shandong Suncadia Medicine Co., Ltd. | Completed | No outcome recorded |
| Phase 3 | NCT06576375 Comparator | Sep 2024 → Jan 2025 overdue | polycystic ovary syndrome | Future University in Egypt | Recruiting | No outcome recorded |
| Phase 3 | NCT06535529 Comparator | Aug 2024 → Aug 2025 overdue | heart failure | Helwan University | Recruiting | No outcome recorded |
| Phase 3 | NCT06415773 Comparator | Jun 2024 → Jun 2025 | type 2 diabetes mellitus | HighTide Biopharma Pty Ltd | Completed | No outcome recorded |
| Phase 3 | NCT05852704 Comparator | Apr 2024 → Dec 2027 expected | atrial fibrillation, coronary artery disorder | Region Örebro County | Recruiting | No outcome recorded |
| Phase 3 | NCT06268873 Comparator | Mar 2024 → Feb 2028 expected | chronic kidney disease | AstraZeneca | Active not recruiting | No outcome recorded |
| Phase 3 | NCT06421870 Comparator | Mar 2024 → May 2025 | chronic kidney disease | Ain Shams University | Unknown | No outcome recorded |
| Phase 3 | NCT05886088 Comparator | Feb 2024 → May 2026 overdue | type 2 diabetes mellitus | EMS | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT06192108 Comparator | Jan 2024 → Sep 2025 | type 2 diabetes mellitus | Eli Lilly and Company | Completed | No outcome recorded |
| Phase 3 | NCT06087835 Comparator | Nov 2023 → Feb 2027 expected | chronic kidney disease | AstraZeneca | Active not recruiting | No outcome recorded |
| Phase 3 | NCT05558098 Comparator | Nov 2022 → Oct 2023 | critical illness polyneuropathy, infectious disease with sepsis | Hospital Israelita Albert Einstein | Completed | No outcome recorded |
| Phase 3 | NCT05591235 Comparator | Nov → Dec 2022 | type 2 diabetes mellitus | Nanjing First Hospital, Nanjing Medical University | Unknown | No outcome recorded |
| Phase 3 | NCT05321706 Comparator | Jun 2022 → Sep 2028 expected | heart failure, kidney failure | Oslo University Hospital | Active not recruiting | No outcome recorded |
| Phase 3 | NCT06690723 Comparator | Jun 2022 → Sep 2024 | obstructive sleep apnea syndrome | University Malaysia Sarawak | Completed | No outcome recorded |
| Phase 3 | NCT05174052 Comparator | Jun 2022 → Apr 2027 expected | atrial fibrillation, diabetes mellitus | University of Oklahoma | Recruiting | No outcome recorded |
| Phase 3 | NCT05957887 Comparator | Apr 2022 → Mar 2025 | ST-elevation myocardial infarction | Mohamed Nabil Elkholy | Unknown | No outcome recorded |
| Phase 3 | NCT05776043 Comparator | Mar 2022 → Sep 2024 | heart failure | Medical University of Warsaw | Unknown | No outcome recorded |
| Phase 3 | NCT05601336 Comparator | Jan 2022 → Jul 2023 | — | Beni-Suef University | Unknown | No outcome recorded |
| Phase 3 | NCT05226897 Background | Jul 2021 → Oct 2022 | type 2 diabetes mellitus | Yooyoung Pharmaceutical Co., Ltd. | Unknown | No outcome recorded |
| Phase 3 | NCT05308160 Comparator | Jun 2021 → Jun 2023 | fatty liver disease | National Taiwan University Hospital | Unknown | No outcome recorded |
| Phase 3 | NCT04885712 Background | May 2021 → Sep 2022 | type 2 diabetes mellitus | Boryung Pharmaceutical Co., Ltd | Completed | No outcome recorded |
| Phase 3 | NCT05159882 Comparator | Apr 2021 → Sep 2022 | type 2 diabetes mellitus | Newsoara Biopharma Co., Ltd. | Unknown | No outcome recorded |
| Phase 3 | NCT04350593 Comparator | Apr 2020 → Mar 2021 | COVID-19 | Saint Luke's Health System | Completed | No outcome recorded |
| Phase 3 | NCT04170998 Background | Jan 2020 → Jun 2021 | type 2 diabetes mellitus | Dong-A ST Co., Ltd. | Completed | No outcome recorded |
| Phase 3 | NCT02984644 Comparator | Sep 2017 → Nov 2018 | type 2 diabetes mellitus | The University of Texas Health Science Center at San Antonio | Completed | No outcome recorded |
| Phase 3 | NCT02681094 Comparator | Feb 2016 → Jul 2017 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT02597049 Background | Nov 2015 → Feb 2017 | type 2 diabetes mellitus | Eli Lilly and Company | Completed | No outcome recorded |
| Phase 3 | NCT02592421 Comparator | Oct 2015 → Oct 2018 | type 2 diabetes mellitus | The University of Texas Health Science Center at San Antonio | Completed | No outcome recorded |
| Phase 3 | NCT02338193 Comparator | Sep 2015 → Feb 2019 | — | Woman's | Completed | No outcome recorded |
| Phase 3 | NCT02518945 Comparator | Aug → Dec 2015 | type 1 diabetes mellitus | University at Buffalo | Completed | No outcome recorded |
| Phase 3 | NCT02383238 Comparator | Mar 2014 → Oct 2015 | type 2 diabetes mellitus | University of Erlangen-Nürnberg Medical School | Completed | No outcome recorded |
| Phase 3 | NCT01619059 Background | Jun 2012 → Jun 2014 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 3 | NCT00984867 Comparator | Oct 2009 → Mar 2011 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 469 trials | ||||||
