drugset / Trial / NCT05938712

The Efficacy, Mechanism & Safety of Sodium Glucose Co-Transporter-2 Inhibitor & Glucagon-Like Peptide 1 Receptor Agonist Combination Therapy in Kidney Transplant Recipients

NCT05938712

Phase 2 Recruiting 20 enrolled University Health Network, Toronto
RandomizedSequentialOpen-labelTreatment

Summary

The study aims to determine the short-term efficacy, mechanisms and safety of 12 weeks of dapagliflozin and semaglutide combination therapy in 20 KTR, with and without T2D.

Timeline

Start
2023-10-24
Primary completion
2027-10-01
Completion
2028-03-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Dapagliflozin Small molecule 10 mg
Subject Semaglutide Peptide 1 mg