drugset / Trial / NCT04200066
A Study of Maprotiline in Combination With Tamoxifen and Temozolomide for Recurrent Glioblastoma
NaSingle-groupOpen-labelTreatment
Summary
The main purpose of this study is to find out the highest possible dose of maprotiline that can be given safely in combination with temozolomide and tamoxifen.
Timeline
- Start
- 2022-06-01
- Primary completion
- 2023-10-01
- Completion
- 2024-02-01
Outcome
Outcome not reported
Stopped: “One of the drugs for the study is not commercially available.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Maprotiline | Small molecule | — | Oral |
| Subject | Tamoxifen | Small molecule | — | Oral |
| Subject | Temozolomide | Small molecule | — | Oral |