drugset / Trial / NCT06405178

Adjuvant Therapy With Letrozole in Induction of Ovulation With Polycystic Ovarian Syndrome

NCT06405178

Phase 3 Completed 200 enrolled Beni-Suef University
RandomizedParallel-groupSingle-blindTreatment

Summary

The aim of the study is to assess the efficacy of adjuvant therapy dapagliflozin, metformin as monotherapy and combination of both in comparison to control group in induction of ovulation with letrozole in women PCOS, focusing specifically on rates of ovulation and pregnancy.

Timeline

Start
2026-03-30
Primary completion
2026-03-30
Completion
2026-04-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Dapagliflozin Small molecule 10 mg
Subject Dapagliflozin/Metformin Unknown 10 mg
Subject Dapagliflozin/Metformin Unknown 1000 mg
Subject Metformin Small molecule 1000 mg
Background Letrozole Other / unclassified 2.5 mg