| Phase 4 | NCT07323524 Comparator | May 2026 → Jul 2029 expected | lupus nephritis | Brigham and Women's Hospital | Recruiting | No outcome recorded |
| Phase 4 | NCT07436663 Comparator | Feb 2026 → Nov 2027 expected | breast cancer | Tanta University | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07351864 Background | Jan → Apr 2026 overdue | heart failure | Mansoura University | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07147114 Background | Nov 2025 → Sep 2027 expected | mild heart failure, pulmonary hypertension | Gachon University Gil Medical Center | Recruiting | No outcome recorded |
| Phase 4 | NCT06954090 Comparator | Nov 2025 → Nov 2026 expected | diabetic kidney disease, proteinuria, type 2 diabetes mellitus | Steno Diabetes Center Copenhagen | Enrolling by invitation | No outcome recorded |
| Phase 4 | NCT06922656 Comparator | Sep 2025 → Sep 2026 expected | type 1 diabetes mellitus | Dasman Diabetes Institute | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT06972732 Background | Jun 2025 → Oct 2026 expected | type 2 diabetes mellitus | Boryung Pharmaceutical Co., Ltd | Recruiting | No outcome recorded |
| Phase 4 | NCT06676384 Comparator | Feb 2025 → Aug 2029 expected | IgA glomerulonephritis, chronic kidney disease, immunoglobulin A vasculitis | Christian Medical College, Vellore, India | Recruiting | No outcome recorded |
| Phase 4 | NCT06562582 Comparator | Jan 2025 → Dec 2027 expected | myocardial infarction | Vastra Gotaland Region | Recruiting | No outcome recorded |
| Phase 4 | NCT07325435 Comparator | Dec 2024 → Dec 2027 expected | type 2 diabetes mellitus | MaryAnn Banerji | Active not recruiting | No outcome recorded |
| Phase 4 | NCT06491680 Comparator | Sep 2024 → Oct 2025 overdue | breast cancer | Helwan University | Recruiting | No outcome recorded |
| Phase 4 | NCT06449235 Comparator | Sep 2024 → Apr 2025 overdue | type 2 diabetes mellitus | Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT06364930 Comparator | Mar 2024 → Oct 2030 expected | chronic hepatitis B virus infection | Chinese University of Hong Kong | Recruiting | No outcome recorded |
| Phase 4 | NCT06327815 Comparator | Mar 2024 → Jun 2025 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 4 | NCT06642623 Comparator | Jan 2024 → Sep 2029 expected | cardiovascular disorder, kidney disorder, type 2 diabetes mellitus | Yonsei University | Recruiting | No outcome recorded |
| Phase 4 | NCT05989503 Comparator | Aug 2023 → Jul 2025 | symptomatic heart failure | University of Porto | Completed | No outcome recorded |
| Phase 4 | NCT05966818 Comparator | Aug 2023 → Jan 2024 | nephrotic syndrome | Ain Shams University | Unknown | No outcome recorded |
| Phase 4 | NCT06560801 Comparator | Jul 2023 → Oct 2026 expected | chronic kidney disease | University of Erlangen-Nürnberg Medical School | Recruiting | No outcome recorded |
| Phase 4 | NCT05788276 Comparator | May 2023 → Jun 2028 expected | kidney failure | Oslo University Hospital | Recruiting | No outcome recorded |
| Phase 4 | NCT07363707 Comparator | May → Aug 2023 | NAFLD1 | Beni-Suef University | Completed | No outcome recorded |
| Phase 4 | NCT06127433 Comparator | Mar 2023 → May 2024 | — | Sun Yat-sen University | Unknown | No outcome recorded |
| Phase 4 | NCT06721442 Comparator | Jan → Dec 2023 | cardiac rhythm disease, type 2 diabetes mellitus | Beneficência Portuguesa de São Paulo | Completed | No outcome recorded |
| Phase 4 | NCT05704088 Comparator | Oct 2022 → Jan 2024 | lupus nephritis | Mansoura University | Completed | No outcome recorded |
| Phase 4 | NCT05748925 Comparator | Oct 2022 → Jan 2024 | lupus nephritis, systemic lupus erythematosus | Mansoura University | Completed | No outcome recorded |
| Phase 4 | NCT05390892 Comparator | Sep 2022 → Mar 2029 expected | atherosclerotic cardiovascular disease, type 2 diabetes mellitus | Brigham and Women's Hospital | Recruiting | No outcome recorded |
| Phase 4 | NCT05735197 Comparator | Sep 2022 → Aug 2023 | chronic kidney disease, metabolic bone disorder | Mansoura University | Completed | No outcome recorded |
| Phase 4 | NCT05459701 Comparator | May 2022 → Jun 2024 | NAFLD1, type 2 diabetes mellitus | Rehab Werida | Completed | No outcome recorded |
| Phase 4 | NCT05194592 Comparator | Jan 2022 → Dec 2024 | type 2 diabetes mellitus | Wonju Severance Christian Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT06281899 Background | Jan 2022 → Dec 2024 | chronic kidney disease, type 2 diabetes mellitus | Anemia Working Group Romania | Unknown | No outcome recorded |
| Phase 4 | NCT05225077 Comparator | Jan → Dec 2022 | chronic kidney disease | Dong-A University | Unknown | No outcome recorded |
| Phase 4 | NCT03423355 Comparator | Sep 2021 → Mar 2023 | type 2 diabetes mellitus | University Hospital Tuebingen | Withdrawn | No outcome recorded |
