Drugs / CoronaVac
last change Jun 2026 re-read 2 minutes ago

CoronaVac

Vaccine

Developed for
COVID-19 · Orthocoronavirinae infectious disease · liver disorder
Investigated by
Sinovac Research and Development Co., Ltd. · China National Biotec Group Company Limited · Sinovac Life Sciences Co., Ltd. · Beijing Institute of Biological Products Co Ltd. · Butantan Institute · Zhejiang Provincial Center for Disease Control and Prevention
+27 more · Sinovac Biotech Co., Ltd · Cigli Regional Training Hospital · D'Or Institute for Research and Education · Hubei Provincial Center for Disease Control and Prevention · Izmir Bakircay University · Jiangsu Province Centers for Disease Control and Prevention · Ministry of Health, Chile · Muğla Sıtkı Koçman University · Pontificia Universidad Catolica de Chile · The University of Hong Kong · Wuhan Institute of Biological Products Co., Ltd · Bill and Melinda Gates Foundation · Centers for Disease Control and Prevention, China · Centro de Pesquisas René Rachou · Coalition for Epidemic Preparedness Innovations · Federal University of Espirito Santo · Health Institutes of Turkey · Hospital do Rim e Hipertensão · Institut Pasteur de Tunis · Instituto Fernandes Figueira · Rinda Ubuzima, Rwanda · Secretaria de Estado da Saúde do Espírito Santo - SESA · Universidad del Desarrollo · University of Chile · University of Kinshasa · University of Sao Paulo General Hospital · Victoria Biomedical Research Institute

Regulatory milestones approvals, filings & regulatory actions · 2 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Withdrawn EU (EMA) COVID-19 Vaccine (inactivated, adjuvanted) Valneva 2023-10-12 europa.eu
Approved EU (EMA) COVID-19 Vaccine (inactivated, adjuvanted) Valneva 2022-06-24 europa.eu

