drugset / Trial / NCT06065280
Sodium-glucose Transport 2 Inhibitors (SGLT2i) in HFrEF Patients
RandomizedParallel-groupDouble-blindTreatment
Summary
The aim of this study is to assess the efficacy, safety and cardiovascular outcomes of Sodium-glucose transport protein 2 inhibitors (SGLT2i) therapy in patients with heart failure reduced ejection fraction ( HFrEF) with and without diabetes mellitus and is to evaluate short-term effect of these drugs using the cardiac biomarkers Neopterin.
Timeline
- Start
- 2022-11-01
- Primary completion
- 2024-12-01
- Completion
- 2024-12-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dapagliflozin | Small molecule | 10 mg | — |
| Subject | Empagliflozin | Small molecule | 10 mg | — |