| Phase 4 | NCT05797935 Comparator | Aug 2021 → Dec 2022 | pancreas disorder | Post Graduate Institute of Medical Education and Research, Chandigarh | Completed | No outcome recorded |
| Phase 4 | NCT04792190 Comparator | Jul 2021 → Mar 2023 | atrial fibrillation | University of Rochester | Completed | No outcome recorded |
| Phase 4 | NCT04796428 Comparator | Jun 2021 → Dec 2023 | type 2 diabetes mellitus | Center for Outcomes Research and Clinical Epidemiology, Italy | Unknown | No outcome recorded |
| Phase 4 | NCT04869124 Comparator | Feb 2021 → Sep 2024 | congestive heart failure | Frank Ruschitzka | Completed | No outcome recorded |
| Phase 4 | NCT04706637 Comparator | Feb 2021 → Jan 2022 | metabolic bone disorder, type 2 diabetes mellitus | Kyung Hee University Hospital at Gangdong | Unknown | No outcome recorded |
| Phase 4 | NCT04696185 Comparator | Jan 2021 → Dec 2024 | aortic valve stenosis | Spanish Society of Cardiology | Completed | No outcome recorded |
| Phase 4 | NCT04385589 Comparator | May → Dec 2020 | heart failure | Assiut University | Completed | No outcome recorded |
| Phase 4 | NCT03499704 Comparator | Feb 2020 → Jan 2024 | type 2 diabetes mellitus | Celltrion Pharm, Inc. | Completed | No outcome recorded |
| Phase 4 | NCT04196231 Comparator | Nov 2019 → Sep 2020 | type 2 diabetes mellitus | University of Campania Luigi Vanvitelli | Completed | No outcome recorded |
| Phase 4 | NCT04080518 Comparator | Nov 2019 → Nov 2021 | diabetes mellitus, heart failure | National Heart Centre Singapore | Completed | No outcome recorded |
| Phase 4 | NCT02981966 Comparator | May 2019 → Apr 2022 | type 2 diabetes mellitus | The University of Texas Health Science Center at San Antonio | Completed | No outcome recorded |
| Phase 4 | NCT03721874 Comparator | Apr 2019 → Jun 2021 | prediabetes syndrome | Maastricht University | Completed | No outcome recorded |
| Phase 4 | NCT03887416 Comparator | Apr 2019 → Feb 2020 | type 2 diabetes mellitus | LM Diagnósticos S.L. | Unknown | No outcome recorded |
| Phase 4 | NCT03871621 Comparator | Apr 2019 → May 2022 | type 2 diabetes mellitus | Mackay Memorial Hospital | Completed | No outcome recorded |
| Phase 4 | NCT03782259 Comparator | Feb 2019 → Nov 2022 | type 2 diabetes mellitus | University of Washington | Completed | No outcome recorded |
| Phase 4 | NCT04219124 Comparator | Sep 2018 → Jan 2020 | type 2 diabetes mellitus | University of Leicester | Completed | No outcome recorded |
| Phase 4 | NCT03338855 Comparator | Mar 2018 → Nov 2019 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 4 | NCT03331289 Comparator | Feb 2018 → Mar 2022 | type 2 diabetes mellitus | The University of Texas Health Science Center at San Antonio | Completed | No outcome recorded |
| Phase 4 | NCT02965443 Comparator | Feb 2018 → Feb 2020 | type 2 diabetes mellitus | University Hospital Tuebingen | Terminated | No outcome recorded |
| Phase 4 | NCT02981069 Comparator | Dec 2017 → Jul 2022 | type 2 diabetes mellitus | The University of Texas Health Science Center at San Antonio | Completed | No outcome recorded |
| Phase 4 | NCT03202563 Comparator | Aug 2017 → Jul 2018 | type 2 diabetes mellitus | LG Chem | Completed | No outcome recorded |
| Phase 4 | NCT03007329 Comparator | Mar 2017 → Nov 2019 | fatty liver disease, type 2 diabetes mellitus | Medical University of Vienna | Completed | No outcome recorded |
| Phase 4 | NCT03030235 Comparator | Mar 2017 → Aug 2021 | diastolic heart failure | Saint Luke's Health System | Completed | No outcome recorded |
| Phase 4 | NCT02956811 Comparator | Feb 2017 → Mar 2019 | type 2 diabetes mellitus | University of Dundee | Completed | No outcome recorded |
| Phase 4 | NCT02887677 Comparator | Oct 2016 → Jun 2019 | diabetes mellitus | Hellenic Society for Medical Education | Terminated | No outcome recorded |
| Phase 4 | NCT02653482 Comparator | Mar 2016 → Jun 2019 | systolic heart failure | Saint Luke's Health System | Completed | No outcome recorded |
| Phase 4 | NCT02796170 Comparator | Mar 2016 → Aug 2019 | essential hypertension, type 2 diabetes mellitus | Tulane University School of Medicine | Completed | No outcome recorded |
| Phase 4 | NCT02475070 Comparator | Jan 2016 → Jun 2017 | type 2 diabetes mellitus | Lund University | Completed | No outcome recorded |
| Phase 4 | NCT02610088 Comparator | Nov 2015 → Jul 2018 | diabetes mellitus | Seoul National University Bundang Hospital | Completed | No outcome recorded |
| Phase 4 | NCT02433678 Comparator | Nov 2015 → Mar 2018 | type 2 diabetes mellitus | University at Buffalo | Completed | No outcome recorded |
| Phase 4 | NCT02471404 Comparator | Sep 2015 → Mar 2017 | type 2 diabetes mellitus | AstraZeneca | Completed | No outcome recorded |
| Phase 4 | NCT02528019 Comparator | Aug 2015 → Aug 2017 | — | Kurume University | Unknown | No outcome recorded |