Trials 47 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/23 trials
Phase 1/2 NCT04551547 Oct 2020 → Apr 2021 COVID-19 Sinovac Research and Development Co., Ltd. Completed No outcome recorded
Phase 1/2 NCT04383574 May 2020 → Dec 2021 COVID-19 Sinovac Life Sciences Co., Ltd. Completed No outcome recorded
Phase 1/2 NCT04352608 Apr → Jul 2020 COVID-19 Sinovac Research and Development Co., Ltd. Completed No outcome recorded
Phase 27 trials
Phase 2 NCT05150496 Dec 2022 → Jan 2023 COVID-19 Sinovac Research and Development Co., Ltd. Suspended No outcome recorded
Phase 2 NCT07408297 May 2022 → Jun 2024 COVID-19 Victoria Biomedical Research Institute Completed No outcome recorded
Phase 2 NCT05254236 Feb → Mar 2022 COVID-19 Sinovac Research and Development Co., Ltd. Withdrawn No outcome recorded
Phase 2 NCT05087368 Dec 2021 → Apr 2022 COVID-19 D'Or Institute for Research and Education Unknown No outcome recorded
Phase 2 NCT04992182 Jul → Aug 2021 COVID-19 Universidad del Desarrollo Unknown No outcome recorded
Phase 2 NCT04800133 May 2021 → Mar 2025 COVID-19 The University of Hong Kong Unknown No outcome recorded
Phase 2 NCT04884685 May → Aug 2021 COVID-19 Sinovac Life Sciences Co., Ltd. Completed No outcome recorded
Phase 38 trials
Phase 3 NCT05156632 Feb 2023 COVID-19 Sinovac Research and Development Co., Ltd. Withdrawn No outcome recorded
Phase 3 NCT05225285 Jan → Jun 2022 COVID-19 Federal University of Espirito Santo Unknown No outcome recorded
Phase 3 NCT05137418 Nov 2021 → Jan 2023 COVID-19 Sinovac Research and Development Co., Ltd. Completed No outcome recorded
Phase 3 NCT05668065 Nov 2021 → Jan 2022 COVID-19 Institut Pasteur de Tunis Completed No outcome recorded
Phase 3 NCT04992260 Sep 2021 → May 2023 COVID-19 Sinovac Research and Development Co., Ltd. Completed No outcome recorded
Phase 3 NCT04651790 Nov 2020 → Aug 2022 COVID-19 Pontificia Universidad Catolica de Chile Completed No outcome recorded
Phase 3 NCT04582344 Sep 2020 → Jun 2022 COVID-19 Health Institutes of Turkey Completed No outcome recorded
Phase 3 NCT04456595 Jul → Dec 2020 COVID-19 Butantan Institute Completed No outcome recorded
Phase 427 trials
Phase 4 NCT05165732 Dec 2022 → Mar 2023 COVID-19 Sinovac Research and Development Co., Ltd. Suspended No outcome recorded
Phase 4 NCT05303584 Apr → Jun 2022 COVID-19 Jiangsu Province Centers for Disease Control and Prevention Completed No outcome recorded
Phase 4 NCT05329038 Apr → Jun 2022 COVID-19 Sinovac Life Sciences Co., Ltd. Unknown No outcome recorded
Phase 4 NCT05198336 Jan 2022 COVID-19 Sinovac Research and Development Co., Ltd. Completed No outcome recorded
Phase 4 NCT05148949 Dec 2021 → Dec 2022 COVID-19, pulmonary tuberculosis Jiangsu Province Centers for Disease Control and Prevention Unknown No outcome recorded
Phase 4 NCT05079217 Dec 2021 COVID-19 Sinovac Biotech Co., Ltd Unknown No outcome recorded
Phase 4 NCT05398926 Dec 2021 → Jun 2022 COVID-19 Sinovac Life Sciences Co., Ltd. Completed No outcome recorded
Phase 4 NCT05105295 Dec 2021 → Jun 2022 COVID-19, HIV infectious disease China National Biotec Group Company Limited Unknown No outcome recorded
Phase 4 NCT05104216 Dec 2021 → Jun 2022 COVID-19, chronic bronchitis China National Biotec Group Company Limited Unknown No outcome recorded
Phase 4 NCT05057169 Nov 2021 → Dec 2024 The University of Hong Kong Completed No outcome recorded
Phase not applicable2 trials
NCT04751721 Feb → Mar 2021 Izmir Bakircay University Unknown No outcome recorded
NCT04751695 Feb → Mar 2021 Izmir Bakircay University Unknown No outcome recorded
Also used as a comparator or background therapy in 32 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 03 trials
Phase 0 NCT05918939 Comparator Sep 2022 → Aug 2023 COVID-19 Dr. Soetomo General Hospital Unknown No outcome recorded
Phase 0 NCT05583357 Comparator Aug → Sep 2022 COVID-19 Livzon Pharmaceutical Group Inc. Unknown No outcome recorded
Phase 0 NCT05928455 Comparator May → Oct 2022 COVID-19, vaccinia Guangzhou Patronus Biotech Co., Ltd. Unknown No outcome recorded
Phase 14 trials
Phase 1 NCT06113744 Comparator Mar → Jun 2023 COVID-19 CNBG-Virogin Biotech (Shanghai) Ltd. Unknown No outcome recorded
Phase 1 NCT05897190 Comparator May → Jun 2022 Orthocoronavirinae infectious disease Argorna Pharmaceuticals Co., LTD Completed No outcome recorded
Phase 1 NCT05228613 Comparator Feb → Aug 2022 COVID-19 PT Bio Farma Completed No outcome recorded
Phase 1 NCT05067894 Comparator Dec 2021 → Apr 2022 COVID-19 PT Bio Farma Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT05043259 Comparator Aug → Nov 2021 COVID-19 Jiangsu Province Centers for Disease Control and Prevention Completed No outcome recorded
Phase 27 trials
Phase 2 NCT06113731 Comparator Jul → Oct 2023 COVID-19 CNBG-Virogin Biotech (Shanghai) Ltd. Unknown No outcome recorded
Phase 2 NCT05465902 Comparator Jul 2023 → Nov 2024 COVID-19 WestVac Biopharma Co., Ltd. Withdrawn No outcome recorded
Phase 2 NCT05593042 Comparator Nov 2022 → Oct 2023 COVID-19 Pontificia Universidad Catolica de Chile Completed No outcome recorded
Phase 2 NCT05463354 Comparator Jul → Aug 2022 COVID-19 WestVac Biopharma Co., Ltd. Completed No outcome recorded
Phase 2 NCT05323435 Comparator May → Jul 2022 COVID-19 Jiangsu Rec-Biotechnology Co., Ltd. Completed No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT05463419 Comparator Oct 2022 → Dec 2023 Yisheng Biopharma (Singapore) Pte. Ltd. Completed No outcome recorded
Phase 310 trials
Phase 3 NCT05433272 Comparator Aug → Sep 2023 COVID-19 Sinovac Biotech (Colombia) S.A.S. Unknown No outcome recorded
Phase 3 NCT05428592 Comparator Apr → Oct 2023 Orthocoronavirinae infectious disease AIM Vaccine Co., Ltd. Unknown No outcome recorded
Phase 3 NCT05683561 Comparator Jan → Aug 2023 COVID-19 Sinocelltech Ltd. Unknown No outcome recorded
Phase 3 NCT05508477 Comparator Jun 2022 → Mar 2023 COVID-19 Dr. Soetomo General Hospital Unknown No outcome recorded
Phase 3 NCT05188677 Comparator Jun 2022 → Jun 2023 COVID-19 Clover Biopharmaceuticals AUS Pty Completed No outcome recorded
Phase 45 trials
Phase 4 NCT04993365 Comparator Nov 2021 → Jul 2022 COVID-19 Sinovac Research and Development Co., Ltd. Completed No outcome recorded
Phase 4 NCT04952727 Comparator Aug → Nov 2021 COVID-19 Jiangsu Province Centers for Disease Control and Prevention Completed No outcome recorded
Phase 4 NCT04892459 Comparator May → Jul 2021 COVID-19 Jiangsu Province Centers for Disease Control and Prevention Completed No outcome recorded
Phase 4 NCT04775069 Comparator May 2021 → Sep 2023 liver disorder Humanity & Health Medical Group Limited Completed No outcome recorded
Phase 4 NCT04789356 Comparator Mar → Jul 2021 COVID-19 Fundação de Medicina Tropical Dr. Heitor Vieira Dourado Unknown No outcome recorded
Phase not applicable1 trial
NCT06381843 Comparator Aug 2022 → Mar 2023 COVID-19 WestVac Biopharma Co., Ltd. Completed No outcome recorded

