drugset / Trial / NCT00546741

Drug Interaction With Metformin

NCT00546741

Phase 1 Completed 18 enrolled AstraZeneca Bristol-Myers Squibb · collab
RandomizedCrossoverOpen-label

Summary

The purpose of the study is to determine the effect of metformin on dapagliflozin exposure and the effect of dapagliflozin on metformin exposure in healthy volunteers. Additionally, the safety and tolerability of dapagliflozin will be assessed in the presence and absence of metformin in healthy volunteers

Timeline

Start
2007-11
Primary completion
2008-02
Completion
2008-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Dapagliflozin Small molecule 20 mg Oral
Comparator Metformin Small molecule 1000 mg Oral

Indications

No indication recorded.