| Phase 4 | NCT02914691 Comparator | Aug 2015 → Jul 2017 | diabetic kidney disease, type 2 diabetes mellitus | Peter Rossing | Completed | No outcome recorded |
| Phase 4 | NCT02397421 Comparator | Mar 2015 → Aug 2017 | diabetes mellitus, heart failure | University of Dundee | Completed | No outcome recorded |
| Phase 4 | NCT02338921 Comparator | Jan 2015 → Nov 2021 | type 2 diabetes mellitus | Seoul National University Bundang Hospital | Completed | No outcome recorded |
| Phase 4 | NCT02501616 Comparator | Dec 2014 → Dec 2015 | type 2 diabetes mellitus | Seoul National University Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT03178591 Comparator | Oct 2014 → Jul 2018 | coronary artery disorder, type 2 diabetes mellitus | Chiang Mai University | Completed | No outcome recorded |
| Phase 4 | NCT02211742 Comparator | Aug 2014 → Jul 2016 | glucose intolerance | Medical University Innsbruck | Completed | No outcome recorded |
| Phase not applicable25 trials | ||||||
| — | NCT07331220 Background | Dec 2026 → Dec 2028 expected | diastolic heart failure | Nanjing First Hospital, Nanjing Medical University | Not yet recruiting | No outcome recorded |
| — | NCT07694596 Background | Jun 2026 → Apr 2028 expected | cognitive disorder, type 2 diabetes mellitus | University of Primorska | Active not recruiting | No outcome recorded |
| — | NCT07391267 Background | Feb 2026 → Dec 2028 expected | chronic kidney disease, metabolic dysfunction-associated steatotic liver disease | Institute of Liver and Biliary Sciences, India | Not yet recruiting | No outcome recorded |
| — | NCT07335900 Background | Dec 2025 → Dec 2026 expected | aortic valve stenosis | RenJi Hospital | Recruiting | No outcome recorded |
| — | NCT07070765 Comparator | Dec 2025 → Oct 2028 expected | breast cancer | University of Aberdeen | Recruiting | No outcome recorded |
| — | NCT07491718 Comparator | Aug 2025 → Aug 2028 expected | Tako-tsubo cardiomyopathy | University of Edinburgh | Recruiting | No outcome recorded |
| — | NCT06930092 Comparator | Aug 2025 → Apr 2028 expected | cardiomyopathy | Seoul National University Hospital | Recruiting | No outcome recorded |
| — | NCT06778330 Comparator | Jan → Aug 2025 | moderate heart failure | Fayoum University | Completed | No outcome recorded |
| — | NCT07303556 Background | Dec 2024 → Jul 2025 overdue | heart failure, hypertensive disorder, type 2 diabetes mellitus | Nazarbayev University | Active not recruiting | No outcome recorded |
| — | NCT05993897 Comparator | Aug 2024 → Jun 2025 | atrial fibrillation | Aswan University | Completed | No outcome recorded |
| — | NCT06510270 Comparator | Aug 2024 → Aug 2025 overdue | heart failure | Aswan University | Not yet recruiting | No outcome recorded |
| — | NCT06398977 Comparator | Mar 2024 → Jun 2026 overdue | impaired renal function disease | Sichuan Academy of Medical Sciences | Recruiting | No outcome recorded |
| — | NCT06009874 Comparator | Oct 2023 → Aug 2026 overdue | myocardial infarction | Mohammad Hussien Tantawy Soliman | Recruiting | No outcome recorded |
| — | NCT06241638 Background | Jul 2022 → Jun 2023 | diabetes mellitus | Al-Balqa Applied University | Completed | No outcome recorded |
| — | NCT05335629 Comparator | Jun 2022 → Oct 2023 | myocardial infarction, type 2 diabetes mellitus | Ain Shams University | Completed | No outcome recorded |
| — | NCT05418465 Comparator | Jan → Dec 2022 | diabetic kidney disease | The First Affiliated Hospital of Dalian Medical University | Unknown | No outcome recorded |
| — | NCT05042505 Comparator | Jan 2022 → Dec 2024 | diabetes mellitus | Medanta, The Medicity, India | Completed | No outcome recorded |
| — | NCT05045274 Comparator | Dec 2021 → Jun 2022 | ST-elevation myocardial infarction, systolic heart failure | Assiut University | Unknown | No outcome recorded |
| — | NCT03961659 Comparator | May 2019 → Aug 2020 | cognitive impairment with or without cerebellar ataxia, obesity disorder, type 2 diabetes mellitus | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | Unknown | No outcome recorded |
| — | NCT06611904 Comparator | Feb 2018 → Feb 2022 overdue | arteriosclerosis disorder, proteinuria | Attikon Hospital | Active not recruiting | No outcome recorded |
| — | NCT02962492 Comparator | Nov 2016 → Feb 2021 | — | University at Buffalo | Completed | No outcome recorded |
| — | NCT02879409 Background | Nov 2016 → Oct 2023 overdue | type 2 diabetes mellitus | Weill Cornell Medical College in Qatar | Active not recruiting | No outcome recorded |
| — | NCT02777073 Comparator | Mar → Dec 2016 | type 1 diabetes mellitus | University at Buffalo | Completed | No outcome recorded |
| — | NCT02613897 Comparator | Jan 2016 → Jun 2018 | type 2 diabetes mellitus | The University of Texas Health Science Center at San Antonio | Completed | No outcome recorded |
