Drugs / Maprotiline
Maprotiline
also known as
BA-34,276 · BA-34,276 [AS HYDROCHLORIDE] · BA-34,276 FREE BASE · BA-34276 HYDROCHLORIDE · Ludiomil · Maprotilina · Maprotiline hcl · MAPROTILINE HYDROCHLORIDE · +1 more
Small molecule targets SLC6A2 via inhibition
Regulatory milestones approvals, filings & regulatory actions · 2 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Label expansion | US (FDA) | LUDIOMIL | — | 1981-05-29 | fda.gov ↗ |
| Approved | US (FDA) | LUDIOMIL | — | 1980-12-01 | fda.gov ↗ |
Trials 2
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT04200066 | Jun 2022 → Oct 2023 | brain neoplasm, glioblastoma | University of Rochester | Withdrawn | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT02374567 | Jan 2015 → Jun 2017 | anxiety disorder, dementia, depressive disorder, schizophrenia +1 | Hannover Medical School | Terminated | No outcome recorded |
Evidence & citations 14 cited values
Every value below carries the sentence it was read from. 3 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Maprotiline | ClinicalTrials.gov intervention name — accepted as the source's own label NCT04200066 ↗ |
| Known as | BA-34,276 | ChEMBL registry synonym — accepted as the source's own label CHEMBL21731 ↗ |
| Known as | BA-34,276 [AS HYDROCHLORIDE] | ChEMBL registry synonym — accepted as the source's own label CHEMBL21731 ↗ |
| Known as | BA-34,276 FREE BASE | ChEMBL registry synonym — accepted as the source's own label CHEMBL21731 ↗ |
| Known as | BA-34276 HYDROCHLORIDE | ChEMBL registry synonym — accepted as the source's own label CHEMBL21731 ↗ |
| Known as | Ludiomil | ChEMBL registry synonym — accepted as the source's own label CHEMBL21731 ↗ |
| Known as | Maprotilina | ChEMBL registry synonym — accepted as the source's own label CHEMBL21731 ↗ |
| Known as | Maprotiline hcl | ChEMBL registry synonym — accepted as the source's own label CHEMBL21731 ↗ |
| Known as | MAPROTILINE HYDROCHLORIDE | ChEMBL registry synonym — accepted as the source's own label CHEMBL21731 ↗ |
| Known as | NSC-757085 | ChEMBL registry synonym — accepted as the source's own label CHEMBL21731 ↗ |
| Action | Inhibit | “Norepinephrine transporter inhibitor” CHEMBL21731 ↗ |
| Modality | Small molecule | — CHEMBL21731 ↗ |
| Route | Oral | “All drugs are administered orally.” NCT04200066 ↗ |
| Target | SLC6A2 | “Norepinephrine transporter inhibitor” CHEMBL21731 ↗ |