Effect of Dapagliflozin on Microvascular Function in Women With Symptoms of Coronary Artery Disease

Summary

The goal of this clinical trial is to test the effects of a drug (in the drug class called sodium-glucose cotransporter 2 inhibitors) in women who have symptoms of ischemic heart disease. The main questions the study aims to answer are: Does blood flow in the heart improve with study drug? Participants will be randomly assigned to a 12-week course of the study drug, dapagliflozin 10mg, or placebo. Blood flow in the heart will be assessed using stress cardiac magnetic resonance imaging at baseline and 12 weeks. The researchers will compare the results from the two groups.

Timeline

Start

2023-06-06

Primary completion

2025-08-05

Completion

2026-03-31

Drugs

Indications