| — | NCT02969798 Comparator | Jan 2014 → Dec 2026 expected | glucose intolerance, prediabetes syndrome, type 2 diabetes mellitus | The University of Texas Health Science Center at San Antonio | Recruiting | No outcome recorded |
Press releases naming this drug 2 releases
| Date | Issuer | Release |
|---|---|---|
| 2024-06-12 | AstraZeneca | Farxiga approved in the US for the treatment of paediatric type-2 diabetes astrazeneca.com ↗ |
| 2023-11-03 | AstraZeneca | Zibotentan/dapagliflozin combination demonstrated significant albuminuria reduction in patients with chronic kidney disease and proteinuria in ZENITH-CKD Phase IIb trial astrazeneca.com ↗ |
Evidence & citations 24 cited values
Every value below carries the sentence it was read from. 621 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Dapagliflozin | “The study intervention will be a heart failure with reduced ejection fraction (HFrEF) polypill consisting of bisoprolol (beta-blocker), losartan (ARB), eplerenone (MRA), and...” NCT07569640 ↗607“HFrEF polypill strength 1: bisoprolol 2.5 mg + losartan 25 mg + eplerenone 25 mg + dapagliflozin 10 mg; HFrEF polypill strength 2: bisoprolol 5 mg + losartan 50 mg + eplerenone...” NCT06831864 ↗ “BACKGROUND AND OBJECTIVES: To establish pharmacokinetic bioequivalence and assess the safety of a single-dose administration of fixed-dose combination (FDC) tablet containing...” PMID 42270920 ↗ Jun 2026 “A total of 235 patients with inadequate response to metformin (≥1000 mg/day) plus linagliptin (5 mg/day) were randomized to receive either dapagliflozin/linagliptin fixed-dose...” PMID 39375869 ↗ Oct 2024 “Participants randomized to the intervention group will receive empagliflozin (10 mg once daily, with optional titration to 25 mg according to clinical judgement and...” NCT07694596 ↗ “Patients with acute decompensated HF will be open-label randomly assigned to be treated with or without SGLT2 inhibitors (either empagliflozin 10 mg once daily or dapagliflozin...” NCT06142474 ↗ “This clinical trial will evaluate whether combination therapy with Dapagliflozin + Macitentan improves outcomes compared to Dapagliflozin + placebo in patients with combined...” NCT07147114 ↗ “The primary objective of the study is to examine the effect of combination therapy with pioglitazone (15 mg) plus dapagliflozin (10 mg) versus placebo on hospitalization for...” NCT03794518 ↗ “The specific agent (e.g., dapagliflozin or empagliflozin) and dose will be selected based on safety data and clinical guidelines applicable to patients with end-stage renal...” NCT06929169 ↗ “Sequential discontinuation of angiotensin receptor-neprilysin inhibitor (ARNI; e.g., sacubitril/valsartan) and sodium-glucose cotransporter-2 inhibitor (SGLT2i; e.g.,...” NCT07631156 ↗ “Dulaglutide and Dapagliflozin Combination Concurrently Improves the Endothelial Glycocalyx and Vascular and Myocardial Function in Patients with T2DM and Albuminuria vs. DPP-4i.” PMID 39768420 ↗ Dec 2024 “Dapagliflozin is a novel highly selective SGLT2 inhibitor that improves glycemic control by reducing renal glucose reabsorption leading to urinary glucose excretion.” NCT02338193 ↗ “All patients will be started on an SGLT2i (Empagliflozin or Dapagliflozin) and a betablocker (Metoprolol, Bisoprolol or Carvedilol) right after study inclusion.” NCT05637853 ↗ “Chemical Name: Sodium-Glucose Co-Transporter-2 (SGLT2) Inhibitors (e.g., Canagliflozin, Dapagliflozin, Empagliflozin, Ertugliflozin) Class: SGLT2 Inhibitors” NCT06449235 ↗ “Patients will be randomized 1:1 in blocks of 6 patients to either Dapagliflozin 10 mg daily or placebo within 1 months prior to the scheduled TAVR therapy.” NCT05241431 ↗ “the study aims to investigate the effect of dapagliflozin, a SGLT2 inhibitor, on glucose flux, lipolysis and exercise in patients with type 2 diabetes.” NCT04219124 ↗ “In this study, patients received standard clinical doses (e.g., dapagliflozin 5-10 mg once daily or empagliflozin 10-25 mg once daily) for 6 months.” NCT07539584 ↗ “The investigators wish to determine whether dapagliflozin (SGLT2 inhibitor) taken daily during chemotherapy will reduce the rate of cardiotoxicity.” NCT07070765 ↗ “Assessing the Efficacy of Dapagliflozin as a Vasculoprotective Treatment in Septic Shock Patients With Microcirculatory Dysfunction” NCT07488689 ↗ “receive combination of metformin, pioglitazone, and an SGLT2 inhibitor (empagliflozin or dapagliflozin or canagliflozin)” NCT04419337 ↗ “adding dapagliflozin or empagliflozin 10 mg once daily to post-TxC routine compared with no intervention for 6-8 months.” NCT06147271 ↗ “Drug: Dapagliflozin and Sitagliptin Single oral administration of Dapagliflozin and Sitagliptin after an overnight fast” NCT05403281 ↗ “On the basis of standard cancer treatment, take dapagliflozin