drugset / Trial / NCT06065280

Sodium-glucose Transport 2 Inhibitors (SGLT2i) in HFrEF Patients

NCT06065280

Completed 80 enrolled Damanhour University
RandomizedParallel-groupDouble-blindTreatment

Summary

The aim of this study is to assess the efficacy, safety and cardiovascular outcomes of Sodium-glucose transport protein 2 inhibitors (SGLT2i) therapy in patients with heart failure reduced ejection fraction ( HFrEF) with and without diabetes mellitus and is to evaluate short-term effect of these drugs using the cardiac biomarkers Neopterin.

Timeline

Start
2022-11-01
Primary completion
2024-12-01
Completion
2024-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Dapagliflozin Small molecule 10 mg
Subject Empagliflozin Small molecule 10 mg

Indications