Evidence & citations 14 cited values

Every value below carries the sentence it was read from. 82 sources stand behind the page.

FieldValueCited text
Known as CoronaVac “A Randomized, Open, Control Phase ⅠV Clinical Trial, to Evaluate One Booster Immunization of Inactivated COVID-19 Vaccine (CoronaVac) or Original Vaccine in Adults Aged 18-45...” NCT05165732
44

“One of the vaccines developed, the China-based CoronaVac vaccine (inactivated + aluminum adjuvant vaccine) is a vaccine developed with the inactive method, which is the...” NCT04751721

“Here we aimed to assess the safety, tolerability, and immunogenicity of a candidate COVID-19 vaccine, CoronaVac, containing inactivated SARS-CoV-2, in children and adolescents...” PMID 34197764 Jun 2021

“This study will assess safety and immunogenicity of the inactivated vaccine adsorbed against COVID-19 (CoronaVac) in a population of healthy individuals older than 18 years of age.” NCT04756830

“a third booster dose of SARS-CoV-2 inactivated vaccine (CoronaVac), inactivated quadrivalent influenza vaccine (IIV4), and 23-valent pneumococcal polysaccharide vaccine (PPV23)” PMID 39229259 Aug 2024

“We did a randomised, double-blind, placebo-controlled, phase 1/2 clinical trial of CoronaVac in healthy adults aged 60 years and older in Renqiu (Hebei, China).” PMID 33548194 Feb 2021

CoronaVac vaccine (inactivated + aluminum adjuvant vaccine) is a vaccine developed with the inactive method, which is the classic vaccine production method.” NCT04751695

“Previous phase I to III clinical trials have shown that the inactivated SARS-CoV-2 vaccine namely CoronaVac has good efficacy, safety, and immunogenicity.” PMID 36441137 Nov 2022

“This study is an open phase 4 clinical trial of an inactivated COVID-19 vaccine (CoronaVac) manufactured by Sinovac Research and Development Co., Ltd.” NCT05198336

“The inactivated vaccine CoronaVac has been shown to be safe and immunogenic in a phase 1/2 clinical trial in a pediatric cohort in China.” PMID 36383021 Nov 2022

“Kidney transplant recipients aged 30-69 y with >30 d of transplantation received two 3 µg intramuscular doses of CoronaVac 28 d apart” PMID 34882589 Apr 2022

“First dose of Coronavac. Each innoculation dose is 0.5 ml containing 600 SU in-house unit (equals to 3μg) of SARS-CoV-2 antigen.” NCT05668065

CoronaVac is an inactivated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine approved for emergency use” PMID 36226829 Oct 2022

“investigated CoronaVac (Sinovac Life Sciences, Beijing, China), an inactivated vaccine candidate against COVID-19” PMID 33217362 Nov 2020