for at least three months, once a day, 10 mg each time.” NCT07272057 ↗ “where subjects will either begin study provided dapagliflozin 10 mg or continue on their regularly prescribed SGLT2i” NCT06150924 ↗ “Dapagliflozin, an SGLT2 inhibitor, targets hyperglycaemia in type 2 diabetes by increasing renal glucose excretion.” PMID 23668478 ↗ Jun 2013 “The first group is the Dapagliflozin group, which will get Dapagliflozin 10mg once a day every morning for 14 days.” NCT06615674 ↗ “MEDI0382 in Combination With Dapagliflozin and Metformin in Overweight/Obese Participants With Type 2 Diabetes” NCT03444584 ↗ “Oral ACEI/ARB (e.g., valsartan capsules 80mg qd or 150mg qd) + Dapagliflozin (10 or 20mg orally once a day)” NCT07356388 ↗ “Investigations were performed before and after a 12-week treatment with the SGLT2 inhibitor, dapagliflozin.” PMID 32514450 ↗ Nov 2019 “ATB-U101 is a fixed-dose combination tablet containing Olmesartan medoxomil 40 mg and Dapagliflozin 10 mg.” NCT07590466 ↗ “Participants will receive oral AZD9977 Dose A capsule and 10 mg dapagliflozin tablet in fasted condition.” NCT04798222 ↗ “either 12 months of oral SGLT2 inhibitor therapy (Dapagliflozin 10 mg once daily) or a matching placebo” NCT07682350 ↗ “SGLT2 inhibitors (dapagliflozin, empagliflozin, canagliflozin) - recommended for people with T2D + CKD” NCT07391267 ↗ “Evaluation of the Pharmacokinetic Interaction Between Lobeglitazone and Dapagliflozin at Steady State.” PMID 31992459 ↗ Jan 2020 “Maximal labelled or tolerated dose of ACEi/ ARB and a steady dose of SGLT2i (10mg/d of dapagliflozin).” NCT06676384 ↗ “Single oral dose A51R1(Dapagliflozin) 10 mg tablet and A51R2(Linagliptin) 5 mg tablet taken together” NCT04972539 ↗ “For the SGLT2 inhibitor group, empagliflozin 10mg or dapagliflozin 10mg once daily is administered.” NCT05975528 ↗ “the second group will receive an SGLT2 inhibitor (dapagliflozin or empagliflozin 10 mg once daily)” NCT07563647 ↗ “empagliflozin (10 mg daily) or dapagliflozin (10 mg daily), depending on formulary coverage” NCT05278962 ↗ “The intervention, dapagliflozin will be administered 10mg per oral daily for two weeks.” NCT04400760 ↗ “The glucose-lowering component will consist of dapagliflozin at a fixed dose of 10 mg.” NCT07679828 ↗ “the SGLT2 inhibitor (dapagliflozin 10 mg once daily or empagliflozin 10 mg once daily)” NCT07572032 ↗ “CKD-380(Dapagliflozin) 10mg Tab.1T single oral administration under fasting condition” NCT03601910 ↗ “10 mg dapagliflozin/100 mg sitagliptin FDC (Treatment A) with their ICs (Treatment B)” PMID 39179458 ↗ Aug 2024 “Group dapagliflozin: stander treatment of Type 2 diabetes mellitus plus dapagliflozin” NCT06117137 ↗ “Sodium-glucose co-transporter 2 inhibitor (SGLT2i): Farxiga® (dapagliflozin) 5 mg” NCT04697485 ↗ “Withdrawal of spironolactone or eplerenone and dapagliflozin or empagliflozin” NCT06091475 ↗ “Forxiga™ 10mg, dapagliflozin 10mg, oral, once daily for 7 days (70 mg total)” NCT04035031 ↗ “Dapagliflozin 10 mg once daily (QD) or Empagliflozin 10 mg once daily (QD)” NCT07105917 ↗ “Dapagliflozin will be started at 10 mg daily per oral administration” NCT04196231 ↗ “SGLT2 inhibitor: dapagliflozin or empagliflozin at 10 mg per day” NCT07513883 ↗ “Each component of Gemigliptin 50mg QD and Dapagliflozin 10mg QD” NCT04544319 ↗ “Xigduo (metformin 1000mg + dapagliflozin 10mg) saxagliptin 5mg” NCT02946632 ↗ “Dapagliflozin 10mg +sitagliptin 100mg combination drug” NCT06875193 ↗ “to receive dapagliflozin (10 mg once daily) or placebo” PMID 32970396 ↗ Sep 2020 “an SGLT2 inhibitor (empagliflozin or dapagliflozin)” NCT06930092 ↗ “subgroup 3A- addition of dapagliflozin 10 mg/day” NCT03804411 ↗ “Either empagliflozin or dapagliflozin 10 mg/day” NCT05989503 ↗ “Empagliflozin, dapagliflozin, or canagliflozin” NCT05390892 ↗ “Dapagliflozin/Metformin (Xigduo XR) 10/1000mg” NCT03826641 ↗ “SGLT2i can be dapagliflozin or empagliflozin.” NCT07331220 ↗ “Dapagliflozin (Forxiga), 10 mg tablet daily.” NCT07392151 ↗ “10 mg of Dapagliflozin orally once daily” NCT05993897 ↗ “Metformin, Dapagliflozin and Saxagliptin” NCT03700801 ↗ “such as dapagliflozin and empagliflozin” NCT07335900 ↗ “Dapagliflozin (SGLTII-Inhibitor, 10 mg)” NCT04027023 ↗ “Dapagliflozin 10mg + Linagliptin 5mg” NCT07034781 ↗ “Dapagliflozin 10mg + Linagliptin 5mg” NCT07044765 ↗ “SGLT-2 inhibitor (dapagliflozin)” NCT05965934 ↗ “Dapagliflozin (Forxiga) 10mg” NCT04084184 ↗ “Dapagliflozin 10mg (Farxiga)” NCT05541484 ↗ “dapagliflozin (5-10mg daily)” NCT02528019 ↗ “dapagliflozin (10 mg daily)” NCT05346653 ↗ “dapagliflozin (Farxiga®)” NCT07325435 ↗ “Dapagliflozin 10 mg” NCT06647745 ↗ “Drug: Dapagliflozin” NCT03199053 ↗ “Dapagliflozin 10mg” NCT05411965 ↗ “Dapagliflozin” NCT03887416 ↗ “Dapagliflozin” NCT02919059 ↗ “dapagliflozin” NCT05737186 ↗ “dapagliflozin” NCT04882358 ↗ |
