isoleucine
Trials 5 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT04238416 | Nov 2019 → Dec 2021 | hepatic encephalopathy, liver disorder | Post Graduate Institute of Medical Education and Research, Chandigarh | Completed | No outcome recorded |
| Phase 22 trials | ||||||
| Phase 2 | NCT07670195 | Jul 2026 → Jun 2027 expected | traumatic brain injury, traumatic encephalopathy | Akiva Cohen | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT06829498 | Apr 2025 → Aug 2026 overdue | brain injury, traumatic encephalopathy | Akiva Cohen | Active not recruiting | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT06121479 | Nov 2023 → Sep 2025 overdue | — | Mahidol University | Enrolling by invitation | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT03644836 | Jan 2015 → Jan 2018 | chronic obstructive pulmonary disease | Poitiers University Hospital | Completed | No outcome recorded |
Evidence & citations 7 cited values
Every value below carries the sentence it was read from. 7 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | isoleucine | “In preclinical, analysis of ipsilateral hippocampi isolated from mice after traumatic brain injury (TBI) demonstrated that only the concentrations of the three branched chain...” NCT06829498 ↗4“In preclinical, analysis of ipsilateral hippocampi isolated from mice after traumatic brain injury (TBI) demonstrated that only the concentrations of the three branched chain...” NCT07670195 ↗ “The use of branched-chain amino acids (AARs) such as valine, leucine, isoleucine in this indication can be fully justified because they stimulate protein synthesis and promote...” NCT03644836 ↗ “Each sachet contains 6.84 grams of BCAA (valine 1.82 grams, leucine 3.29 grams, isoleucine 1.72 grams), total protein 17.08 grams, carbohydrates 25.48 grams, fat 5.66 grams,...” NCT06121479 ↗ “Branched-Chain Amino Acids (BCAA; Isoleucine, leucine and valine) have attracted particular interest” PMID 30568347 ↗ Jun 2018 |
| Known as | FEMA NO. 4675 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1233584 ↗ |
| Known as | Isoleucina | ChEMBL registry synonym — accepted as the source's own label CHEMBL1233584 ↗ |
| Known as | L-isoleucine | ChEMBL registry synonym — accepted as the source's own label CHEMBL1233584 ↗ |
| Known as | NSC-46708 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1233584 ↗ |
| Modality | Other / unclassified | “The use of branched-chain amino acids (AARs) such as valine, leucine, isoleucine in this indication can be fully justified because they stimulate protein synthesis and promote...” NCT03644836 ↗ |
| Route | Intravenous | “Intravenous branched chain amino acids will be given for 3 days to patients in experimental arm” NCT04238416 ↗ |