CoronaVac, an inactivated SARS-CoV-2 vaccine, was one of the first deployed during the COVID-19 pandemic.” PMID 42329996 Jun 2026

“Sinopharm's BBIBP-CorV and Sinovac's CoronaVac are inactivated whole-virus COVID-19 vaccines.” NCT07408297

“or a homologous intramuscular vaccination with CoronaVac (0·5 mL).” PMID 35605625 May 2022

“third dose of inactivated COVID-19 vaccine(CoronaVac)” NCT05499351

“an inactivated vaccine (CoronaVac) previously” PMID 37360864 Jun 2023

“inactivated COVID-19 vaccine (CoronaVac®)” PMID 39313857 Sep 2024

“inactivated COVID-19 vaccine (CoronaVac)” NCT05148949

“One standard IM CoronaVac dose (0.5 mL)” NCT04992182

NCT04800133

NCT04942405

NCT04979949

NCT05077176

NCT05508477

NCT05683561

NCT05230940

NCT05928455

NCT04754698

NCT04582344

NCT05897190

NCT05583357

NCT05225285

NCT05428592

NCT05668065

NCT05918939

NCT05057169

NCT05087368

NCT05593042

NCT05188677

NCT04775069

NCT05303584

NCT04801667

Known as Adsorbed COVID-19 (Inactivated) Vaccine ClinicalTrials.gov intervention name — accepted as the source's own label NCT04747821
1

NCT04456595

Known as CoronaVac vaccine “One of the vaccines developed, the China-based CoronaVac vaccine (inactivated + aluminum adjuvant vaccine) is a vaccine developed with the inactive method, which is the...” NCT04751721
Known as COVID-19 Vaccine (Vero Cell), Inactivated ClinicalTrials.gov intervention name — accepted as the source's own label NCT05374954
13

NCT05463354

NCT05254236

NCT05323435

NCT05150496

NCT05165966

NCT05382871

NCT05398926

NCT04863638

NCT05433272

NCT06381843

NCT06113731

NCT05465902

NCT06113744

Known as COVID-19 Vaccine (Vero cell), Inactivated (CZ strain) ClinicalTrials.gov intervention name — accepted as the source's own label NCT05381350
Known as COVID-19 Vaccine,Inactivated ClinicalTrials.gov intervention name — accepted as the source's own label NCT05156632
1

NCT05137418

Known as Covilo “In this prospective cohort study, we analyzed the safety and immunogenicity of a two-dose schedule of the inactivated COVID-19 vaccine (Covilo) in people living with HIV (PLWH).” PMID 40838719 Aug 2025
1

“Study-1 involved subjects were randomized (1:1:1) to receive 20 μg ReCOV, 40 μg ReCOV, or an inactivated vaccine (COVILO®) in the United Arab Emirates.” PMID 38529685 Apr 2024

Known as Inactivated Covid-19 vaccine ClinicalTrials.gov intervention name — accepted as the source's own label NCT05463419
9

NCT04953325

NCT05104216

NCT05075083

NCT05075057

NCT05105295

NCT05075044

NCT05198336

NCT05329038

NCT05075070

Known as Inactive SARS-CoV-2 vaccine (Vero cell) ClinicalTrials.gov intervention name — accepted as the source's own label NCT04892459
Known as SARS-CoV-2 Inactivated Vaccine SARS-CoV-2 Inactivated Vaccine 1200SU inactivated virus in 0.5 mL of aluminium hydroxide solution per injection” NCT05079217
6

SARS-CoV-2 Inactivated Vaccine 600SU inactivated virus in 0·5 mL of aluminium hydroxide solution per injection” NCT04992208

SARS-CoV-2 Inactivated Vaccine 600SU inactivated virus in 0·5 mL of aluminiumhydroxide solution per injection” NCT04911790

NCT04884685

NCT05067894

NCT04962308

NCT05228613

Known as Sinovac “The subjects will be vaccinated with inactivated SARS Cov-2 (Sinovac).” NCT04775069
1

“two-doses CoronaVac (Sinovac) vaccine” NCT05230940

Known as Sinovac CoronaVac “two doses of an inactivated SARS-CoV-2 vaccine-Sinovac CoronaVac.” PMID 35605625 May 2022
Modality Vaccine “candidate COVID-19 vaccine, CoronaVac, containing inactivated SARS-CoV-2” PMID 33548194 Feb 2021
Route Intramuscular “Vaccine or placebo was given by intramuscular injection in two doses (days 0 and 28).” PMID 33548194 Feb 2021