| Known as | A51R1 | “Single oral dose A51R1(Dapagliflozin) 10 mg tablet and A51R2(Linagliptin) 5 mg tablet taken together” NCT04972539 ↗ |
| Known as | ATB-1012 | “ATB-1011 (Olmetec, Olmesartan medoxomil 40 mg) and ATB-1012 (Forxiga, Dapagliflozin 10 mg) will be co-administered as a single oral dose under fasting conditions (minimum 10...” NCT07590466 ↗ |
| Known as | BMS -512148 | “The purpose of this study is to learn if a combination of BMS-477118 (Saxagliptin) and BMS -512148 (Dapagliflozin) added to Metformin can improve (decrease) Glycosylated...” NCT01606007 ↗ |
| Known as | BMS-51248 | “The purpose of this clinical research study is to learn if initiating treatment with BMS-51248 (Dapagliflozin) in combination with metformin XR can improve diabetes control” NCT00643851 ↗ |
| Known as | CKD-380 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT03601910 ↗ |
| Known as | DAPA | “Dapagliflozin (DAPA), a sodium-glucose co-transporter 2 inhibitor (SGLT2-I), has proven to be an effective hyperglycemic suppressor due to its role in inhibiting the...” NCT05792540 ↗28“The overarching hypothesis of this study is that vildagliptin (vilda) as add on therapy to metformin (met) in Egyptian type 2 diabetic obese patient will produce an equal, if...” NCT07077525 ↗ “FDA-approved drug dapagliflozin (Dapa) improves submaximal exercise endurance and skeletal muscle oxidative phosphorylation capacity (SkM OxPhos) in patients with heart failure...” NCT04956809 ↗ “AIMS: To investigate the potential synergistic effects of combined exenatide (EXE) and dapagliflozin (DAPA) versus (PLAC) placebo and DAPA on hepatocellular lipid (HCL)...” PMID 33464703 ↗ Feb 2021 “treatment with Dapagliflozin (DAPA) for 6 months will improve pulmonary capillary wedge pressure (PCWP) during exercise in heart failure/preserved ejection fraction (HFpEF) and...” NCT04730947 ↗ “To investigate the effect of the SGLT2 inhibitor, dapagliflozin (DAPA), on cardiac function and the metabolic and hormonal response to moderate exercise in people with type 2 diabetes.” PMID 36274035 ↗ Mar 2023 “We evaluated the effects of dapagliflozin (DAPA) on measures of cardiovascular autonomic neuropathy (CAN), cardiac function, and glucose variability (GV) in T2D.” PMID 34024686 ↗ May 2021 “Dapagliflozin (DAPA) has shown renal and cardiometabolic benefits in nontransplanted patients with chronic kidney disease.” PMID 42102257 ↗ May 2026 “Dapagliflozin (DAPA) is an inhibitor of sodium-glucose cotransporter 2 prescribed for type 2 diabetes mellitus.” PMID 30689697 ↗ Apr 2019 “The efficacy of once-weekly exenatide (EQW) and dapagliflozin (DAPA) alone and coadministered” PMID 34097062 ↗ Sep 2021 “Dapagliflozin (DAPA), a sodium-glucose cotransporter 2 (SGLT2) inhibitor” NCT06427226 ↗ “Effects of Dapagliflozin (Dapa) and Dapagliflozin-Saxagliptin” PMID 39865301 ↗ Jan 2025 “dapagliflozin (DAPA), 10 mg” PMID 35235659 ↗ Jun 2022 “Drug: Dapagliflozin (DAPA)” NCT07076615 ↗ “Dapagliflozin (DAPA)” NCT06748105 ↗ “Dapagliflozin (DAPA)” NCT06820567 ↗ “Dapagliflozin (DAPA)” NCT06812429 ↗ “Dapagliflozin (DAPA)” NCT07614230 ↗ “Dapagliflozin (DAPA)” NCT07120828 ↗ “Dapagliflozin (DAPA)” NCT07539259 ↗ “Dapagliflozin (DAPA)” NCT06922656 ↗ “Dapagliflozin (DAPA)” NCT07082114 ↗ “Dapagliflozin (DAPA)” NCT06897605 ↗ “Dapagliflozin (DAPA)” NCT06759077 ↗ “Dapagliflozin (DAPA)” NCT06721442 ↗ “Dapagliflozin (DAPA)” NCT06759909 ↗ “Dapagliflozin (DAPA)” NCT06626737 ↗ “Dapagliflozin (DAPA)” NCT07020377 ↗ “Dapagliflozin (DAPA)” NCT06907251 ↗ |
| Known as | dapagliflozin (Farxiga) | “dapagliflozin (Farxiga®)” NCT07325435 ↗ |
| Known as | Dapagliflozin 10mg (Farxiga) | “Dapagliflozin 10mg (Farxiga)” NCT05541484 ↗ |
| Known as | Dapagliflozin propanediol | “Dapagliflozin propanediol (FORXIGA) tablet: 10 mg once daily p.o. on top of recommended standard therapy, duration of administration: 12 weeks.” NCT04869124 ↗1“Dapagliflozin propanediol (FORXIGA™/FARXIGA™1)” NCT05764057 ↗ |
| Known as | Dapagliflozin/metformin IR FDC | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01535677 ↗ |
| Known as | dapagliflozine | “Intervention: Dapagliflozine 10 mg once daily tablet treatment or Empagliflozin10 mg once daily tablet treatment or Canagliflozin 100 mg once daily tablet treatment.” NCT04127084 ↗3“SGL2I(DAPAGLIFLOZINE at a dose (10 mg/day) orally” NCT06759077 ↗ “Drug: dapagliflozine” NCT07351864 ↗ |
| Known as | Dapagliglozin | “The 2019 DAPA-HF trial studied whether the addition of the SCLT-2 inhibitor dapagliglozin could benefit patients with heart failure with reduced ejection fraction (HFrEF),...” NCT04570865 ↗ |
| Known as | Diglifloz | “Dapagliflozin (Diglifloz) 10 mg orally once daily for 24 weeks and the standard therapy (ACEI or ARB).” NCT05966818 ↗ |
| Known as | Farxiga | “The investigational medicinal product (IMP) is Dapagliflozin 10 MG Oral Tablet [Farxiga] given once daily (film coated tablets, oral use).” NCT03887416 ↗17“Subjects receive once daily 10 mg of oral dapagliflozin (Farxiga) for 14 days (or until discharge).” NCT07273838 ↗ “The patients assigned to the Dapagliflozin group will take Farxiga Pill 10mg for 6 months.” NCT05194592 ↗ “Dapagliflozin 10 mg [Farxiga] for 3 months after catheter ablation of atrial fibrillation” NCT06111443 ↗ “Dapagliflozin therapy (Farxiga®, 10 mg tablets) is administered orally once daily” NCT06890143 ↗ “Sodium-glucose co-transporter 2 inhibitor (SGLT2i): Farxiga® (dapagliflozin) 5 mg” NCT04697485 ↗ “Drug: Dapagliflozin 10 milligrams [Farxiga]” NCT04591639 ↗ “Dapagliflozin 10 MG Oral Tablet [Farxiga]” NCT07025629 ↗ “Drug: Dapagliflozin 10 MG [Farxiga]” NCT05250752 ↗ “Drug: Dapagliflozin 10 MG [Farxiga]” NCT05719714 ↗ “Farxiga® (dapagliflozin) 10 mg” NCT07033585 ↗ “Dapagliflozin 10 MG [Farxiga]” NCT04620590 ↗ “Dapagliflozin 10 MG [Farxiga]” NCT04545411 ↗ “Dapagliflozin 10 MG [Farxiga]” NCT05225077 ↗ “Dapagliflozin 10 MG [Farxiga]” NCT04739215 ↗ “Dapagliflozin 10 MG [Farxiga]” NCT05179356 ↗ “Dapagliflozin Farxiga®” NCT05849766 ↗ “Dapagliflozin, Farxiga” NCT02551874 ↗ |
| Known as | FARXIGA1 | “Dapagliflozin propanediol (FORXIGA™/FARXIGA™1)” NCT05764057 ↗ |
| Known as | Forxiga | “each group was administered either a single dose of IN-C009 (FCDP, dapagliflozin 10mg/linagliptin 5 mg) (HK inno.N., Seoul, Korea) or co-administration of a single dose of...” NCT05066516 ↗27“The goal of this clinical trial is to find out whether 12 months of treatment with the SGLT2 inhibitor Forxiga® (dapagliflozin 10 mg once daily), compared with placebo, can...” NCT07682350 ↗ “ATB-1011 (Olmetec, Olmesartan medoxomil 40 mg) and ATB-1012 (Forxiga, Dapagliflozin 10 mg) will be co-administered as a single oral dose under fasting conditions (minimum 10...” NCT07590466 ↗ “Dapagliflozin tablet 10 mg relative to Forxiga® film-coated tablets 10 mg, of AstraZeneca pharmaceuticals LP, Mount Vernon, Indiana, USA in healthy Thai volunteers under...” NCT06233045 ↗ “Forxiga® 10 mg Film-Coated Tablet, manufactured by AstraZeneca Pharmaceuticals LP, USA for AstraZeneca Pharmaceuticals Co. Ltd., China imported by PT AstraZeneca Indonesia, Indonesia” NCT06615674 ↗ “The goal of this single arm, prospective study is to test the therapeutic response of oral dapagliflozin (Forxiga) 10 mg/day for 24 weeks in non-diabetic MAFLD patients.” NCT05782972 ↗ “Patients with heart failure with preserved ejection fraction and type 2 diabetes mellitus treated with Dapagliflozin (Forxiga) 10 mg, one capsule per day orally.” NCT04739215 ↗ “FORXIGA(Dapagliflozin Tablets), manufacturer/marketer: AstraZeneca, salt composition: Dapagliflozin (10mg), one tablet once and once a day.” NCT05848102 ↗ “The treatment of Dapagliflozin (Forxiga®) will be initiated and maintained at 10mg every morning until the completion of the study.” NCT04004793 ↗ “patients receiving dapagliflozin (Forxiga; MP-002596) at a dose of 10 mg / day per os in addition to the current therapy” NCT04778787 ↗ “Patients will receive Dapagliflozin 10 mg once daily orally for 12 weeks (Forxiga® AstraZeneca company)” NCT06576375 ↗ “Drug: Dapagliflozin (DAPA) Dose: 10 mg once daily Route: Oral Other Name(s): Forxiga” NCT07076615 ↗ “The product in study is dapagliflozin (FORXIGA™), 10 mg film-coated tablets” NCT02616666 ↗ “dapagliflozin (FORXIGA) might improve lipoprotein metabolism” NCT02577159 ↗ “oral dapagliflozin (Forxiga®) treatment versus placebo” NCT05179356 ↗ “SGLT2is- Dapagliflozin (Forxiga): 10 mg/d, oral drug” NCT05710367 ↗ “Dapagliflozin propanediol (FORXIGA™/FARXIGA™1)” NCT05764057 ↗ “Dapagliflozin (Forxiga), 10 mg tablet daily.” NCT07392151 ↗ “Dapagliflozin 10 MG [Forxiga]” NCT04080518 ↗ “Dapagliflozin (Forxiga) 10mg” NCT04084184 ↗ “Dapagliflozin (Forxiga®)” NCT06072326 ↗ “Dapagliflozin (Forxiga®)” NCT03423355 ↗ “Dapagliflozin (Forxiga®)” NCT06054035 ↗ “Dapagliflozin (Forxiga)” NCT06888505 ↗ “Dapagliflozin (Forxiga)” NCT06690723 ↗ “Dapagliflozin (Forxiga)” NCT07254572 ↗ “Dapagliflozin (Forxiga)” NCT06612086 ↗ “dapagliflozin:Forxiga®️” NCT06344247 ↗ |
| Known as | MP-002596 | “patients receiving dapagliflozin (Forxiga; MP-002596) at a dose of 10 mg / day per os in addition to the current therapy” NCT04778787 ↗ |
| Known as | SGLT2 inhibitor | ClinicalTrials.gov intervention name — accepted as the source's own label NCT04505774 ↗ |
| Known as | THP-00101 | “THP-00101 (Dapagliflozin) 10mg” NCT06063109 ↗ |
| Action | Inhibit | “Dapagliflozin, a novel inhibitor of renal sodium-glucose cotransporter 2” PMID 19114612 ↗ Dec 2008 |
| Modality | Small molecule | “SGLT2 inhibitor dapagliflozin” PMID 42467086 ↗ Jul 2026 |
| Route | Oral | “Tablets, Oral” NCT00263276 ↗ |
| Target | SLC5A2 | “a selective inhibitor of sodium-glucose cotransporter 2” PMID 30415602 ↗ Nov 2018 |